Zinc in PDB 6e33: Crystal Structure of PHO7-Dna Complex

The structure of Crystal Structure of PHO7-Dna Complex, PDB code: 6e33 was solved by A.Garg, Y.Goldgur, S.Shuman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.13 / 1.71
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	50.827, 40.682, 58.237, 90.00, 105.84, 90.00
R / Rfree (%)	18.8 / 21.5

The binding sites of Zinc atom in the Crystal Structure of PHO7-Dna Complex (pdb code 6e33). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of PHO7-Dna Complex, PDB code: 6e33:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of PHO7-Dna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of PHO7-Dna Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:24.2 occ:1.00 SG A:CYS318 2.2 24.9 1.0 SG A:CYS311 2.3 25.7 1.0 SG A:CYS292 2.4 22.6 1.0 SG A:CYS308 2.4 20.8 1.0 CB A:CYS318 3.2 26.2 1.0 ZN A:ZN402 3.2 21.2 1.0 CB A:CYS311 3.2 29.1 1.0 CB A:CYS292 3.3 26.9 1.0 CB A:CYS308 3.5 19.5 1.0 CA A:CYS318 3.7 24.9 1.0 N A:CYS308 3.9 20.8 1.0 CA A:CYS308 4.2 19.0 1.0 N A:CYS311 4.3 22.1 1.0 O A:HOH577 4.3 28.9 1.0 CA A:CYS311 4.4 21.9 1.0 C A:CYS318 4.6 26.5 1.0 O A:CYS308 4.7 22.9 1.0 CA A:CYS292 4.7 20.4 1.0 N A:ILE319 4.7 26.0 1.0 C A:CYS308 4.8 18.4 1.0 SG A:CYS302 4.8 20.2 1.0 N A:CYS318 4.8 30.6 1.0 SG A:CYS295 4.8 22.3 1.0 CB A:LYS294 4.9 25.4 1.0 C A:PRO307 5.0 27.5 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of PHO7-Dna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of PHO7-Dna Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn402 b:21.2 occ:1.00 SG A:CYS295 2.3 22.3 1.0 SG A:CYS308 2.4 20.8 1.0 SG A:CYS302 2.4 20.2 1.0 SG A:CYS292 2.4 22.6 1.0 ZN A:ZN401 3.2 24.2 1.0 CB A:CYS295 3.2 18.5 1.0 CB A:CYS308 3.2 19.5 1.0 CB A:CYS302 3.2 17.5 1.0 CB A:CYS292 3.6 26.9 1.0 CA A:CYS302 3.7 15.7 1.0 N A:CYS292 3.9 21.9 1.0 N A:CYS295 4.2 20.6 1.0 CA A:CYS292 4.3 20.4 1.0 CA A:CYS295 4.3 20.4 1.0 O A:HOH534 4.5 25.9 1.0 N A:CYS302 4.6 18.9 1.0 CA A:CYS308 4.7 19.0 1.0 N A:ASP303 4.7 18.9 1.0 SG A:CYS318 4.7 24.9 1.0 C A:CYS302 4.8 17.4 1.0 SG A:CYS311 4.8 25.7 1.0 O A:CYS292 4.8 22.0 1.0 NH1 A:ARG306 4.8 21.5 1.0 C A:CYS292 4.8 20.6 1.0 CB A:ARG310 4.9 25.1 1.0 C A:ALA291 5.0 28.0 1.0

A.Garg, Y.Goldgur, B.Schwer, S.Shuman. Distinctive Structural Basis For Dna Recognition By the Fission Yeast ZN2CYS6 Transcription Factor PHO7 and Its Role in Phosphate Homeostasis. Nucleic Acids Res. V. 46 11262 2018.
ISSN: ESSN 1362-4962
PubMed: 30212894
DOI: 10.1093/NAR/GKY827