Zinc in PDB 6gkh: Cryoem Structure of the MDA5-Dsrna Filament in Complex with Adp-ALF4

All present enzymatic activity of Cryoem Structure of the MDA5-Dsrna Filament in Complex with Adp-ALF4:
3.6.4.13;

The structure of Cryoem Structure of the MDA5-Dsrna Filament in Complex with Adp-ALF4 also contains other interesting chemical elements:

Fluorine	(F)	4 atoms
Magnesium	(Mg)	1 atom
Aluminium	(Al)	1 atom

The binding sites of Zinc atom in the Cryoem Structure of the MDA5-Dsrna Filament in Complex with Adp-ALF4 (pdb code 6gkh). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryoem Structure of the MDA5-Dsrna Filament in Complex with Adp-ALF4, PDB code: 6gkh:

Zinc binding site 1 out of 1 in the Cryoem Structure of the MDA5-Dsrna Filament in Complex with Adp-ALF4


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryoem Structure of the MDA5-Dsrna Filament in Complex with Adp-ALF4 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1104 b:0.7 occ:1.00 HG A:CYS907 1.1 0.6 1.0 SG A:CYS962 2.2 0.4 1.0 SG A:CYS910 2.3 0.4 1.0 SG A:CYS907 2.3 0.6 1.0 SG A:CYS964 2.3 0.1 1.0 HG A:CYS910 2.4 0.4 1.0 HE2 A:MET912 2.8 0.5 1.0 HB2 A:CYS907 3.0 0.6 1.0 CB A:CYS907 3.0 0.6 1.0 HB3 A:CYS907 3.1 0.6 1.0 HZ2 A:TRP968 3.2 0.4 1.0 CB A:CYS962 3.3 0.4 1.0 H A:CYS964 3.4 0.1 1.0 HB3 A:GLN966 3.4 0.7 1.0 H A:CYS910 3.5 0.4 1.0 HE1 A:TRP968 3.5 0.4 1.0 CB A:CYS964 3.5 0.1 1.0 CE A:MET912 3.6 0.5 1.0 HE1 A:MET912 3.7 0.5 1.0 HB3 A:MET912 3.7 0.5 1.0 CB A:CYS910 3.9 0.4 1.0 HB2 A:GLN966 3.9 0.7 1.0 H A:GLN966 4.0 0.7 1.0 HB3 A:CYS910 4.0 0.4 1.0 CZ2 A:TRP968 4.0 0.4 1.0 CB A:GLN966 4.1 0.7 1.0 N A:CYS964 4.2 0.1 1.0 NE1 A:TRP968 4.2 0.4 1.0 HB3 A:ASN909 4.2 0.3 1.0 N A:CYS910 4.2 0.4 1.0 HE3 A:MET912 4.2 0.5 1.0 H A:LYS963 4.3 0.5 1.0 HB2 A:MET912 4.4 0.5 1.0 H A:GLY965 4.5 0.1 1.0 CA A:CYS964 4.5 0.1 1.0 CE2 A:TRP968 4.5 0.4 1.0 CA A:CYS907 4.5 0.6 1.0 CB A:MET912 4.5 0.5 1.0 HB2 A:CYS910 4.5 0.4 1.0 O A:CYS910 4.5 0.4 1.0 CA A:CYS910 4.5 0.4 1.0 SD A:MET912 4.7 0.5 1.0 HG2 A:GLN966 4.7 0.7 1.0 CA A:CYS962 4.7 0.4 1.0 H A:MET912 4.7 0.5 1.0 HA A:CYS907 4.8 0.6 1.0 H A:LYS908 4.8 0.8 1.0 N A:LYS963 4.8 0.5 1.0 N A:GLN966 4.8 0.7 1.0 H A:ASN909 4.9 0.3 1.0 C A:CYS910 4.9 0.4 1.0 HA A:CYS962 4.9 0.4 1.0

Q.Yu, K.Qu, Y.Modis. Cryo-Em Structures of MDA5-Dsrna Filaments at Different Stages of Atp Hydrolysis. Mol. Cell V. 72 999 2018.
ISSN: ISSN 1097-4164
PubMed: 30449722
DOI: 10.1016/J.MOLCEL.2018.10.012