Zinc in PDB 6q0v: Structure of DDB1-DDA1-DCAF15 Complex Bound to Tasisulam and RBM39

Protein crystallography data

The structure of Structure of DDB1-DDA1-DCAF15 Complex Bound to Tasisulam and RBM39, PDB code: 6q0v was solved by T.Faust, H.Yoon, R.P.Nowak, K.A.Donovan, Z.Li, Q.Cai, N.A.Eleuteri, T.Zhang, N.S.Gray, E.S.Fischer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.55 / 2.90
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 81.769, 94.613, 260.390, 90.00, 90.00, 90.00
R / Rfree (%) 20.6 / 24.2

Other elements in 6q0v:

The structure of Structure of DDB1-DDA1-DCAF15 Complex Bound to Tasisulam and RBM39 also contains other interesting chemical elements:

Bromine (Br) 1 atom
Chlorine (Cl) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of DDB1-DDA1-DCAF15 Complex Bound to Tasisulam and RBM39 (pdb code 6q0v). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of DDB1-DDA1-DCAF15 Complex Bound to Tasisulam and RBM39, PDB code: 6q0v:

Zinc binding site 1 out of 1 in 6q0v

Go back to Zinc Binding Sites List in 6q0v
Zinc binding site 1 out of 1 in the Structure of DDB1-DDA1-DCAF15 Complex Bound to Tasisulam and RBM39


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of DDB1-DDA1-DCAF15 Complex Bound to Tasisulam and RBM39 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn302

b:0.1
occ:1.00
SG B:CYS211 2.1 0.4 1.0
SG B:CYS196 2.2 0.7 1.0
SG B:CYS193 2.2 0.6 1.0
ND1 B:HIS214 2.6 0.9 1.0
CB B:CYS193 3.3 0.8 1.0
CB B:CYS196 3.3 0.5 1.0
CB B:HIS214 3.3 0.2 1.0
CG B:HIS214 3.3 0.8 1.0
CB B:CYS211 3.6 0.0 1.0
CE1 B:HIS214 3.7 0.7 1.0
N B:CYS196 3.7 0.7 1.0
CA B:CYS196 3.9 0.0 1.0
N B:HIS214 4.2 0.3 1.0
N B:CYS211 4.3 1.0 1.0
CA B:HIS214 4.4 0.2 1.0
CA B:CYS211 4.4 0.7 1.0
C B:ALA195 4.5 0.4 1.0
CD2 B:HIS214 4.6 0.2 1.0
CB B:ALA195 4.7 0.8 1.0
CA B:CYS193 4.7 0.5 1.0
NE2 B:HIS214 4.7 0.2 1.0
O B:CYS211 4.9 0.9 1.0
CB B:PRO189 4.9 0.8 1.0
C B:CYS211 4.9 0.3 1.0

Reference:

T.B.Faust, H.Yoon, R.P.Nowak, K.A.Donovan, Z.Li, Q.Cai, N.A.Eleuteri, T.Zhang, N.S.Gray, E.S.Fischer. Structural Complementarity Facilitates E7820-Mediated Degradation of RBM39 By DCAF15. Nat.Chem.Biol. 2019.
ISSN: ESSN 1552-4469
PubMed: 31686031
DOI: 10.1038/S41589-019-0378-3
Page generated: Wed Dec 16 12:33:23 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy