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Zinc in PDB 6kqp: NSD1 Set Domain in Complex with SamEnzymatic activity of NSD1 Set Domain in Complex with Sam
All present enzymatic activity of NSD1 Set Domain in Complex with Sam:
2.1.1.357; Protein crystallography data
The structure of NSD1 Set Domain in Complex with Sam, PDB code: 6kqp
was solved by
H.J.Cho,
T.Cierpicki,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the NSD1 Set Domain in Complex with Sam
(pdb code 6kqp). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the NSD1 Set Domain in Complex with Sam, PDB code: 6kqp: Jump to Zinc binding site number: 1; 2; 3; Zinc binding site 1 out of 3 in 6kqpGo back to Zinc Binding Sites List in 6kqp
Zinc binding site 1 out
of 3 in the NSD1 Set Domain in Complex with Sam
Mono view Stereo pair view
Zinc binding site 2 out of 3 in 6kqpGo back to Zinc Binding Sites List in 6kqp
Zinc binding site 2 out
of 3 in the NSD1 Set Domain in Complex with Sam
Mono view Stereo pair view
Zinc binding site 3 out of 3 in 6kqpGo back to Zinc Binding Sites List in 6kqp
Zinc binding site 3 out
of 3 in the NSD1 Set Domain in Complex with Sam
Mono view Stereo pair view
Reference:
H.Huang,
C.A.Howard,
S.Zari,
H.J.Cho,
S.Shukla,
H.Li,
J.Ndoj,
P.Gonzalez-Alonso,
C.Nikolaidis,
J.Abbott,
D.S.Rogawski,
M.A.Potopnyk,
K.Kempinska,
H.Miao,
T.Purohit,
A.Henderson,
A.Mapp,
M.L.Sulis,
A.Ferrando,
J.Grembecka,
T.Cierpicki.
Covalent Inhibition of NSD1 Histone Methyltransferase. Nat.Chem.Biol. V. 16 1403 2020.
Page generated: Wed Dec 16 12:09:21 2020
ISSN: ESSN 1552-4469 PubMed: 32868895 DOI: 10.1038/S41589-020-0626-6 |
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