Zinc in PDB 6bsf: Human Gr (418-507) in Complex with Monomeric Dna Binding Site

The structure of Human Gr (418-507) in Complex with Monomeric Dna Binding Site, PDB code: 6bsf was solved by M.A.Pufall, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.53 / 2.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	38.345, 87.907, 103.702, 90.00, 90.00, 90.00
R / Rfree (%)	20.6 / 23.3

The binding sites of Zinc atom in the Human Gr (418-507) in Complex with Monomeric Dna Binding Site (pdb code 6bsf). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Human Gr (418-507) in Complex with Monomeric Dna Binding Site, PDB code: 6bsf:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Human Gr (418-507) in Complex with Monomeric Dna Binding Site


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human Gr (418-507) in Complex with Monomeric Dna Binding Site within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn601 b:61.2 occ:1.00 SG B:CYS441 2.2 62.7 1.0 SG B:CYS424 2.3 68.8 1.0 SG B:CYS421 2.4 69.4 1.0 SG B:CYS438 2.4 66.2 1.0 HB3 B:CYS424 2.9 52.0 1.0 HB2 B:CYS441 3.0 62.0 1.0 H B:CYS438 3.1 56.0 1.0 CB B:CYS424 3.2 63.7 1.0 HB3 B:CYS438 3.2 70.0 1.0 H B:CYS424 3.2 61.1 1.0 CB B:CYS441 3.2 63.8 1.0 HB3 B:CYS421 3.4 74.0 1.0 CB B:CYS438 3.4 71.1 1.0 CB B:CYS421 3.5 73.8 1.0 HB2 B:CYS421 3.5 74.0 1.0 HB B:VAL423 3.5 63.0 1.0 H B:CYS441 3.7 50.0 1.0 N B:CYS424 3.7 66.6 1.0 HH21 B:ARG477 3.8 51.2 1.0 HB3 B:ASP426 3.8 72.6 1.0 HH11 B:ARG470 3.9 73.4 1.0 HG B:SER440 3.9 59.3 1.0 HB3 B:CYS441 3.9 62.0 1.0 N B:CYS438 3.9 72.1 1.0 HB2 B:CYS424 4.0 52.0 1.0 CA B:CYS424 4.0 65.1 1.0 HB2 B:CYS438 4.2 70.0 1.0 N B:CYS441 4.2 61.1 1.0 HB B:THR437 4.2 78.9 1.0 CA B:CYS438 4.2 72.4 1.0 H B:ASP426 4.3 68.1 1.0 CA B:CYS441 4.3 59.9 1.0 HD2 B:ARG470 4.3 59.5 1.0 NH1 B:ARG470 4.4 71.8 1.0 HB2 B:ASP426 4.4 72.6 1.0 H B:VAL423 4.5 70.3 1.0 H B:SER425 4.5 59.5 1.0 OG B:SER440 4.5 65.8 1.0 CB B:VAL423 4.5 66.7 1.0 HH12 B:ARG470 4.5 73.4 1.0 CB B:ASP426 4.5 75.0 1.0 NH2 B:ARG477 4.6 57.3 1.0 HA B:CYS441 4.6 53.6 1.0 C B:CYS424 4.7 68.0 1.0 C B:VAL423 4.7 64.6 1.0 HA B:CYS424 4.8 61.5 1.0 N B:SER425 4.8 74.4 1.0 C B:CYS438 4.8 69.6 1.0 HA B:THR437 4.8 79.2 1.0 HG12 B:VAL423 4.8 89.5 1.0 HE B:ARG477 4.8 49.2 1.0 O B:CYS438 4.9 66.3 1.0 N B:ASP426 4.9 77.2 1.0 HD3 B:ARG470 4.9 59.5 1.0 CA B:CYS421 4.9 75.3 1.0 HH22 B:ARG477 4.9 51.2 1.0 CA B:VAL423 5.0 68.6 1.0

Zinc binding site 2 out of 4 in the Human Gr (418-507) in Complex with Monomeric Dna Binding Site


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Human Gr (418-507) in Complex with Monomeric Dna Binding Site within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn602 b:51.7 occ:1.00 SG B:CYS463 2.3 51.0 1.0 SG B:CYS457 2.3 52.7 1.0 SG B:CYS473 2.4 51.5 1.0 SG B:CYS476 2.4 56.3 1.0 HB2 B:CYS476 2.9 36.3 1.0 HB2 B:CYS457 2.9 29.0 1.0 HB2 B:CYS463 3.0 47.5 1.0 CB B:CYS457 3.2 51.8 1.0 H B:CYS463 3.2 37.3 1.0 CB B:CYS476 3.3 50.6 1.0 CB B:CYS463 3.3 51.3 1.0 CB B:CYS473 3.4 49.8 1.0 HB3 B:CYS473 3.5 31.2 1.0 HB2 B:CYS473 3.5 31.2 1.0 H B:ASP462 3.6 44.1 1.0 O B:HOH703 3.6 49.3 1.0 HA B:CYS457 3.7 44.6 1.0 HA B:ASN461 3.8 56.5 1.0 H B:CYS476 3.8 45.0 1.0 HB3 B:CYS476 3.8 36.3 1.0 N B:CYS463 3.9 49.2 1.0 HB3 B:CYS457 4.0 29.0 1.0 HB3 B:CYS463 4.0 47.5 1.0 H B:ALA458 4.0 42.0 1.0 CA B:CYS457 4.0 53.6 1.0 H B:GLY459 4.0 64.2 1.0 O B:HOH702 4.1 53.0 1.0 CA B:CYS463 4.2 52.0 1.0 N B:ASP462 4.3 52.5 1.0 N B:CYS476 4.3 52.1 1.0 HB3 B:ALA475 4.4 42.2 1.0 CA B:CYS476 4.4 52.4 1.0 CA B:ASN461 4.5 53.8 1.0 H B:ARG460 4.5 43.9 1.0 N B:ASN461 4.6 53.9 1.0 N B:ALA458 4.6 54.4 1.0 HA B:CYS463 4.6 44.1 1.0 O B:HOH704 4.7 50.5 1.0 HA B:CYS476 4.7 50.9 1.0 C B:CYS457 4.8 53.8 1.0 C B:ASN461 4.8 52.0 1.0 CA B:CYS473 4.8 50.0 1.0 N B:GLY459 4.8 55.6 1.0 HA3 B:GLY459 5.0 56.2 1.0 HA B:CYS473 5.0 41.5 1.0

Zinc binding site 3 out of 4 in the Human Gr (418-507) in Complex with Monomeric Dna Binding Site


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Human Gr (418-507) in Complex with Monomeric Dna Binding Site within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn601 b:47.6 occ:1.00 SG A:CYS463 2.3 49.1 1.0 SG A:CYS457 2.3 53.3 1.0 SG A:CYS473 2.4 44.6 1.0 SG A:CYS476 2.5 55.1 1.0 HB2 A:CYS463 3.0 67.6 1.0 HB2 A:CYS476 3.1 36.6 1.0 HB2 A:CYS457 3.1 54.3 1.0 CB A:CYS457 3.3 51.9 1.0 H A:CYS463 3.3 37.0 1.0 CB A:CYS463 3.3 52.7 1.0 CB A:CYS473 3.4 52.9 1.0 HB2 A:CYS473 3.4 38.8 1.0 CB A:CYS476 3.4 52.3 1.0 HA A:CYS457 3.5 69.8 1.0 HB3 A:CYS473 3.5 38.8 1.0 H A:CYS476 3.6 55.5 1.0 HA A:ASN461 3.6 44.0 1.0 O A:HOH705 3.7 49.9 1.0 H A:GLY459 3.8 72.8 1.0 H A:ASN461 3.9 90.1 0.5 H A:ASN461 3.9 90.1 0.5 CA A:CYS457 3.9 51.7 1.0 HB3 A:CYS463 4.0 67.6 1.0 N A:CYS463 4.0 50.5 1.0 HB3 A:CYS476 4.1 36.6 1.0 HB3 A:CYS457 4.1 54.3 1.0 H A:ALA458 4.2 45.2 1.0 N A:CYS476 4.2 50.6 1.0 HB3 A:ALA475 4.2 32.9 1.0 CA A:CYS463 4.3 52.4 1.0 CA A:ASN461 4.3 50.7 1.0 CA A:CYS476 4.4 49.6 1.0 H A:ASP462 4.4 61.2 1.0 N A:ASN461 4.4 55.1 1.0 O A:HOH704 4.6 53.3 1.0 N A:ALA458 4.6 47.6 1.0 N A:GLY459 4.6 52.0 1.0 N A:ASP462 4.6 52.8 1.0 C A:CYS457 4.7 50.9 1.0 HA3 A:GLY459 4.7 37.2 1.0 HA A:CYS476 4.7 38.5 1.0 C A:ASN461 4.7 53.6 1.0 HA A:CYS463 4.8 38.2 1.0 CA A:CYS473 4.8 54.6 1.0 HH21 A:ARG479 4.9 92.0 1.0 HA A:CYS473 4.9 59.5 1.0 HD11 A:ILE465 5.0 0.8 1.0

Zinc binding site 4 out of 4 in the Human Gr (418-507) in Complex with Monomeric Dna Binding Site


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Human Gr (418-507) in Complex with Monomeric Dna Binding Site within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn602 b:57.3 occ:1.00 SG A:CYS438 2.2 62.7 1.0 SG A:CYS424 2.3 66.7 1.0 SG A:CYS441 2.3 57.9 1.0 SG A:CYS421 2.5 69.5 1.0 HB2 A:CYS441 2.9 63.9 1.0 H A:CYS424 2.9 43.9 1.0 H A:CYS438 3.0 53.7 1.0 HB3 A:CYS424 3.1 66.7 1.0 HB3 A:CYS421 3.2 83.4 1.0 CB A:CYS441 3.2 56.5 1.0 CB A:CYS421 3.3 68.0 1.0 CB A:CYS424 3.3 63.8 1.0 HB2 A:CYS421 3.3 83.4 1.0 HB3 A:CYS438 3.4 79.2 1.0 CB A:CYS438 3.4 67.6 1.0 HB A:VAL423 3.6 45.1 1.0 N A:CYS424 3.6 58.9 1.0 H A:CYS441 3.7 55.5 1.0 HH11 A:ARG470 3.7 64.6 1.0 N A:CYS438 3.8 64.8 1.0 HB3 A:CYS441 3.8 63.9 1.0 HH21 A:ARG477 3.8 54.5 1.0 H A:ASP426 3.9 53.3 1.0 HB2 A:ASP426 3.9 90.0 1.0 CA A:CYS424 4.0 63.2 1.0 HB2 A:CYS424 4.1 66.7 1.0 CA A:CYS438 4.1 64.8 1.0 HB3 A:ASP426 4.2 90.0 1.0 HB2 A:CYS438 4.2 79.2 1.0 N A:CYS441 4.2 66.8 1.0 HD2 A:ARG470 4.2 58.9 1.0 H A:SER425 4.3 79.5 1.0 CA A:CYS441 4.3 62.1 1.0 NH1 A:ARG470 4.4 63.5 1.0 HB A:THR437 4.4 61.1 1.0 H A:VAL423 4.4 49.2 1.0 CB A:ASP426 4.5 77.4 1.0 HB3 A:SER440 4.5 66.0 1.0 CB A:VAL423 4.5 57.0 1.0 HA A:THR437 4.5 41.2 1.0 HH12 A:ARG470 4.6 64.6 1.0 N A:SER425 4.6 73.2 1.0 C A:CYS424 4.7 66.5 1.0 C A:VAL423 4.7 62.1 1.0 N A:ASP426 4.7 74.7 1.0 NH2 A:ARG477 4.7 44.7 1.0 HA A:CYS441 4.7 57.6 1.0 HE A:ARG477 4.7 48.8 1.0 HG12 A:VAL423 4.7 52.2 1.0 HD3 A:ARG470 4.7 58.9 1.0 CA A:CYS421 4.7 65.8 1.0 C A:CYS438 4.8 62.3 1.0 HA A:CYS424 4.8 67.3 1.0 O A:CYS438 4.8 58.8 1.0 C A:THR437 4.9 68.6 1.0 CD A:ARG470 4.9 64.2 1.0 CA A:VAL423 5.0 60.2 1.0 HA A:CYS438 5.0 53.1 1.0

M.A.Pufall, M.A.Pufall. N/A N/A.