Zinc in PDB 6n36: Beta-Lactamase From Chitinophaga Pinensis

All present enzymatic activity of Beta-Lactamase From Chitinophaga Pinensis:
3.5.2.6;

The structure of Beta-Lactamase From Chitinophaga Pinensis, PDB code: 6n36 was solved by J.Osipiuk, C.Tesar, M.Endres, A.Joachimiak, Center For Structuralgenomics Of Infectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.78 / 1.45
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	40.137, 79.849, 85.488, 90.00, 90.00, 90.00
R / Rfree (%)	15.6 / 18.5

The binding sites of Zinc atom in the Beta-Lactamase From Chitinophaga Pinensis (pdb code 6n36). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Beta-Lactamase From Chitinophaga Pinensis, PDB code: 6n36:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Beta-Lactamase From Chitinophaga Pinensis


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Beta-Lactamase From Chitinophaga Pinensis within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:22.0 occ:0.90 O A:HOH783 2.0 27.5 1.0 NE2 A:HIS249 2.1 19.3 1.0 OD2 A:ASP110 2.1 21.5 1.0 NE2 A:HIS111 2.1 19.1 1.0 O A:HOH603 2.6 29.7 1.0 CG A:ASP110 3.0 23.0 1.0 CE1 A:HIS249 3.0 20.4 1.0 CE1 A:HIS111 3.0 18.5 1.0 O A:HOH791 3.1 57.0 1.0 CD2 A:HIS111 3.1 17.5 1.0 CD2 A:HIS249 3.1 20.0 1.0 OD1 A:ASP110 3.2 21.4 1.0 ZN A:ZN502 3.5 21.9 0.9 NE2 A:HIS106 3.9 19.2 1.0 CE1 A:HIS106 4.0 18.1 1.0 ND1 A:HIS249 4.2 21.2 1.0 ND1 A:HIS111 4.2 18.2 1.0 O A:HOH737 4.2 31.5 1.0 CG A:HIS111 4.2 17.9 1.0 O A:HOH772 4.2 28.9 1.0 CG A:HIS249 4.2 20.0 1.0 CB A:ASP110 4.3 21.4 1.0 O A:HOH804 4.6 49.8 1.0

Zinc binding site 2 out of 2 in the Beta-Lactamase From Chitinophaga Pinensis


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Beta-Lactamase From Chitinophaga Pinensis within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn502 b:21.9 occ:0.90 O A:HOH603 2.0 29.7 1.0 ND1 A:HIS108 2.1 20.0 1.0 NE2 A:HIS183 2.1 18.6 1.0 NE2 A:HIS106 2.2 19.2 1.0 O A:HOH772 2.3 28.9 1.0 O A:HOH783 2.4 27.5 1.0 CE1 A:HIS108 3.0 20.5 1.0 CD2 A:HIS183 3.1 20.4 1.0 CE1 A:HIS106 3.1 18.1 1.0 CE1 A:HIS183 3.1 19.7 1.0 CG A:HIS108 3.2 19.3 1.0 CD2 A:HIS106 3.2 18.7 1.0 ZN A:ZN501 3.5 22.0 0.9 CB A:HIS108 3.6 19.3 1.0 O A:HOH791 3.8 57.0 1.0 NE2 A:HIS108 4.2 21.3 1.0 ND1 A:HIS106 4.2 20.2 1.0 OD1 A:ASP110 4.2 21.4 1.0 CG A:HIS183 4.2 18.7 1.0 ND1 A:HIS183 4.2 20.6 1.0 CD2 A:HIS108 4.3 21.7 1.0 CG A:HIS106 4.3 17.8 1.0 NE2 A:HIS111 4.4 19.1 1.0 CD2 A:HIS111 4.4 17.5 1.0 O A:HOH737 4.5 31.5 1.0 O A:HOH729 4.8 31.2 1.0 OD2 A:ASP110 4.8 21.5 1.0 CG A:ASP110 4.9 23.0 1.0

J.Osipiuk, C.Tesar, M.Endres, A.Joachimiak, Center For Structural Genomics Of Infectious Diseases(Csgid). Beta-Lactamase From Chitinophaga Pinensis To Be Published.