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Zinc in PDB 6r11: Cereblon Isoform 4 From Magnetospirillum Gryphiswaldense in Complex with Compound 5BProtein crystallography data
The structure of Cereblon Isoform 4 From Magnetospirillum Gryphiswaldense in Complex with Compound 5B, PDB code: 6r11
was solved by
C.Heim,
M.D.Hartmann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6r11:
The structure of Cereblon Isoform 4 From Magnetospirillum Gryphiswaldense in Complex with Compound 5B also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Cereblon Isoform 4 From Magnetospirillum Gryphiswaldense in Complex with Compound 5B
(pdb code 6r11). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Cereblon Isoform 4 From Magnetospirillum Gryphiswaldense in Complex with Compound 5B, PDB code: 6r11: Jump to Zinc binding site number: 1; 2; 3; Zinc binding site 1 out of 3 in 6r11Go back to Zinc Binding Sites List in 6r11
Zinc binding site 1 out
of 3 in the Cereblon Isoform 4 From Magnetospirillum Gryphiswaldense in Complex with Compound 5B
Mono view Stereo pair view
Zinc binding site 2 out of 3 in 6r11Go back to Zinc Binding Sites List in 6r11
Zinc binding site 2 out
of 3 in the Cereblon Isoform 4 From Magnetospirillum Gryphiswaldense in Complex with Compound 5B
Mono view Stereo pair view
Zinc binding site 3 out of 3 in 6r11Go back to Zinc Binding Sites List in 6r11
Zinc binding site 3 out
of 3 in the Cereblon Isoform 4 From Magnetospirillum Gryphiswaldense in Complex with Compound 5B
Mono view Stereo pair view
Reference:
C.Heim,
D.Pliatsika,
F.Mousavizadeh,
K.Bar,
B.Hernandez Alvarez,
A.Giannis,
M.D.Hartmann.
De-Novo Design of Cereblon (Crbn) Effectors Guided By Natural Hydrolysis Products of Thalidomide Derivatives. J.Med.Chem. V. 62 6615 2019.
Page generated: Wed Dec 16 12:35:16 2020
ISSN: ISSN 0022-2623 PubMed: 31251063 DOI: 10.1021/ACS.JMEDCHEM.9B00454 |
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