Zinc in PDB 6kan: Crystal Structure of Fkrp in Complex with Ba Ion

The structure of Crystal Structure of Fkrp in Complex with Ba Ion, PDB code: 6kan was solved by N.Kuwabara, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.92 / 2.25
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	77.073, 119.051, 257.563, 90.00, 90.00, 90.00
R / Rfree (%)	19.6 / 23.2

The structure of Crystal Structure of Fkrp in Complex with Ba Ion also contains other interesting chemical elements:

Barium

(Ba)

5 atoms

The binding sites of Zinc atom in the Crystal Structure of Fkrp in Complex with Ba Ion (pdb code 6kan). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of Fkrp in Complex with Ba Ion, PDB code: 6kan:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Crystal Structure of Fkrp in Complex with Ba Ion


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Fkrp in Complex with Ba Ion within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:40.5 occ:1.00 SG A:CYS317 2.3 36.6 1.0 SG A:CYS318 2.4 39.5 1.0 SG A:CYS289 2.4 43.9 1.0 SG A:CYS296 2.4 39.4 1.0 N A:CYS318 3.1 41.4 1.0 CB A:CYS289 3.3 40.4 1.0 CB A:CYS317 3.4 39.0 1.0 CB A:CYS296 3.4 35.3 1.0 CB A:CYS318 3.5 41.6 1.0 CA A:CYS318 3.6 41.4 1.0 N A:CYS289 3.6 40.2 1.0 C A:CYS317 3.6 39.7 1.0 N A:CYS296 3.8 39.8 1.0 CB A:PRO315 4.0 34.2 1.0 CA A:CYS289 4.0 41.8 1.0 CA A:CYS317 4.1 40.4 1.0 CA A:CYS296 4.2 39.1 1.0 O A:CYS317 4.4 35.1 1.0 N A:CYS317 4.5 36.9 1.0 C A:GLY288 4.6 39.8 1.0 CG A:PRO315 4.7 34.4 1.0 C A:CYS289 4.8 43.5 1.0 CA A:GLY288 4.8 37.1 1.0 O A:CYS289 4.9 42.6 1.0 C A:ARG295 4.9 40.1 1.0

Zinc binding site 2 out of 4 in the Crystal Structure of Fkrp in Complex with Ba Ion


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Fkrp in Complex with Ba Ion within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn501 b:46.7 occ:1.00 SG B:CYS318 2.3 43.3 1.0 SG B:CYS289 2.3 55.3 1.0 SG B:CYS317 2.4 44.0 1.0 SG B:CYS296 2.5 42.0 1.0 N B:CYS318 3.0 37.6 1.0 CB B:CYS289 3.0 51.1 1.0 CB B:CYS318 3.4 40.3 1.0 CA B:CYS318 3.5 38.9 1.0 CB B:CYS317 3.5 46.1 1.0 CB B:CYS296 3.6 43.3 1.0 N B:CYS289 3.6 51.2 1.0 C B:CYS317 3.7 39.3 1.0 CA B:CYS289 3.8 49.9 1.0 N B:CYS296 4.0 53.8 1.0 CB B:PRO315 4.1 35.5 1.0 CA B:CYS317 4.1 42.1 1.0 CA B:CYS296 4.4 47.5 1.0 O B:CYS317 4.5 40.3 1.0 N B:CYS317 4.5 43.8 1.0 CG B:PRO315 4.7 37.4 1.0 C B:GLY288 4.7 51.5 1.0 NE B:ARG275 4.9 43.4 1.0 CA B:GLY288 4.9 48.5 1.0 O B:PRO315 5.0 48.1 1.0

Zinc binding site 3 out of 4 in the Crystal Structure of Fkrp in Complex with Ba Ion


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of Fkrp in Complex with Ba Ion within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn501 b:39.9 occ:1.00 SG C:CYS317 2.3 36.8 1.0 SG C:CYS318 2.4 36.9 1.0 SG C:CYS296 2.4 40.2 1.0 SG C:CYS289 2.4 40.7 1.0 N C:CYS318 3.1 34.2 1.0 CB C:CYS289 3.3 41.4 1.0 CB C:CYS296 3.4 39.9 1.0 CB C:CYS317 3.4 37.7 1.0 CB C:CYS318 3.6 31.0 1.0 CA C:CYS318 3.6 33.6 1.0 C C:CYS317 3.6 36.9 1.0 N C:CYS289 3.7 40.3 1.0 N C:CYS296 3.9 42.8 1.0 CB C:PRO315 4.0 35.7 1.0 CA C:CYS317 4.1 37.1 1.0 CA C:CYS289 4.1 40.9 1.0 CA C:CYS296 4.2 41.7 1.0 O C:CYS317 4.3 32.4 1.0 N C:CYS317 4.5 35.1 1.0 CG C:PRO315 4.8 30.6 1.0 C C:GLY288 4.8 41.3 1.0 O C:PRO315 4.9 35.8 1.0 C C:CYS289 4.9 43.6 1.0 NE C:ARG275 4.9 34.5 1.0 C C:ARG295 5.0 40.1 1.0 CA C:GLY288 5.0 36.0 1.0

Zinc binding site 4 out of 4 in the Crystal Structure of Fkrp in Complex with Ba Ion


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of Fkrp in Complex with Ba Ion within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn501 b:45.4 occ:1.00 SG D:CYS317 2.3 40.7 1.0 SG D:CYS318 2.3 44.4 1.0 SG D:CYS289 2.4 41.4 1.0 SG D:CYS296 2.5 44.0 1.0 N D:CYS318 3.0 35.2 1.0 CB D:CYS289 3.3 42.6 1.0 CB D:CYS318 3.5 41.5 1.0 CA D:CYS318 3.5 38.1 1.0 CB D:CYS317 3.5 37.8 1.0 CB D:CYS296 3.5 47.6 1.0 C D:CYS317 3.6 38.2 1.0 N D:CYS289 3.7 40.3 1.0 N D:CYS296 3.9 52.4 1.0 CA D:CYS317 4.0 38.5 1.0 CB D:PRO315 4.1 42.5 1.0 CA D:CYS289 4.1 42.7 1.0 O D:CYS317 4.2 38.4 1.0 CA D:CYS296 4.3 53.5 1.0 N D:CYS317 4.5 43.0 1.0 O D:PRO315 4.8 42.6 1.0 CG D:PRO315 4.8 44.0 1.0 C D:CYS289 4.8 43.9 1.0 C D:GLY288 4.9 40.8 1.0 C D:ARG295 4.9 51.4 1.0 O D:CYS289 4.9 43.2 1.0 CA D:ARG295 5.0 49.9 1.0

K.Kobayashi, M.Kanagawa, H.Tsumoto, R.Kato, H.Manya, T.Endo, T.Senda, T.Toda, N.Kuwabara, R.Imae, T.Tanaka, M.Mizuno. Crystal Structures of Fukutin-Related Protein (Fkrp), A Ribitol-Phosphate Transferase Related to Muscular Dystrophy Nat Commun 2020.
ISSN: ESSN 2041-1723
DOI: 10.1038/S41467-019-14220-Z