Atomistry » Zinc » PDB 6d1a-6dbv » 6d2n
Atomistry »
  Zinc »
    PDB 6d1a-6dbv »
      6d2n »

Zinc in PDB 6d2n: Beta Carbonic Anhydrase in Complex with A Sulfonamide Anion

Enzymatic activity of Beta Carbonic Anhydrase in Complex with A Sulfonamide Anion

All present enzymatic activity of Beta Carbonic Anhydrase in Complex with A Sulfonamide Anion:
4.2.1.1;

Protein crystallography data

The structure of Beta Carbonic Anhydrase in Complex with A Sulfonamide Anion, PDB code: 6d2n was solved by A.Murray, M.Aggarwal, M.Pinard, R.Mckenna, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.70 / 1.90
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 71.374, 77.504, 86.827, 90.00, 90.00, 90.00
R / Rfree (%) 19.8 / 23.7

Zinc Binding Sites:

The binding sites of Zinc atom in the Beta Carbonic Anhydrase in Complex with A Sulfonamide Anion (pdb code 6d2n). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Beta Carbonic Anhydrase in Complex with A Sulfonamide Anion, PDB code: 6d2n:

Zinc binding site 1 out of 1 in 6d2n

Go back to Zinc Binding Sites List in 6d2n
Zinc binding site 1 out of 1 in the Beta Carbonic Anhydrase in Complex with A Sulfonamide Anion


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Beta Carbonic Anhydrase in Complex with A Sulfonamide Anion within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn301

b:34.4
occ:1.00
NAB A:FUS302 2.0 28.2 0.8
NE2 A:HIS98 2.2 33.0 1.0
SG A:CYS42 2.3 28.0 1.0
SG A:CYS101 2.4 30.6 1.0
CE1 A:HIS98 2.9 29.7 1.0
OAD A:FUS302 3.1 47.4 0.8
SAE A:FUS302 3.1 43.9 0.8
CB A:CYS42 3.2 25.1 1.0
CD2 A:HIS98 3.2 39.6 1.0
CB A:CYS101 3.4 28.1 1.0
CA A:CYS101 3.7 30.3 1.0
CB A:ASP44 3.8 33.9 1.0
OAC A:FUS302 3.9 39.1 0.8
ND1 A:HIS98 4.1 38.1 1.0
N A:GLY102 4.1 27.6 1.0
OD1 A:ASP44 4.1 37.1 1.0
CG A:HIS98 4.2 42.5 1.0
C A:CYS101 4.3 37.2 1.0
O A:HOH405 4.3 30.7 1.0
N A:ALA67 4.5 22.6 1.0
NAA A:FUS302 4.5 68.3 0.8
CA A:ALA67 4.5 24.4 1.0
CG A:ASP44 4.5 40.8 1.0
CA A:CYS42 4.7 26.6 1.0
N A:GLY103 4.7 31.0 1.0
N A:ASP44 4.8 22.7 1.0
N A:CYS101 4.9 31.0 1.0
CA A:ASP44 4.9 27.4 1.0

Reference:

A.B.Murray, M.Aggarwal, M.Pinard, D.Vullo, M.Patrauchan, C.T.Supuran, R.Mckenna. Structural Mapping of Anion Inhibitors to Beta-Carbonic Anhydrase PSCA3 From Pseudomonas Aeruginosa. Chemmedchem V. 13 2024 2018.
ISSN: ESSN 1860-7187
PubMed: 30088334
DOI: 10.1002/CMDC.201800375
Page generated: Wed Dec 16 11:39:00 2020

Last articles

Zn in 7M6U
Zn in 7NNG
Zn in 7NEE
Zn in 7NEU
Zn in 7M3K
Zn in 7KWD
Zn in 7KYH
Zn in 7KNG
Zn in 7KY2
Zn in 7KYF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy