Zinc in PDB 6hu9: III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae

All present enzymatic activity of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae:
1.10.2.2; 1.9.3.1;

The structure of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Iron	(Fe)	14 atoms
Calcium	(Ca)	2 atoms
Copper	(Cu)	6 atoms

The binding sites of Zinc atom in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae (pdb code 6hu9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae, PDB code: 6hu9:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ d:Zn201 b:65.6 occ:1.00 SG d:CYS137 2.4 45.5 1.0 SG d:CYS134 2.5 42.2 1.0 CE1 d:HIS119 2.5 44.3 1.0 SG d:CYS111 2.7 45.5 1.0 NE2 d:HIS119 2.9 44.3 1.0 CB d:CYS111 3.2 45.5 1.0 CB d:CYS134 3.2 42.2 1.0 CB d:CYS137 3.6 45.5 1.0 ND1 d:HIS119 3.8 44.3 1.0 C d:CYS111 4.0 45.5 1.0 OG d:SER139 4.1 45.8 1.0 N d:CYS137 4.1 45.5 1.0 N d:GLY113 4.1 49.9 1.0 N d:THR112 4.2 48.7 1.0 CA d:CYS111 4.2 45.5 1.0 O d:CYS111 4.2 45.5 1.0 CD2 d:HIS119 4.3 44.3 1.0 CA d:CYS137 4.4 45.5 1.0 CA d:GLY113 4.5 49.9 1.0 CB d:SER139 4.5 45.8 1.0 C d:THR112 4.6 48.7 1.0 CA d:CYS134 4.6 42.2 1.0 CA d:THR112 4.7 48.7 1.0 CG d:HIS119 4.7 44.3 1.0 CB d:MET122 4.9 39.6 1.0 N d:SER139 5.0 45.8 1.0

Zinc binding site 2 out of 2 in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ p:Zn201 b:65.0 occ:1.00 SG p:CYS134 2.5 43.2 1.0 SG p:CYS137 2.5 46.6 1.0 CE1 p:HIS119 2.6 43.7 1.0 SG p:CYS111 3.0 44.0 1.0 NE2 p:HIS119 3.1 43.7 1.0 CB p:CYS111 3.2 44.0 1.0 CB p:CYS137 3.4 46.6 1.0 CB p:CYS134 3.4 43.2 1.0 ND1 p:HIS119 3.8 43.7 1.0 N p:CYS137 3.9 46.6 1.0 C p:CYS111 3.9 44.0 1.0 N p:GLY113 4.1 48.4 1.0 O p:CYS111 4.1 44.0 1.0 N p:THR112 4.2 47.8 1.0 CA p:CYS137 4.2 46.6 1.0 CA p:CYS111 4.2 44.0 1.0 C p:THR112 4.3 47.8 1.0 CA p:GLY113 4.4 48.4 1.0 CD2 p:HIS119 4.5 43.7 1.0 CA p:THR112 4.5 47.8 1.0 OG p:SER139 4.5 45.0 1.0 CB p:SER139 4.8 45.0 1.0 CA p:CYS134 4.8 43.2 1.0 CG p:HIS119 4.8 43.7 1.0 N p:GLY138 4.8 45.1 1.0 C p:CYS137 4.9 46.6 1.0 O p:THR112 4.9 47.8 1.0 CB p:MET122 4.9 39.1 1.0 C p:GLU136 5.0 44.9 1.0 N p:SER139 5.0 45.0 1.0

A.M.Hartley, N.Lukoyanova, Y.Zhang, A.Cabrera-Orefice, S.Arnold, B.Meunier, N.Pinotsis, A.Marechal. Structure of Yeast Cytochrome C Oxidase in A Supercomplex with Cytochrome BC1. Nat. Struct. Mol. Biol. V. 26 78 2019.
ISSN: ESSN 1545-9985
PubMed: 30598554
DOI: 10.1038/S41594-018-0172-Z