Zinc in PDB 5xqz: Structure of the MOB1-NDR2 Complex

All present enzymatic activity of Structure of the MOB1-NDR2 Complex:
2.7.11.1;

The structure of Structure of the MOB1-NDR2 Complex, PDB code: 5xqz was solved by G.Wu, K.Lin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.10
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	57.519, 94.424, 102.200, 90.00, 90.00, 90.00
R / Rfree (%)	15.6 / 24.4

The binding sites of Zinc atom in the Structure of the MOB1-NDR2 Complex (pdb code 5xqz). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of the MOB1-NDR2 Complex, PDB code: 5xqz:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of the MOB1-NDR2 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the MOB1-NDR2 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:41.0 occ:1.00 NE2 A:HIS166 1.9 41.3 1.0 NE2 A:HIS161 2.0 39.2 1.0 SG A:CYS79 2.3 41.3 1.0 SG A:CYS84 2.4 43.2 1.0 CE1 A:HIS166 2.8 44.1 1.0 CD2 A:HIS166 3.0 41.4 1.0 CD2 A:HIS161 3.0 30.8 1.0 CE1 A:HIS161 3.1 40.8 1.0 CB A:CYS79 3.3 46.1 1.0 CB A:CYS84 3.4 44.5 1.0 CA A:CYS79 3.8 47.2 1.0 ND1 A:HIS166 4.0 40.8 1.0 CB A:ALA111 4.0 38.5 1.0 CG A:HIS166 4.1 43.3 1.0 ND1 A:HIS161 4.2 36.6 1.0 CG A:HIS161 4.2 33.5 1.0 OG A:SER83 4.6 48.2 1.0 C A:CYS79 4.7 42.8 1.0 CB A:GLN165 4.7 40.2 1.0 O A:HOH1103 4.8 64.2 1.0 CA A:CYS84 4.9 40.1 1.0 N A:CYS79 4.9 50.5 1.0 N A:THR80 5.0 45.2 1.0

Zinc binding site 2 out of 2 in the Structure of the MOB1-NDR2 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of the MOB1-NDR2 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1001 b:28.8 occ:1.00 NE2 B:HIS166 2.0 25.9 1.0 NE2 B:HIS161 2.1 25.6 1.0 SG B:CYS79 2.3 30.2 1.0 SG B:CYS84 2.3 29.0 1.0 CE1 B:HIS166 2.9 27.3 1.0 CD2 B:HIS166 3.0 27.3 1.0 CE1 B:HIS161 3.0 28.1 1.0 CD2 B:HIS161 3.1 24.3 1.0 CB B:CYS79 3.3 32.4 1.0 CB B:CYS84 3.3 29.2 1.0 CB B:ALA111 3.8 26.4 1.0 CA B:CYS79 3.8 32.1 1.0 ND1 B:HIS166 4.1 29.4 1.0 CG B:HIS166 4.1 27.8 1.0 ND1 B:HIS161 4.2 26.7 1.0 CG B:HIS161 4.2 25.1 1.0 OG B:SER83 4.5 33.1 1.0 C B:CYS79 4.6 33.4 1.0 CB B:GLN165 4.7 33.8 1.0 CA B:CYS84 4.8 30.8 1.0 N B:THR80 4.9 31.3 1.0

Y.Kulaberoglu, K.Lin, M.Holder, Z.Gai, M.Gomez, B.Assefa Shifa, M.Mavis, L.Hoa, A.A.D.Sharif, C.Lujan, E.S.J.Smith, I.Bjedov, N.Tapon, G.Wu, A.Hergovich. Stable MOB1 Interaction with Hippo/Mst Is Not Essential For Development and Tissue Growth Control. Nat Commun V. 8 695 2017.
ISSN: ESSN 2041-1723
PubMed: 28947795
DOI: 10.1038/S41467-017-00795-Y