Zinc in PDB 6fvs: The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Barium Ions (BA2+)

The structure of The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Barium Ions (BA2+), PDB code: 6fvs was solved by H.Hu, M.Delarue, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 3.20
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	218.840, 112.110, 144.080, 90.00, 112.79, 90.00
R / Rfree (%)	20.8 / 22.6

The structure of The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Barium Ions (BA2+) also contains other interesting chemical elements:

Barium

(Ba)

2 atoms

The binding sites of Zinc atom in the The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Barium Ions (BA2+) (pdb code 6fvs). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Barium Ions (BA2+), PDB code: 6fvs:

Zinc binding site 1 out of 1 in the The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Barium Ions (BA2+)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Barium Ions (BA2+) within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn401 b:0.9 occ:1.00 OE1 D:GLU98 1.8 74.3 1.0 NE2 D:HIS49 1.9 81.8 1.0 CD D:GLU98 2.4 0.7 1.0 OE2 D:GLU98 2.5 0.1 1.0 CD2 D:HIS49 2.8 79.5 1.0 CE1 D:HIS49 2.9 82.3 1.0 CG D:GLU98 3.9 84.0 1.0 CG D:HIS49 4.0 77.6 1.0 ND1 D:HIS49 4.0 80.9 1.0 CG D:LYS55 4.1 76.7 1.0 CB D:GLU98 4.5 69.8 1.0 CD D:LYS55 4.6 81.2 1.0

H.Hu, A.Nemecz, C.Van Renterghem, Z.Fourati, L.Sauguet, P.J.Corringer, M.Delarue. Crystal Structures of A Pentameric Ion Channel Gated By Alkaline pH Show A Widely Open Pore and Identify A Cavity For Modulation. Proc. Natl. Acad. Sci. V. 115 E3959 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 29632192
DOI: 10.1073/PNAS.1717700115