Atomistry » Zinc » PDB 6bml-6bvd » 6bse
Atomistry »
  Zinc »
    PDB 6bml-6bvd »
      6bse »

Zinc in PDB 6bse: Glucocorticoid Receptor Bound to High Cooperativity Monomer Sequence

Protein crystallography data

The structure of Glucocorticoid Receptor Bound to High Cooperativity Monomer Sequence, PDB code: 6bse was solved by M.A.Pufall, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 16.75 / 2.35
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 39.447, 95.172, 104.719, 90.00, 90.00, 90.00
R / Rfree (%) 19.2 / 22.9

Zinc Binding Sites:

The binding sites of Zinc atom in the Glucocorticoid Receptor Bound to High Cooperativity Monomer Sequence (pdb code 6bse). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Glucocorticoid Receptor Bound to High Cooperativity Monomer Sequence, PDB code: 6bse:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in 6bse

Go back to Zinc Binding Sites List in 6bse
Zinc binding site 1 out of 4 in the Glucocorticoid Receptor Bound to High Cooperativity Monomer Sequence


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Glucocorticoid Receptor Bound to High Cooperativity Monomer Sequence within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn601

b:34.3
occ:1.00
SG A:CYS424 2.2 29.8 1.0
SG A:CYS438 2.3 35.6 1.0
SG A:CYS421 2.4 29.0 1.0
SG A:CYS441 2.4 35.8 1.0
HB3 A:CYS424 3.1 29.4 1.0
HB2 A:CYS441 3.1 34.6 1.0
H A:CYS438 3.2 44.8 1.0
CB A:CYS424 3.3 24.5 1.0
HB3 A:CYS421 3.3 44.9 1.0
H A:CYS424 3.3 37.4 1.0
CB A:CYS421 3.3 37.4 1.0
HB2 A:CYS421 3.4 44.9 1.0
HB3 A:CYS438 3.4 51.0 1.0
CB A:CYS441 3.4 28.8 1.0
CB A:CYS438 3.5 42.5 1.0
HB A:VAL423 3.7 29.5 1.0
H A:CYS441 3.7 35.3 1.0
HH11 A:ARG470 3.7 62.1 1.0
N A:CYS424 3.8 31.2 1.0
HG A:SER440 3.8 52.6 1.0
HB3 A:ASP426 3.8 48.9 1.0
HH21 A:ARG477 4.0 44.3 1.0
N A:CYS438 4.0 37.4 1.0
HB2 A:CYS424 4.0 29.4 1.0
HB3 A:CYS441 4.0 34.6 1.0
CA A:CYS424 4.0 32.1 1.0
HB2 A:ASP426 4.2 48.9 1.0
OG A:SER440 4.2 43.8 1.0
H A:ASP426 4.2 49.0 1.0
HB2 A:CYS438 4.3 51.0 1.0
N A:CYS441 4.3 29.4 1.0
NH1 A:ARG470 4.3 51.7 1.0
HH12 A:ARG470 4.3 62.1 1.0
CA A:CYS438 4.3 36.2 1.0
H A:VAL423 4.4 33.5 1.0
CA A:CYS441 4.4 28.7 1.0
CB A:ASP426 4.4 40.7 1.0
HB A:THR437 4.5 33.9 1.0
HG12 A:VAL423 4.5 39.5 1.0
CB A:VAL423 4.6 24.6 1.0
C A:CYS424 4.6 23.4 1.0
H A:SER425 4.6 28.8 1.0
HD2 A:ARG470 4.7 43.3 1.0
C A:VAL423 4.7 32.3 1.0
HA A:THR437 4.7 33.7 1.0
NH2 A:ARG477 4.7 36.9 1.0
CA A:CYS421 4.8 36.2 1.0
N A:SER425 4.8 24.0 1.0
HA A:CYS441 4.8 34.4 1.0
N A:ASP426 4.9 40.9 1.0
HA A:CYS424 4.9 38.5 1.0
HD3 A:ARG470 4.9 43.3 1.0
O A:CYS438 5.0 31.6 1.0
CG1 A:VAL423 5.0 32.9 1.0
HE A:ARG477 5.0 31.8 1.0
C A:CYS438 5.0 41.2 1.0

Zinc binding site 2 out of 4 in 6bse

Go back to Zinc Binding Sites List in 6bse
Zinc binding site 2 out of 4 in the Glucocorticoid Receptor Bound to High Cooperativity Monomer Sequence


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Glucocorticoid Receptor Bound to High Cooperativity Monomer Sequence within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn602

b:28.6
occ:1.00
SG A:CYS473 2.2 28.9 1.0
SG A:CYS457 2.2 39.5 1.0
SG A:CYS463 2.3 26.6 1.0
SG A:CYS476 2.5 30.8 1.0
HB2 A:CYS463 3.0 28.3 1.0
HB2 A:CYS476 3.0 33.0 1.0
HB2 A:CYS457 3.0 42.1 1.0
CB A:CYS457 3.2 35.1 1.0
H A:CYS463 3.2 29.5 1.0
CB A:CYS463 3.2 23.6 1.0
CB A:CYS473 3.3 24.9 1.0
CB A:CYS476 3.4 27.5 1.0
HB3 A:CYS473 3.4 29.9 1.0
HB2 A:CYS473 3.4 29.9 1.0
HA A:ASN461 3.5 34.9 1.0
HA A:CYS457 3.6 34.4 1.0
H A:CYS476 3.7 36.2 1.0
H A:ASN461 3.8 33.9 1.0
O A:HOH731 3.8 26.4 1.0
HB3 A:CYS463 3.9 28.3 1.0
N A:CYS463 4.0 24.6 1.0
CA A:CYS457 4.0 28.7 1.0
H A:GLY459 4.0 42.6 1.0
HB3 A:CYS457 4.0 42.1 1.0
HB3 A:CYS476 4.0 33.0 1.0
H A:ALA458 4.2 37.7 1.0
CA A:CYS463 4.2 24.0 1.0
H A:ASP462 4.2 38.9 1.0
CA A:ASN461 4.3 29.1 1.0
N A:CYS476 4.3 30.1 1.0
N A:ASN461 4.4 28.2 1.0
CA A:CYS476 4.4 32.0 1.0
HB3 A:ALA475 4.5 30.4 1.0
O A:HOH718 4.5 31.8 1.0
N A:ASP462 4.5 32.4 1.0
HH21 A:ARG479 4.6 44.7 1.0
HA3 A:GLY459 4.6 33.8 1.0
HA A:CYS476 4.6 38.5 1.0
C A:ASN461 4.7 41.1 1.0
N A:ALA458 4.7 31.4 1.0
CA A:CYS473 4.7 29.6 1.0
O A:HOH730 4.7 33.5 1.0
HA A:CYS463 4.7 28.8 1.0
C A:CYS457 4.8 29.5 1.0
N A:GLY459 4.8 35.5 1.0
HA A:CYS473 4.9 35.5 1.0

Zinc binding site 3 out of 4 in 6bse

Go back to Zinc Binding Sites List in 6bse
Zinc binding site 3 out of 4 in the Glucocorticoid Receptor Bound to High Cooperativity Monomer Sequence


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Glucocorticoid Receptor Bound to High Cooperativity Monomer Sequence within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn601

b:42.9
occ:1.00
SG B:CYS441 2.2 43.3 1.0
SG B:CYS424 2.3 44.9 1.0
SG B:CYS438 2.3 42.1 1.0
SG B:CYS421 2.3 46.3 1.0
HB2 B:CYS441 2.9 40.2 1.0
HB3 B:CYS424 3.1 37.4 1.0
H B:CYS438 3.1 47.4 1.0
HB3 B:CYS421 3.1 53.1 1.0
CB B:CYS441 3.2 33.5 1.0
H B:CYS424 3.2 59.7 1.0
CB B:CYS421 3.2 44.2 1.0
CB B:CYS424 3.3 31.2 1.0
HB2 B:CYS421 3.3 53.1 1.0
HH11 B:ARG470 3.5 45.3 1.0
HB3 B:CYS438 3.6 58.2 1.0
CB B:CYS438 3.6 48.5 1.0
H B:CYS441 3.7 40.8 1.0
HB B:VAL423 3.7 54.7 1.0
N B:CYS424 3.7 49.7 1.0
HB3 B:ASP426 3.8 65.1 1.0
HB3 B:CYS441 3.8 40.2 1.0
N B:CYS438 3.9 39.5 1.0
HG B:SER440 4.0 52.9 1.0
HH21 B:ARG477 4.0 52.5 1.0
CA B:CYS424 4.1 39.2 1.0
HB2 B:CYS424 4.1 37.4 1.0
NH1 B:ARG470 4.1 37.7 1.0
HH12 B:ARG470 4.2 45.3 1.0
N B:CYS441 4.3 34.0 1.0
HB2 B:ASP426 4.3 65.1 1.0
CA B:CYS438 4.3 40.0 1.0
CA B:CYS441 4.3 33.4 1.0
HB2 B:CYS438 4.3 58.2 1.0
HB B:THR437 4.4 58.0 1.0
H B:ASP426 4.4 59.5 1.0
H B:SER425 4.4 58.2 1.0
H B:VAL423 4.4 62.9 1.0
CB B:ASP426 4.5 54.3 1.0
HD2 B:ARG470 4.5 53.8 1.0
OG B:SER440 4.5 44.1 1.0
HG12 B:VAL423 4.6 40.1 1.0
CB B:VAL423 4.6 45.6 1.0
HA B:THR437 4.7 48.9 1.0
CA B:CYS421 4.7 60.6 1.0
C B:VAL423 4.7 44.5 1.0
HA B:CYS441 4.7 40.1 1.0
C B:CYS424 4.7 43.2 1.0
N B:SER425 4.8 48.5 1.0
NH2 B:ARG477 4.8 43.8 1.0
HD3 B:ARG470 4.9 53.8 1.0
HA B:CYS424 4.9 47.0 1.0
HE B:ARG477 4.9 48.8 1.0
C B:CYS438 5.0 39.0 1.0
N B:ASP426 5.0 49.6 1.0
CG1 B:VAL423 5.0 33.4 1.0
CA B:VAL423 5.0 42.5 1.0

Zinc binding site 4 out of 4 in 6bse

Go back to Zinc Binding Sites List in 6bse
Zinc binding site 4 out of 4 in the Glucocorticoid Receptor Bound to High Cooperativity Monomer Sequence


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Glucocorticoid Receptor Bound to High Cooperativity Monomer Sequence within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn602

b:28.6
occ:1.00
SG B:CYS473 2.2 28.9 1.0
SG B:CYS463 2.3 29.0 1.0
SG B:CYS476 2.3 33.4 1.0
SG B:CYS457 2.3 29.2 1.0
HB2 B:CYS463 2.9 35.6 1.0
HB2 B:CYS457 3.0 31.8 1.0
HB2 B:CYS476 3.1 31.6 1.0
CB B:CYS463 3.2 29.7 1.0
CB B:CYS457 3.2 26.5 1.0
H B:CYS463 3.3 31.3 1.0
CB B:CYS473 3.4 34.2 1.0
CB B:CYS476 3.4 26.3 1.0
HB3 B:CYS473 3.4 41.0 1.0
HB2 B:CYS473 3.4 41.0 1.0
HA B:CYS457 3.6 32.6 1.0
O B:HOH709 3.7 27.8 1.0
HA B:ASN461 3.7 39.1 1.0
H B:CYS476 3.8 43.5 1.0
N B:CYS463 3.9 26.1 1.0
HB3 B:CYS463 3.9 35.6 1.0
CA B:CYS457 4.0 27.2 1.0
HB3 B:CYS476 4.0 31.6 1.0
H B:ASN461 4.0 30.5 1.0
HB3 B:CYS457 4.0 31.8 1.0
H B:GLY459 4.0 34.9 1.0
H B:ASP462 4.1 30.1 1.0
CA B:CYS463 4.2 23.1 1.0
HB3 B:ALA475 4.3 41.2 1.0
O B:HOH713 4.3 27.1 1.0
N B:CYS476 4.3 36.2 1.0
H B:ALA458 4.3 32.0 1.0
CA B:ASN461 4.4 32.6 1.0
HH21 B:ARG479 4.4 0.2 1.0
CA B:CYS476 4.5 28.3 1.0
N B:ASP462 4.5 25.0 1.0
N B:ASN461 4.5 25.4 1.0
H B:ARG460 4.5 33.4 1.0
HA B:CYS463 4.6 27.7 1.0
N B:ALA458 4.7 26.7 1.0
C B:ASN461 4.8 34.7 1.0
CA B:CYS473 4.8 30.0 1.0
C B:CYS457 4.8 45.6 1.0
HA B:CYS476 4.8 33.9 1.0
N B:GLY459 4.9 29.1 1.0
HA B:CYS473 4.9 36.0 1.0
C B:ASP462 5.0 33.0 1.0

Reference:

M.A.Pufall, L.Zhang. General and Sequence-Specific Roles For Dna in Glucocorticoid Receptor Dna-Binding Stoichiometry To Be Published.
Page generated: Wed Dec 16 11:33:07 2020

Last articles

Zn in 7NN0
Zn in 7NIO
Zn in 7LUP
Zn in 7M1Y
Zn in 7LO4
Zn in 7KWO
Zn in 7KJY
Zn in 7KCQ
Zn in 7KC2
Zn in 7KCB
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy