Zinc in PDB 6q3m: Structure of CHD4 PHD2 - Tandem Chromodomains
Enzymatic activity of Structure of CHD4 PHD2 - Tandem Chromodomains
All present enzymatic activity of Structure of CHD4 PHD2 - Tandem Chromodomains:
3.6.4.12;
Protein crystallography data
The structure of Structure of CHD4 PHD2 - Tandem Chromodomains, PDB code: 6q3m
was solved by
A.Alt,
E.J.Mancini,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
64.50 /
2.52
|
|
Space group
|
P 1 21 1
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
70.731,
87.681,
129.257,
90.00,
93.57,
90.00
|
|
R / Rfree (%)
|
23 /
26.3
|
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of CHD4 PHD2 - Tandem Chromodomains
(pdb code 6q3m). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the
Structure of CHD4 PHD2 - Tandem Chromodomains, PDB code: 6q3m:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Zinc binding site 1 out
of 8 in 6q3m
Go back to
Zinc Binding Sites List in 6q3m
Zinc binding site 1 out
of 8 in the Structure of CHD4 PHD2 - Tandem Chromodomains
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Structure of CHD4 PHD2 - Tandem Chromodomains within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn701
b:50.4
occ:1.00
|
SG
|
A:CYS467
|
2.2
|
46.6
|
1.0
|
|
SG
|
A:CYS493
|
2.2
|
58.9
|
1.0
|
|
SG
|
A:CYS490
|
2.2
|
39.8
|
1.0
|
|
SG
|
A:CYS464
|
2.4
|
49.2
|
1.0
|
|
H
|
A:CYS490
|
3.1
|
51.2
|
1.0
|
|
HB2
|
A:CYS464
|
3.2
|
60.3
|
1.0
|
|
HB3
|
A:CYS467
|
3.3
|
57.3
|
1.0
|
|
HB2
|
A:CYS493
|
3.3
|
56.4
|
1.0
|
|
CB
|
A:CYS464
|
3.3
|
50.3
|
1.0
|
|
CB
|
A:CYS467
|
3.4
|
47.8
|
1.0
|
|
HB3
|
A:CYS464
|
3.4
|
60.3
|
1.0
|
|
H
|
A:CYS493
|
3.4
|
52.5
|
1.0
|
|
HB3
|
A:CYS490
|
3.4
|
48.5
|
1.0
|
|
CB
|
A:CYS493
|
3.4
|
47.0
|
1.0
|
|
CB
|
A:CYS490
|
3.4
|
40.4
|
1.0
|
|
HG1
|
A:THR466
|
3.6
|
73.5
|
1.0
|
|
H12
|
A:EDO709
|
3.6
|
69.1
|
1.0
|
|
HO1
|
A:EDO709
|
3.7
|
66.6
|
1.0
|
|
HB2
|
A:SER469
|
3.7
|
63.0
|
1.0
|
|
H
|
A:CYS467
|
3.9
|
56.1
|
1.0
|
|
N
|
A:CYS490
|
3.9
|
42.7
|
1.0
|
|
N
|
A:CYS467
|
3.9
|
46.8
|
1.0
|
|
N
|
A:CYS493
|
3.9
|
43.7
|
1.0
|
|
HB2
|
A:ARG492
|
4.0
|
57.3
|
1.0
|
|
HB2
|
A:CYS467
|
4.1
|
57.3
|
1.0
|
|
HB3
|
A:CYS493
|
4.1
|
56.4
|
1.0
|
|
CA
|
A:CYS467
|
4.2
|
48.5
|
1.0
|
|
CA
|
A:CYS490
|
4.2
|
41.1
|
1.0
|
|
H
|
A:THR466
|
4.2
|
72.0
|
1.0
|
|
HB2
|
A:CYS490
|
4.2
|
48.5
|
1.0
|
|
CA
|
A:CYS493
|
4.3
|
42.8
|
1.0
|
|
OG1
|
A:THR466
|
4.3
|
61.2
|
1.0
|
|
HG
|
A:SER469
|
4.3
|
68.9
|
1.0
|
|
H
|
A:SER469
|
4.4
|
64.5
|
1.0
|
|
C
|
A:THR466
|
4.4
|
54.3
|
1.0
|
|
O1
|
A:EDO709
|
4.4
|
55.5
|
1.0
|
|
C1
|
A:EDO709
|
4.4
|
57.6
|
1.0
|
|
CB
|
A:SER469
|
4.6
|
52.5
|
1.0
|
|
HA
|
A:CYS493
|
4.6
|
51.4
|
1.0
|
|
H
|
A:ARG492
|
4.6
|
61.8
|
1.0
|
|
O
|
A:CYS490
|
4.6
|
40.7
|
1.0
|
|
OG
|
A:SER469
|
4.6
|
57.4
|
1.0
|
|
C
|
A:CYS490
|
4.7
|
40.3
|
1.0
|
|
HA
|
A:LEU489
|
4.7
|
67.2
|
1.0
|
|
C
|
A:CYS467
|
4.7
|
46.6
|
1.0
|
|
O
|
A:CYS467
|
4.7
|
50.9
|
1.0
|
|
CA
|
A:CYS464
|
4.7
|
51.3
|
1.0
|
|
O
|
A:THR466
|
4.8
|
57.4
|
1.0
|
|
CB
|
A:ARG492
|
4.9
|
47.8
|
1.0
|
|
H22
|
A:EDO709
|
4.9
|
72.4
|
1.0
|
|
C
|
A:ARG492
|
4.9
|
46.7
|
1.0
|
|
N
|
A:THR466
|
5.0
|
60.0
|
1.0
|
|
HA
|
A:CYS464
|
5.0
|
61.6
|
1.0
|
|
Zinc binding site 2 out
of 8 in 6q3m
Go back to
Zinc Binding Sites List in 6q3m
Zinc binding site 2 out
of 8 in the Structure of CHD4 PHD2 - Tandem Chromodomains
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Structure of CHD4 PHD2 - Tandem Chromodomains within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn702
b:52.3
occ:1.00
|
ND1
|
A:HIS472
|
2.2
|
59.8
|
1.0
|
|
SG
|
A:CYS475
|
2.3
|
56.8
|
1.0
|
|
SG
|
A:CYS455
|
2.3
|
53.7
|
1.0
|
|
SG
|
A:CYS452
|
2.5
|
49.6
|
1.0
|
|
HB3
|
A:CYS452
|
2.8
|
61.4
|
1.0
|
|
HB2
|
A:HIS472
|
2.9
|
55.5
|
1.0
|
|
H
|
A:CYS455
|
3.0
|
62.5
|
1.0
|
|
CB
|
A:CYS452
|
3.1
|
51.2
|
1.0
|
|
HB3
|
A:CYS455
|
3.1
|
67.4
|
1.0
|
|
HB2
|
A:CYS452
|
3.1
|
61.4
|
1.0
|
|
CE1
|
A:HIS472
|
3.2
|
52.0
|
1.0
|
|
HB2
|
A:CYS475
|
3.2
|
57.4
|
1.0
|
|
CG
|
A:HIS472
|
3.2
|
50.7
|
1.0
|
|
CB
|
A:CYS475
|
3.3
|
47.9
|
1.0
|
|
HE1
|
A:HIS472
|
3.3
|
62.4
|
1.0
|
|
CB
|
A:CYS455
|
3.3
|
56.2
|
1.0
|
|
HB
|
A:VAL454
|
3.4
|
58.5
|
1.0
|
|
H
|
A:HIS472
|
3.5
|
51.6
|
1.0
|
|
CB
|
A:HIS472
|
3.5
|
46.2
|
1.0
|
|
HB3
|
A:CYS475
|
3.6
|
57.4
|
1.0
|
|
N
|
A:CYS455
|
3.7
|
52.1
|
1.0
|
|
CA
|
A:CYS455
|
4.1
|
55.4
|
1.0
|
|
HB2
|
A:CYS455
|
4.1
|
67.4
|
1.0
|
|
HE2
|
A:HIS474
|
4.1
|
67.7
|
1.0
|
|
N
|
A:HIS472
|
4.2
|
43.0
|
1.0
|
|
HG12
|
A:VAL454
|
4.2
|
56.5
|
1.0
|
|
H
|
A:VAL454
|
4.2
|
58.0
|
1.0
|
|
HB3
|
A:HIS472
|
4.2
|
55.5
|
1.0
|
|
NE2
|
A:HIS472
|
4.3
|
54.7
|
1.0
|
|
CD2
|
A:HIS472
|
4.3
|
53.2
|
1.0
|
|
CB
|
A:VAL454
|
4.4
|
48.8
|
1.0
|
|
H
|
A:ASP457
|
4.4
|
73.8
|
1.0
|
|
NE2
|
A:HIS474
|
4.5
|
56.4
|
1.0
|
|
CA
|
A:HIS472
|
4.5
|
45.6
|
1.0
|
|
H
|
A:LYS456
|
4.5
|
72.7
|
1.0
|
|
CA
|
A:CYS452
|
4.5
|
51.4
|
1.0
|
|
CA
|
A:CYS475
|
4.7
|
43.4
|
1.0
|
|
C
|
A:VAL454
|
4.7
|
48.9
|
1.0
|
|
HB2
|
A:ASP457
|
4.7
|
80.0
|
1.0
|
|
CG1
|
A:VAL454
|
4.8
|
47.1
|
1.0
|
|
H
|
A:CYS475
|
4.8
|
57.8
|
1.0
|
|
C
|
A:CYS455
|
4.8
|
58.4
|
1.0
|
|
HA
|
A:CYS455
|
4.9
|
66.4
|
1.0
|
|
CA
|
A:VAL454
|
4.9
|
47.9
|
1.0
|
|
N
|
A:VAL454
|
4.9
|
48.4
|
1.0
|
|
N
|
A:LYS456
|
4.9
|
60.5
|
1.0
|
|
HA
|
A:CYS475
|
4.9
|
52.1
|
1.0
|
|
HA
|
A:CYS452
|
5.0
|
61.6
|
1.0
|
|
Zinc binding site 3 out
of 8 in 6q3m
Go back to
Zinc Binding Sites List in 6q3m
Zinc binding site 3 out
of 8 in the Structure of CHD4 PHD2 - Tandem Chromodomains
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Structure of CHD4 PHD2 - Tandem Chromodomains within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn701
b:50.4
occ:1.00
|
SG
|
B:CYS490
|
2.2
|
43.9
|
1.0
|
|
SG
|
B:CYS464
|
2.3
|
47.9
|
1.0
|
|
SG
|
B:CYS493
|
2.3
|
48.6
|
1.0
|
|
SG
|
B:CYS467
|
2.4
|
42.1
|
1.0
|
|
HB2
|
B:CYS464
|
3.1
|
54.8
|
1.0
|
|
HG1
|
B:THR466
|
3.1
|
65.7
|
1.0
|
|
CB
|
B:CYS464
|
3.1
|
45.7
|
1.0
|
|
H
|
B:CYS490
|
3.1
|
52.4
|
1.0
|
|
HB3
|
B:CYS464
|
3.1
|
54.8
|
1.0
|
|
HB3
|
B:CYS467
|
3.2
|
53.3
|
1.0
|
|
HB3
|
B:CYS490
|
3.3
|
52.2
|
1.0
|
|
HB2
|
B:CYS493
|
3.3
|
59.2
|
1.0
|
|
CB
|
B:CYS467
|
3.3
|
44.4
|
1.0
|
|
CB
|
B:CYS490
|
3.4
|
43.5
|
1.0
|
|
CB
|
B:CYS493
|
3.5
|
49.3
|
1.0
|
|
H
|
B:CYS493
|
3.5
|
60.0
|
1.0
|
|
H
|
B:CYS467
|
3.5
|
59.4
|
1.0
|
|
HB2
|
B:SER469
|
3.7
|
49.7
|
1.0
|
|
OG1
|
B:THR466
|
3.7
|
54.8
|
1.0
|
|
N
|
B:CYS467
|
3.8
|
49.5
|
1.0
|
|
N
|
B:CYS490
|
3.9
|
43.6
|
1.0
|
|
HB2
|
B:ARG492
|
3.9
|
56.9
|
1.0
|
|
N
|
B:CYS493
|
4.0
|
50.0
|
1.0
|
|
CA
|
B:CYS467
|
4.1
|
46.2
|
1.0
|
|
HG
|
B:SER469
|
4.1
|
58.9
|
1.0
|
|
H
|
B:THR466
|
4.1
|
62.0
|
1.0
|
|
HB2
|
B:CYS490
|
4.1
|
52.2
|
1.0
|
|
HB2
|
B:CYS467
|
4.2
|
53.3
|
1.0
|
|
CA
|
B:CYS490
|
4.2
|
43.2
|
1.0
|
|
HB3
|
B:CYS493
|
4.2
|
59.2
|
1.0
|
|
H
|
B:SER469
|
4.3
|
58.1
|
1.0
|
|
CA
|
B:CYS493
|
4.4
|
47.9
|
1.0
|
|
C
|
B:THR466
|
4.4
|
47.8
|
1.0
|
|
OG
|
B:SER469
|
4.5
|
49.0
|
1.0
|
|
CB
|
B:SER469
|
4.5
|
41.4
|
1.0
|
|
CA
|
B:CYS464
|
4.6
|
47.2
|
1.0
|
|
C
|
B:CYS467
|
4.6
|
42.3
|
1.0
|
|
O
|
B:CYS490
|
4.6
|
43.1
|
1.0
|
|
C
|
B:CYS490
|
4.7
|
42.9
|
1.0
|
|
HA
|
B:CYS493
|
4.7
|
57.5
|
1.0
|
|
O
|
B:CYS467
|
4.7
|
43.8
|
1.0
|
|
H
|
B:ARG492
|
4.7
|
57.4
|
1.0
|
|
HA
|
B:LEU489
|
4.8
|
57.6
|
1.0
|
|
HA
|
B:CYS464
|
4.8
|
56.6
|
1.0
|
|
CB
|
B:ARG492
|
4.9
|
47.4
|
1.0
|
|
N
|
B:THR466
|
4.9
|
51.6
|
1.0
|
|
CB
|
B:THR466
|
4.9
|
50.0
|
1.0
|
|
HA
|
B:CYS467
|
4.9
|
55.5
|
1.0
|
|
CA
|
B:THR466
|
4.9
|
50.0
|
1.0
|
|
C
|
B:ARG492
|
5.0
|
49.7
|
1.0
|
|
Zinc binding site 4 out
of 8 in 6q3m
Go back to
Zinc Binding Sites List in 6q3m
Zinc binding site 4 out
of 8 in the Structure of CHD4 PHD2 - Tandem Chromodomains
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Structure of CHD4 PHD2 - Tandem Chromodomains within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn702
b:50.4
occ:1.00
|
ND1
|
B:HIS472
|
2.2
|
41.5
|
1.0
|
|
SG
|
B:CYS455
|
2.3
|
50.9
|
1.0
|
|
SG
|
B:CYS475
|
2.3
|
50.1
|
1.0
|
|
SG
|
B:CYS452
|
2.4
|
38.5
|
1.0
|
|
HB3
|
B:CYS452
|
2.7
|
51.9
|
1.0
|
|
HB2
|
B:HIS472
|
2.8
|
49.9
|
1.0
|
|
CB
|
B:CYS452
|
2.9
|
43.2
|
1.0
|
|
HB2
|
B:CYS452
|
2.9
|
51.9
|
1.0
|
|
H
|
B:CYS455
|
3.0
|
44.4
|
1.0
|
|
CE1
|
B:HIS472
|
3.2
|
40.4
|
1.0
|
|
HB3
|
B:CYS455
|
3.2
|
46.8
|
1.0
|
|
CG
|
B:HIS472
|
3.2
|
41.2
|
1.0
|
|
HB2
|
B:CYS475
|
3.2
|
55.5
|
1.0
|
|
HE1
|
B:HIS472
|
3.3
|
48.5
|
1.0
|
|
CB
|
B:CYS455
|
3.3
|
39.0
|
1.0
|
|
CB
|
B:CYS475
|
3.4
|
46.2
|
1.0
|
|
H
|
B:HIS472
|
3.5
|
47.9
|
1.0
|
|
CB
|
B:HIS472
|
3.5
|
41.5
|
1.0
|
|
HB3
|
B:CYS475
|
3.6
|
55.5
|
1.0
|
|
N
|
B:CYS455
|
3.7
|
37.0
|
1.0
|
|
HB
|
B:VAL454
|
3.7
|
49.7
|
1.0
|
|
HE1
|
B:HIS474
|
3.9
|
52.7
|
1.0
|
|
CA
|
B:CYS455
|
4.1
|
37.7
|
1.0
|
|
HB2
|
B:CYS455
|
4.1
|
46.8
|
1.0
|
|
HB3
|
B:HIS472
|
4.2
|
49.9
|
1.0
|
|
N
|
B:HIS472
|
4.2
|
39.9
|
1.0
|
|
NE2
|
B:HIS472
|
4.3
|
41.2
|
1.0
|
|
H
|
B:VAL454
|
4.3
|
54.7
|
1.0
|
|
CE1
|
B:HIS474
|
4.3
|
43.9
|
1.0
|
|
CD2
|
B:HIS472
|
4.3
|
41.8
|
1.0
|
|
CA
|
B:CYS452
|
4.4
|
44.8
|
1.0
|
|
H
|
B:ASP457
|
4.4
|
55.5
|
1.0
|
|
H
|
B:LYS456
|
4.4
|
62.1
|
1.0
|
|
CA
|
B:HIS472
|
4.5
|
41.3
|
1.0
|
|
HB2
|
B:ASP457
|
4.6
|
60.2
|
1.0
|
|
CB
|
B:VAL454
|
4.7
|
41.4
|
1.0
|
|
HG12
|
B:VAL454
|
4.7
|
49.4
|
1.0
|
|
CA
|
B:CYS475
|
4.7
|
46.3
|
1.0
|
|
HA
|
B:CYS452
|
4.8
|
53.8
|
1.0
|
|
C
|
B:CYS455
|
4.8
|
37.6
|
1.0
|
|
NE2
|
B:HIS474
|
4.8
|
47.9
|
1.0
|
|
C
|
B:VAL454
|
4.8
|
42.3
|
1.0
|
|
N
|
B:LYS456
|
4.9
|
51.8
|
1.0
|
|
H
|
B:CYS475
|
4.9
|
58.3
|
1.0
|
|
HE2
|
B:HIS474
|
4.9
|
57.5
|
1.0
|
|
H
|
B:CYS452
|
4.9
|
51.5
|
1.0
|
|
HA
|
B:CYS455
|
4.9
|
45.2
|
1.0
|
|
C
|
B:CYS452
|
4.9
|
43.9
|
1.0
|
|
ND1
|
B:HIS474
|
4.9
|
48.6
|
1.0
|
|
N
|
B:VAL454
|
5.0
|
45.6
|
1.0
|
|
Zinc binding site 5 out
of 8 in 6q3m
Go back to
Zinc Binding Sites List in 6q3m
Zinc binding site 5 out
of 8 in the Structure of CHD4 PHD2 - Tandem Chromodomains
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Structure of CHD4 PHD2 - Tandem Chromodomains within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn701
b:50.4
occ:1.00
|
SG
|
C:CYS490
|
2.2
|
49.8
|
1.0
|
|
SG
|
C:CYS464
|
2.2
|
60.5
|
1.0
|
|
SG
|
C:CYS467
|
2.3
|
45.8
|
1.0
|
|
SG
|
C:CYS493
|
2.3
|
52.4
|
1.0
|
|
H
|
C:CYS490
|
3.0
|
54.3
|
1.0
|
|
HB2
|
C:CYS464
|
3.1
|
59.8
|
1.0
|
|
CB
|
C:CYS464
|
3.1
|
49.8
|
1.0
|
|
HB2
|
C:CYS493
|
3.1
|
56.7
|
1.0
|
|
HB3
|
C:CYS467
|
3.2
|
56.9
|
1.0
|
|
HB3
|
C:CYS490
|
3.2
|
53.1
|
1.0
|
|
HB3
|
C:CYS464
|
3.2
|
59.8
|
1.0
|
|
CB
|
C:CYS490
|
3.3
|
44.2
|
1.0
|
|
CB
|
C:CYS467
|
3.3
|
47.4
|
1.0
|
|
CB
|
C:CYS493
|
3.3
|
47.2
|
1.0
|
|
HG1
|
C:THR466
|
3.5
|
54.5
|
1.0
|
|
H
|
C:CYS493
|
3.5
|
59.4
|
1.0
|
|
H
|
C:CYS467
|
3.5
|
63.5
|
1.0
|
|
HB2
|
C:SER469
|
3.7
|
67.3
|
1.0
|
|
N
|
C:CYS467
|
3.8
|
52.9
|
1.0
|
|
N
|
C:CYS490
|
3.8
|
45.2
|
1.0
|
|
HB2
|
C:ARG492
|
3.9
|
59.2
|
1.0
|
|
OG1
|
C:THR466
|
4.0
|
45.4
|
1.0
|
|
N
|
C:CYS493
|
4.0
|
49.5
|
1.0
|
|
CA
|
C:CYS467
|
4.0
|
50.6
|
1.0
|
|
CA
|
C:CYS490
|
4.1
|
44.9
|
1.0
|
|
HB3
|
C:CYS493
|
4.1
|
56.7
|
1.0
|
|
HB2
|
C:CYS490
|
4.1
|
53.1
|
1.0
|
|
HB2
|
C:CYS467
|
4.1
|
56.9
|
1.0
|
|
H
|
C:THR466
|
4.1
|
55.5
|
1.0
|
|
CA
|
C:CYS493
|
4.3
|
48.0
|
1.0
|
|
H
|
C:SER469
|
4.3
|
65.6
|
1.0
|
|
HG
|
C:SER469
|
4.3
|
69.3
|
1.0
|
|
C
|
C:THR466
|
4.4
|
44.9
|
1.0
|
|
CA
|
C:CYS464
|
4.6
|
49.0
|
1.0
|
|
CB
|
C:SER469
|
4.6
|
56.1
|
1.0
|
|
C
|
C:CYS467
|
4.6
|
50.5
|
1.0
|
|
HA
|
C:CYS493
|
4.6
|
57.6
|
1.0
|
|
HA
|
C:LEU489
|
4.6
|
59.2
|
1.0
|
|
C
|
C:CYS490
|
4.6
|
44.7
|
1.0
|
|
O
|
C:CYS490
|
4.7
|
45.0
|
1.0
|
|
OG
|
C:SER469
|
4.7
|
57.8
|
1.0
|
|
O
|
C:CYS467
|
4.7
|
54.2
|
1.0
|
|
HA
|
C:CYS464
|
4.8
|
58.9
|
1.0
|
|
H
|
C:ARG492
|
4.8
|
71.2
|
1.0
|
|
N
|
C:THR466
|
4.9
|
46.3
|
1.0
|
|
CB
|
C:ARG492
|
4.9
|
49.3
|
1.0
|
|
HA
|
C:CYS467
|
4.9
|
60.8
|
1.0
|
|
HA
|
C:CYS490
|
4.9
|
53.9
|
1.0
|
|
C
|
C:LEU489
|
4.9
|
48.6
|
1.0
|
|
O
|
C:THR466
|
5.0
|
44.6
|
1.0
|
|
C
|
C:ARG492
|
5.0
|
56.1
|
1.0
|
|
Zinc binding site 6 out
of 8 in 6q3m
Go back to
Zinc Binding Sites List in 6q3m
Zinc binding site 6 out
of 8 in the Structure of CHD4 PHD2 - Tandem Chromodomains
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Structure of CHD4 PHD2 - Tandem Chromodomains within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn702
b:58.6
occ:1.00
|
ND1
|
C:HIS472
|
2.2
|
70.7
|
1.0
|
|
SG
|
C:CYS455
|
2.3
|
66.9
|
1.0
|
|
SG
|
C:CYS475
|
2.3
|
60.6
|
1.0
|
|
SG
|
C:CYS452
|
2.4
|
61.9
|
1.0
|
|
HB3
|
C:CYS452
|
2.7
|
66.3
|
1.0
|
|
HB2
|
C:HIS472
|
2.8
|
67.1
|
1.0
|
|
CB
|
C:CYS452
|
2.9
|
55.3
|
1.0
|
|
H
|
C:CYS455
|
2.9
|
61.9
|
1.0
|
|
HB2
|
C:CYS452
|
3.0
|
66.3
|
1.0
|
|
HB3
|
C:CYS455
|
3.1
|
65.3
|
1.0
|
|
CG
|
C:HIS472
|
3.1
|
58.4
|
1.0
|
|
CE1
|
C:HIS472
|
3.2
|
61.2
|
1.0
|
|
CB
|
C:CYS455
|
3.3
|
54.4
|
1.0
|
|
HB2
|
C:CYS475
|
3.3
|
70.1
|
1.0
|
|
HE1
|
C:HIS472
|
3.3
|
73.4
|
1.0
|
|
H
|
C:HIS472
|
3.4
|
65.9
|
1.0
|
|
CB
|
C:CYS475
|
3.4
|
58.4
|
1.0
|
|
CB
|
C:HIS472
|
3.4
|
55.9
|
1.0
|
|
HB3
|
C:CYS475
|
3.7
|
70.1
|
1.0
|
|
N
|
C:CYS455
|
3.7
|
51.6
|
1.0
|
|
HB
|
C:VAL454
|
3.7
|
65.0
|
1.0
|
|
HB2
|
C:CYS455
|
4.1
|
65.3
|
1.0
|
|
CA
|
C:CYS455
|
4.1
|
53.5
|
1.0
|
|
N
|
C:HIS472
|
4.1
|
54.9
|
1.0
|
|
HB3
|
C:HIS472
|
4.1
|
67.1
|
1.0
|
|
HE1
|
C:HIS474
|
4.1
|
85.5
|
1.0
|
|
NE2
|
C:HIS472
|
4.3
|
61.4
|
1.0
|
|
H
|
C:VAL454
|
4.3
|
63.7
|
1.0
|
|
CD2
|
C:HIS472
|
4.3
|
59.8
|
1.0
|
|
CA
|
C:HIS472
|
4.4
|
54.7
|
1.0
|
|
CA
|
C:CYS452
|
4.4
|
54.7
|
1.0
|
|
H
|
C:ASP457
|
4.4
|
77.9
|
1.0
|
|
H
|
C:LYS456
|
4.5
|
79.3
|
1.0
|
|
CE1
|
C:HIS474
|
4.6
|
71.2
|
1.0
|
|
CB
|
C:VAL454
|
4.6
|
54.2
|
1.0
|
|
CA
|
C:CYS475
|
4.8
|
59.1
|
1.0
|
|
HB2
|
C:ASP457
|
4.8
|
82.3
|
1.0
|
|
C
|
C:VAL454
|
4.8
|
55.2
|
1.0
|
|
H
|
C:CYS475
|
4.8
|
69.5
|
1.0
|
|
HA
|
C:CYS452
|
4.8
|
65.6
|
1.0
|
|
C
|
C:CYS455
|
4.9
|
54.1
|
1.0
|
|
C
|
C:CYS452
|
4.9
|
53.9
|
1.0
|
|
HG12
|
C:VAL454
|
4.9
|
61.1
|
1.0
|
|
HA
|
C:CYS455
|
4.9
|
64.1
|
1.0
|
|
N
|
C:VAL454
|
4.9
|
53.1
|
1.0
|
|
N
|
C:LYS456
|
4.9
|
66.0
|
1.0
|
|
H
|
C:CYS452
|
5.0
|
69.7
|
1.0
|
|
HA
|
C:TYR471
|
5.0
|
63.3
|
1.0
|
|
Zinc binding site 7 out
of 8 in 6q3m
Go back to
Zinc Binding Sites List in 6q3m
Zinc binding site 7 out
of 8 in the Structure of CHD4 PHD2 - Tandem Chromodomains
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Structure of CHD4 PHD2 - Tandem Chromodomains within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn701
b:61.5
occ:1.00
|
SG
|
D:CYS467
|
2.2
|
62.9
|
1.0
|
|
SG
|
D:CYS490
|
2.2
|
67.9
|
1.0
|
|
SG
|
D:CYS493
|
2.3
|
65.2
|
1.0
|
|
SG
|
D:CYS464
|
2.3
|
68.7
|
1.0
|
|
HG1
|
D:THR466
|
3.1
|
89.9
|
1.0
|
|
H
|
D:CYS490
|
3.2
|
85.1
|
1.0
|
|
HB3
|
D:CYS464
|
3.3
|
81.7
|
1.0
|
|
CB
|
D:CYS464
|
3.3
|
68.0
|
1.0
|
|
HB3
|
D:CYS490
|
3.3
|
83.4
|
1.0
|
|
HB2
|
D:CYS464
|
3.3
|
81.7
|
1.0
|
|
CB
|
D:CYS490
|
3.4
|
69.5
|
1.0
|
|
HB3
|
D:CYS467
|
3.4
|
63.9
|
1.0
|
|
CB
|
D:CYS467
|
3.5
|
53.3
|
1.0
|
|
HB2
|
D:SER469
|
3.5
|
79.6
|
1.0
|
|
HB2
|
D:CYS493
|
3.5
|
78.1
|
1.0
|
|
H
|
D:CYS493
|
3.6
|
76.5
|
1.0
|
|
CB
|
D:CYS493
|
3.6
|
65.1
|
1.0
|
|
OG1
|
D:THR466
|
3.7
|
74.9
|
1.0
|
|
H
|
D:CYS467
|
3.9
|
67.3
|
1.0
|
|
N
|
D:CYS490
|
3.9
|
70.9
|
1.0
|
|
HB2
|
D:ARG492
|
3.9
|
73.9
|
1.0
|
|
N
|
D:CYS467
|
4.0
|
56.0
|
1.0
|
|
N
|
D:CYS493
|
4.1
|
63.7
|
1.0
|
|
HB2
|
D:CYS490
|
4.2
|
83.4
|
1.0
|
|
HG
|
D:SER469
|
4.2
|
76.1
|
1.0
|
|
CA
|
D:CYS490
|
4.2
|
68.4
|
1.0
|
|
H
|
D:THR466
|
4.2
|
89.5
|
1.0
|
|
HB2
|
D:CYS467
|
4.2
|
63.9
|
1.0
|
|
CA
|
D:CYS467
|
4.3
|
54.4
|
1.0
|
|
H
|
D:SER469
|
4.3
|
79.0
|
1.0
|
|
HB3
|
D:CYS493
|
4.3
|
78.1
|
1.0
|
|
CB
|
D:SER469
|
4.3
|
66.3
|
1.0
|
|
OG
|
D:SER469
|
4.4
|
63.4
|
1.0
|
|
CA
|
D:CYS493
|
4.5
|
65.5
|
1.0
|
|
O
|
D:CYS490
|
4.6
|
67.7
|
1.0
|
|
C
|
D:THR466
|
4.6
|
66.6
|
1.0
|
|
C
|
D:CYS490
|
4.7
|
67.3
|
1.0
|
|
O
|
D:CYS467
|
4.7
|
57.7
|
1.0
|
|
C
|
D:CYS467
|
4.7
|
55.6
|
1.0
|
|
CA
|
D:CYS464
|
4.7
|
67.5
|
1.0
|
|
HA
|
D:CYS493
|
4.7
|
78.6
|
1.0
|
|
HA
|
D:LEU489
|
4.8
|
0.4
|
1.0
|
|
HB3
|
D:SER469
|
4.9
|
79.6
|
1.0
|
|
CB
|
D:ARG492
|
4.9
|
61.6
|
1.0
|
|
H
|
D:ARG492
|
4.9
|
80.1
|
1.0
|
|
HD3
|
D:ARG492
|
4.9
|
71.1
|
1.0
|
|
CB
|
D:THR466
|
5.0
|
71.3
|
1.0
|
|
N
|
D:THR466
|
5.0
|
74.5
|
1.0
|
|
Zinc binding site 8 out
of 8 in 6q3m
Go back to
Zinc Binding Sites List in 6q3m
Zinc binding site 8 out
of 8 in the Structure of CHD4 PHD2 - Tandem Chromodomains
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Structure of CHD4 PHD2 - Tandem Chromodomains within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn702
b:75.8
occ:1.00
|
HD1
|
D:HIS472
|
2.1
|
0.6
|
1.0
|
|
SG
|
D:CYS475
|
2.2
|
77.3
|
1.0
|
|
SG
|
D:CYS455
|
2.3
|
78.3
|
1.0
|
|
ND1
|
D:HIS472
|
2.4
|
89.7
|
1.0
|
|
SG
|
D:CYS452
|
2.4
|
78.5
|
1.0
|
|
HB3
|
D:CYS452
|
2.8
|
98.4
|
1.0
|
|
HB2
|
D:CYS452
|
2.9
|
98.4
|
1.0
|
|
CB
|
D:CYS452
|
2.9
|
82.0
|
1.0
|
|
HB2
|
D:HIS472
|
3.0
|
0.3
|
1.0
|
|
CG
|
D:HIS472
|
3.0
|
89.0
|
1.0
|
|
CE1
|
D:HIS472
|
3.0
|
88.1
|
1.0
|
|
H
|
D:CYS455
|
3.2
|
94.2
|
1.0
|
|
HB2
|
D:CYS475
|
3.3
|
91.0
|
1.0
|
|
HE1
|
D:HIS472
|
3.3
|
0.7
|
1.0
|
|
CB
|
D:CYS475
|
3.3
|
75.8
|
1.0
|
|
HB3
|
D:CYS455
|
3.4
|
95.0
|
1.0
|
|
CB
|
D:CYS455
|
3.5
|
79.1
|
1.0
|
|
CB
|
D:HIS472
|
3.5
|
88.6
|
1.0
|
|
HB3
|
D:CYS475
|
3.5
|
91.0
|
1.0
|
|
H
|
D:HIS472
|
3.6
|
0.6
|
1.0
|
|
HB
|
D:VAL454
|
3.7
|
86.3
|
1.0
|
|
N
|
D:CYS455
|
3.9
|
78.5
|
1.0
|
|
NE2
|
D:HIS472
|
3.9
|
90.0
|
1.0
|
|
CD2
|
D:HIS472
|
3.9
|
89.1
|
1.0
|
|
HE2
|
D:HIS474
|
4.2
|
0.4
|
1.0
|
|
HB3
|
D:HIS472
|
4.2
|
0.3
|
1.0
|
|
HB2
|
D:CYS455
|
4.2
|
95.0
|
1.0
|
|
CA
|
D:CYS455
|
4.2
|
79.4
|
1.0
|
|
H
|
D:ASP457
|
4.2
|
0.1
|
1.0
|
|
HB2
|
D:ASP457
|
4.3
|
0.0
|
1.0
|
|
N
|
D:HIS472
|
4.3
|
85.5
|
1.0
|
|
H
|
D:LYS456
|
4.4
|
88.7
|
1.0
|
|
CA
|
D:CYS452
|
4.4
|
81.1
|
1.0
|
|
NE2
|
D:HIS474
|
4.5
|
93.7
|
1.0
|
|
CA
|
D:HIS472
|
4.6
|
87.1
|
1.0
|
|
HE2
|
D:HIS472
|
4.6
|
1.0
|
1.0
|
|
H
|
D:VAL454
|
4.6
|
85.3
|
1.0
|
|
HG12
|
D:VAL454
|
4.6
|
87.7
|
1.0
|
|
CB
|
D:VAL454
|
4.6
|
71.9
|
1.0
|
|
HD2
|
D:HIS472
|
4.7
|
0.9
|
1.0
|
|
CA
|
D:CYS475
|
4.7
|
75.4
|
1.0
|
|
H
|
D:CYS475
|
4.7
|
96.7
|
1.0
|
|
HA
|
D:CYS452
|
4.8
|
97.3
|
1.0
|
|
N
|
D:LYS456
|
4.9
|
73.9
|
1.0
|
|
C
|
D:CYS455
|
4.9
|
79.3
|
1.0
|
|
O
|
D:ASP457
|
4.9
|
82.1
|
1.0
|
|
HA
|
D:CYS475
|
5.0
|
90.5
|
1.0
|
|
C
|
D:VAL454
|
5.0
|
72.7
|
1.0
|
|
Reference:
E.J.Mancini,
A.Alt.
Structure of Histone Readers To Be Published.
Page generated: Tue Oct 29 05:31:10 2024
|
