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Zinc in PDB 6hoy: Human SIRT6 in Complex with Adp-Ribose and the Inhibitor Trichostatin AProtein crystallography data
The structure of Human SIRT6 in Complex with Adp-Ribose and the Inhibitor Trichostatin A, PDB code: 6hoy
was solved by
W.You,
C.Steegborn,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Human SIRT6 in Complex with Adp-Ribose and the Inhibitor Trichostatin A
(pdb code 6hoy). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Human SIRT6 in Complex with Adp-Ribose and the Inhibitor Trichostatin A, PDB code: 6hoy: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 6hoyGo back to Zinc Binding Sites List in 6hoy
Zinc binding site 1 out
of 2 in the Human SIRT6 in Complex with Adp-Ribose and the Inhibitor Trichostatin A
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 6hoyGo back to Zinc Binding Sites List in 6hoy
Zinc binding site 2 out
of 2 in the Human SIRT6 in Complex with Adp-Ribose and the Inhibitor Trichostatin A
Mono view Stereo pair view
Reference:
W.You,
C.Steegborn.
Structural Basis of Sirtuin 6 Inhibition By the Hydroxamate Trichostatin A: Implications For Protein Deacylase Drug Development. J.Med.Chem. V. 61 10922 2018.
Page generated: Wed Dec 16 11:57:39 2020
ISSN: ISSN 0022-2623 PubMed: 30395713 DOI: 10.1021/ACS.JMEDCHEM.8B01455 |
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