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Zinc in PDB 6nh7: Structure of Human Endothelial Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-2,5,6- Trifluorophenethyl)-4-Methylpyridin-2-AmineProtein crystallography data
The structure of Structure of Human Endothelial Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-2,5,6- Trifluorophenethyl)-4-Methylpyridin-2-Amine, PDB code: 6nh7
was solved by
G.Chreifi,
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6nh7:
The structure of Structure of Human Endothelial Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-2,5,6- Trifluorophenethyl)-4-Methylpyridin-2-Amine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Human Endothelial Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-2,5,6- Trifluorophenethyl)-4-Methylpyridin-2-Amine
(pdb code 6nh7). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Human Endothelial Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-2,5,6- Trifluorophenethyl)-4-Methylpyridin-2-Amine, PDB code: 6nh7: Zinc binding site 1 out of 1 in 6nh7Go back to![]() ![]()
Zinc binding site 1 out
of 1 in the Structure of Human Endothelial Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-2,5,6- Trifluorophenethyl)-4-Methylpyridin-2-Amine
![]() Mono view ![]() Stereo pair view
Reference:
H.T.Do,
H.Li,
G.Chreifi,
T.L.Poulos,
R.B.Silverman.
Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having A 2-Aminopyridine Scaffold. J. Med. Chem. V. 62 2690 2019.
Page generated: Wed Dec 16 12:23:32 2020
ISSN: ISSN 1520-4804 PubMed: 30802056 DOI: 10.1021/ACS.JMEDCHEM.8B02032 |
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