Zinc in PDB 6n7h: Cryo-Em Structure of the 2:1 HPTCH1-Shhp Complex

The structure of Cryo-Em Structure of the 2:1 HPTCH1-Shhp Complex also contains other interesting chemical elements:

Calcium

(Ca)

2 atoms

The binding sites of Zinc atom in the Cryo-Em Structure of the 2:1 HPTCH1-Shhp Complex (pdb code 6n7h). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of the 2:1 HPTCH1-Shhp Complex, PDB code: 6n7h:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of the 2:1 HPTCH1-Shhp Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of the 2:1 HPTCH1-Shhp Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn202 b:78.4 occ:1.00 OD2 C:ASP147 2.1 55.0 1.0 NE2 C:HIS140 2.1 62.3 1.0 ND1 C:HIS182 2.2 51.6 1.0 OD1 C:ASP147 2.2 55.0 1.0 CG C:ASP147 2.5 55.0 1.0 CE1 C:HIS182 2.6 51.6 1.0 CD2 C:HIS140 2.9 62.3 1.0 CE1 C:HIS140 3.3 62.3 1.0 CG C:HIS182 3.5 51.6 1.0 OE1 C:GLU176 3.7 53.2 1.0 NE2 C:HIS182 3.9 51.6 1.0 CB C:ASP147 4.0 55.0 1.0 CG C:HIS140 4.1 62.3 1.0 CB C:HIS182 4.2 51.6 1.0 ND1 C:HIS140 4.3 62.3 1.0 CD2 C:HIS182 4.3 51.6 1.0 CA C:HIS182 4.7 51.6 1.0 CA C:ASP147 4.8 55.0 1.0 CD C:GLU176 4.8 53.2 1.0 CE1 C:HIS180 4.8 47.4 1.0 N C:ASP147 4.9 55.0 1.0

H.Qian, P.Cao, M.Hu, S.Gao, N.Yan, X.Gong. Inhibition of Tetrameric PATCHED1 By Sonic Hedgehog Through An Asymmetric Paradigm. Nat Commun V. 10 2320 2019.
ISSN: ESSN 2041-1723
PubMed: 31127104
DOI: 10.1038/S41467-019-10234-9