Zinc in PDB 6q9v: MSRB3

All present enzymatic activity of MSRB3:
1.8.4.12; 1.8.4.14;

The structure of MSRB3, PDB code: 6q9v was solved by G.Javitt, D.Fass, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	56.44 / 1.85
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	44.025, 65.183, 112.777, 90.00, 90.00, 90.00
R / Rfree (%)	18.2 / 22.6

The binding sites of Zinc atom in the MSRB3 (pdb code 6q9v). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the MSRB3, PDB code: 6q9v:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the MSRB3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of MSRB3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:16.1 occ:1.00 SG A:CYS106 2.3 16.1 1.0 SG A:CYS54 2.3 14.1 1.0 SG A:CYS57 2.4 16.0 1.0 SG A:CYS103 2.4 15.6 1.0 CB A:CYS103 3.2 14.8 1.0 CB A:CYS54 3.2 13.1 1.0 CB A:CYS106 3.4 18.2 1.0 CB A:CYS57 3.4 15.1 1.0 N A:CYS57 3.8 15.6 1.0 N A:CYS106 3.8 17.0 1.0 CA A:CYS106 4.1 19.1 1.0 CA A:CYS57 4.2 16.8 1.0 CB A:ALA108 4.4 14.9 1.0 CB A:VAL56 4.5 14.6 1.0 CA A:CYS103 4.6 14.4 1.0 CA A:CYS54 4.7 12.4 1.0 OG1 A:THR59 4.7 19.8 1.0 CB A:GLN105 4.7 15.5 1.0 C A:CYS106 4.7 15.9 1.0 N A:GLY107 4.8 14.7 1.0 C A:GLN105 4.8 18.6 1.0 C A:VAL56 4.8 14.7 1.0 N A:ALA108 4.8 12.8 1.0 CB A:THR59 4.9 20.1 1.0 C A:CYS57 4.9 21.8 1.0 N A:GLY58 5.0 15.0 1.0

Zinc binding site 2 out of 2 in the MSRB3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of MSRB3 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:18.1 occ:1.00 SG B:CYS106 2.3 18.0 1.0 SG B:CYS54 2.3 14.6 1.0 SG B:CYS103 2.3 18.0 1.0 SG B:CYS57 2.4 17.8 1.0 CB B:CYS103 3.1 16.2 1.0 CB B:CYS54 3.1 13.4 1.0 CB B:CYS106 3.4 19.6 1.0 CB B:CYS57 3.4 14.5 1.0 N B:CYS57 3.8 14.8 1.0 N B:CYS106 3.9 15.7 1.0 CA B:CYS106 4.2 15.1 1.0 CA B:CYS57 4.2 15.9 1.0 CB B:ALA108 4.4 12.2 1.0 CB B:VAL56 4.6 17.0 1.0 CA B:CYS103 4.6 18.6 1.0 CA B:CYS54 4.6 12.5 1.0 C B:CYS106 4.7 15.4 1.0 OG1 B:THR59 4.7 20.3 1.0 N B:ALA108 4.7 15.1 1.0 CB B:GLN105 4.8 17.0 1.0 CB B:THR59 4.8 17.1 1.0 C B:VAL56 4.8 17.6 1.0 C B:CYS57 4.9 18.3 1.0 N B:GLY107 4.9 19.6 1.0 C B:GLN105 4.9 21.1 1.0

G.Javitt, Z.Cao, N.Bulleid, D.Fass. Structure of A Human Endoplasmic Reticulum Methionine Sulfoxide Reductase To Be Published.