Zinc in PDB 6hdb: Crystal Structure of the Potassium Channel MTTMEM175 with Zinc

The structure of Crystal Structure of the Potassium Channel MTTMEM175 with Zinc, PDB code: 6hdb was solved by J.D.Brunner, R.P.Jakob, T.Schulze, Y.Neldner, A.Moroni, G.Thiel, T.Maier, S.Schenck, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.10 / 2.90
Space group	P 4 21 2
Cell size a, b, c (Å), α, β, γ (°)	131.920, 131.920, 132.790, 90.00, 90.00, 90.00
R / Rfree (%)	27.5 / 28.6

The structure of Crystal Structure of the Potassium Channel MTTMEM175 with Zinc also contains other interesting chemical elements:

Potassium

(K)

2 atoms

The binding sites of Zinc atom in the Crystal Structure of the Potassium Channel MTTMEM175 with Zinc (pdb code 6hdb). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Potassium Channel MTTMEM175 with Zinc, PDB code: 6hdb:

Zinc binding site 1 out of 1 in the Crystal Structure of the Potassium Channel MTTMEM175 with Zinc


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Potassium Channel MTTMEM175 with Zinc within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn504 b:0.4 occ:0.05 HD21 B:LEU39 3.1 0.7 1.0 HD21 B:LEU35 3.2 0.6 1.0 HD22 B:LEU35 3.4 0.9 1.0 HD11 B:LEU39 3.6 0.5 1.0 CD2 B:LEU35 3.6 0.4 1.0 HD23 B:LEU35 3.7 0.2 1.0 CD2 B:LEU39 4.1 0.3 1.0 CD1 B:LEU39 4.4 0.1 1.0 HG B:LEU39 4.5 0.7 1.0 HD23 B:LEU39 4.5 0.3 1.0 HD12 B:LEU39 4.7 0.9 1.0 CG B:LEU39 4.7 0.9 1.0 HD22 B:LEU39 4.8 0.1 1.0

J.D.Brunner, R.P.Jakob, T.Schulze, Y.Neldner, A.Moroni, G.Thiel, T.Maier, S.Schenck. Structural Basis For Ion Selectivity in TMEM175 K+ Channels Biorxiv 2019.
DOI: 10.1101/480863