Zinc in PDB 5yle: Mcr-1 Complex with Ethanolamine (Eta)

The structure of Mcr-1 Complex with Ethanolamine (Eta), PDB code: 5yle was solved by P.C.Wei, G.J.Song, M.Y.Shi, Y.F.Zhou, Y.Liu, J.Lei, P.Chen, L.Yin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.69 / 1.85
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	51.860, 73.270, 82.810, 90.00, 90.00, 90.00
R / Rfree (%)	15.9 / 20.5

The binding sites of Zinc atom in the Mcr-1 Complex with Ethanolamine (Eta) (pdb code 5yle). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Mcr-1 Complex with Ethanolamine (Eta), PDB code: 5yle:

Zinc binding site 1 out of 1 in the Mcr-1 Complex with Ethanolamine (Eta)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Mcr-1 Complex with Ethanolamine (Eta) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn402 b:10.5 occ:0.78 OE1 A:GLU31 2.1 9.4 1.0 NE2 A:HIS251 2.1 9.2 1.0 OD2 A:ASP250 2.1 10.5 1.0 OE2 A:GLU31 2.1 14.8 1.0 OG1 A:TPO70 2.2 9.6 1.0 CD A:GLU31 2.4 9.3 1.0 O1P A:TPO70 2.5 11.4 1.0 CE1 A:HIS251 2.9 9.3 1.0 P A:TPO70 2.9 12.0 1.0 CG A:ASP250 3.0 12.0 1.0 CD2 A:HIS251 3.1 9.5 1.0 OD1 A:ASP250 3.3 7.2 1.0 CB A:TPO70 3.4 10.0 1.0 O2P A:TPO70 3.7 10.5 1.0 CA A:TPO70 3.8 12.4 1.0 N A:TPO70 3.8 11.9 1.0 CG A:GLU31 3.9 9.8 1.0 O A:HOH527 3.9 25.9 1.0 ND1 A:HIS251 4.0 9.2 1.0 CG2 A:TPO70 4.0 7.9 1.0 O A:HOH535 4.1 15.6 1.0 CG A:HIS251 4.1 9.8 1.0 OG1 A:THR32 4.2 11.8 1.0 NE2 A:HIS263 4.2 12.5 1.0 O3P A:TPO70 4.2 12.7 1.0 CB A:ASP250 4.4 10.1 1.0 C A:SER69 4.5 12.3 1.0 CA A:GLU31 4.6 8.2 1.0 N A:THR32 4.6 8.0 1.0 CB A:GLU31 4.6 8.9 1.0 CB A:ETA401 4.7 22.7 1.0 CE1 A:HIS263 4.8 12.0 1.0 CD2 A:HIS263 4.9 10.5 1.0 ND2 A:ASN114 4.9 10.7 1.0

P.Wei, G.Song, M.Shi, Y.Zhou, Y.Liu, J.Lei, P.Chen, L.Yin. Substrate Analog Interaction with Mcr-1 Offers Insight Into the Rising Threat of the Plasmid-Mediated Transferable Colistin Resistance. Faseb J. V. 32 1085 2018.
ISSN: ESSN 1530-6860
PubMed: 29079699
DOI: 10.1096/FJ.201700705R