Zinc in PDB 5y5b: Crystal Structure of Imp-1 Metallo-Beta-Lactamase

All present enzymatic activity of Crystal Structure of Imp-1 Metallo-Beta-Lactamase:
3.5.2.6;

The structure of Crystal Structure of Imp-1 Metallo-Beta-Lactamase, PDB code: 5y5b was solved by J.Wachino, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.53 / 1.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	36.010, 57.730, 101.060, 90.00, 90.00, 90.00
R / Rfree (%)	15.5 / 19.9

The binding sites of Zinc atom in the Crystal Structure of Imp-1 Metallo-Beta-Lactamase (pdb code 5y5b). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Imp-1 Metallo-Beta-Lactamase, PDB code: 5y5b:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Imp-1 Metallo-Beta-Lactamase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Imp-1 Metallo-Beta-Lactamase within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:9.1 occ:1.00 O A:HOH551 1.9 10.8 1.0 NE2 A:HIS139 2.0 7.6 1.0 NE2 A:HIS77 2.0 8.3 1.0 ND1 A:HIS79 2.0 8.9 1.0 CD2 A:HIS77 3.0 7.9 1.0 CE1 A:HIS79 3.0 9.4 1.0 CE1 A:HIS139 3.0 7.6 1.0 CD2 A:HIS139 3.0 7.6 1.0 CG A:HIS79 3.1 9.4 1.0 CE1 A:HIS77 3.1 9.4 1.0 CB A:HIS79 3.4 8.6 1.0 ZN A:ZN302 3.4 15.4 1.0 O A:HOH409 3.5 24.2 1.0 SG A:CYS158 3.7 10.7 1.0 OD1 A:ASP81 3.8 14.5 1.0 CB A:CYS158 3.8 10.3 1.0 O3 A:SO4303 3.9 14.9 1.0 NE2 A:HIS79 4.1 10.6 1.0 ND1 A:HIS139 4.1 7.5 1.0 CG A:HIS77 4.2 7.7 1.0 ND1 A:HIS77 4.2 8.4 1.0 CG A:HIS139 4.2 8.1 1.0 CD2 A:HIS79 4.2 10.6 1.0 OD2 A:ASP81 4.4 11.7 1.0 CG A:ASP81 4.5 12.4 1.0 CG2 A:THR140 4.7 7.8 1.0 O A:HOH425 4.7 21.9 1.0 CA A:HIS79 4.8 8.3 1.0 S A:SO4303 4.8 20.9 1.0 O4 A:SO4303 4.9 23.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Imp-1 Metallo-Beta-Lactamase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Imp-1 Metallo-Beta-Lactamase within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:15.4 occ:1.00 OD2 A:ASP81 2.1 11.7 1.0 O A:HOH551 2.1 10.8 1.0 NE2 A:HIS197 2.1 10.4 1.0 O3 A:SO4303 2.3 14.9 1.0 SG A:CYS158 2.4 10.7 1.0 O A:HOH425 2.5 21.9 1.0 CD2 A:HIS197 3.1 11.8 1.0 CG A:ASP81 3.1 12.4 1.0 CE1 A:HIS197 3.1 12.6 1.0 ZN A:ZN301 3.4 9.1 1.0 OD1 A:ASP81 3.5 14.5 1.0 S A:SO4303 3.5 20.9 1.0 CB A:CYS158 3.5 10.3 1.0 O4 A:SO4303 3.7 23.2 1.0 O1 A:SO4303 4.1 24.8 1.0 O A:HOH409 4.2 24.2 1.0 O A:HOH461 4.2 35.2 1.0 ND1 A:HIS197 4.2 12.1 1.0 CG A:HIS197 4.2 11.8 1.0 NE2 A:HIS139 4.3 7.6 1.0 NE2 A:HIS77 4.4 8.3 1.0 CB A:ASP81 4.4 9.5 1.0 CE1 A:HIS77 4.4 9.4 1.0 CB A:SER196 4.6 10.1 1.0 O2 A:SO4303 4.7 20.9 1.0 CA A:CYS158 4.7 10.1 1.0 CE1 A:HIS139 4.7 7.6 1.0 OG A:SER196 4.8 9.6 1.0 CD A:LYS33 4.8 10.2 1.0 CE A:LYS33 4.9 9.8 1.0

J.Wachino, J.Wachino. N/A N/A.