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Zinc in PDB 5xze: Mouse Cgas Bound to the Inhibitor RU332Enzymatic activity of Mouse Cgas Bound to the Inhibitor RU332
All present enzymatic activity of Mouse Cgas Bound to the Inhibitor RU332:
2.7.7.86; Protein crystallography data
The structure of Mouse Cgas Bound to the Inhibitor RU332, PDB code: 5xze
was solved by
J.Vincent,
C.Adura,
P.Gao,
A.Luz,
L.Lama,
Y.Asano,
R.Okamoto,
T.Imaeda,
J.Aida,
K.Rothamel,
T.Gogakos,
J.Steinberg,
S.Reasoner,
K.Aso,
T.Tuschl,
D.J.Patel,
J.F.Glickman,
M.Ascano,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Mouse Cgas Bound to the Inhibitor RU332
(pdb code 5xze). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Mouse Cgas Bound to the Inhibitor RU332, PDB code: 5xze: Zinc binding site 1 out of 1 in 5xzeGo back to Zinc Binding Sites List in 5xze
Zinc binding site 1 out
of 1 in the Mouse Cgas Bound to the Inhibitor RU332
Mono view Stereo pair view
Reference:
J.Vincent,
C.Adura,
P.Gao,
A.Luz,
L.Lama,
Y.Asano,
R.Okamoto,
T.Imaeda,
J.Aida,
K.Rothamel,
T.Gogakos,
J.Steinberg,
S.Reasoner,
K.Aso,
T.Tuschl,
D.J.Patel,
J.F.Glickman,
M.Ascano.
Small Molecule Inhibition of Cgas Reduces Interferon Expression in Primary Macrophages From Autoimmune Mice. Nat Commun V. 8 750 2017.
Page generated: Wed Dec 16 11:21:40 2020
ISSN: ESSN 2041-1723 PubMed: 28963528 DOI: 10.1038/S41467-017-00833-9 |
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