Zinc in PDB 5we0: Structural Basis For Shelterin Bridge Assembly
Protein crystallography data
The structure of Structural Basis For Shelterin Bridge Assembly, PDB code: 5we0
was solved by
J.-K.Kim,
J.Liu,
X.Hu,
C.Yu,
K.Roskamp,
B.Sankaran,
L.Huang,
E.-A.Komives,
F.Qiao,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
62.71 /
2.30
|
Space group
|
P 1
|
Cell size a, b, c (Å), α, β, γ (°)
|
56.720,
82.010,
103.510,
89.99,
89.98,
73.96
|
R / Rfree (%)
|
19.9 /
22.8
|
Zinc Binding Sites:
The binding sites of Zinc atom in the Structural Basis For Shelterin Bridge Assembly
(pdb code 5we0). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the
Structural Basis For Shelterin Bridge Assembly, PDB code: 5we0:
Jump to Zinc binding site number:
1;
2;
3;
4;
Zinc binding site 1 out
of 4 in 5we0
Go back to
Zinc Binding Sites List in 5we0
Zinc binding site 1 out
of 4 in the Structural Basis For Shelterin Bridge Assembly
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Structural Basis For Shelterin Bridge Assembly within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn601
b:49.1
occ:1.00
|
NE2
|
B:HIS488
|
2.1
|
42.0
|
1.0
|
NE2
|
A:HIS49
|
2.1
|
49.8
|
1.0
|
SG
|
B:CYS482
|
2.4
|
47.8
|
1.0
|
SG
|
B:CYS479
|
2.5
|
47.3
|
1.0
|
CD2
|
B:HIS488
|
2.9
|
42.7
|
1.0
|
CE1
|
A:HIS49
|
3.0
|
49.3
|
1.0
|
CD2
|
A:HIS49
|
3.1
|
42.0
|
1.0
|
CE1
|
B:HIS488
|
3.2
|
42.0
|
1.0
|
CB
|
B:CYS479
|
3.2
|
51.6
|
1.0
|
CB
|
B:CYS482
|
3.4
|
45.5
|
1.0
|
N
|
B:CYS482
|
3.6
|
44.3
|
1.0
|
CA
|
B:CYS482
|
3.9
|
50.7
|
1.0
|
ND1
|
A:HIS49
|
4.1
|
45.8
|
1.0
|
CG
|
B:HIS488
|
4.1
|
40.7
|
1.0
|
CG
|
A:HIS49
|
4.2
|
44.3
|
1.0
|
ND1
|
B:HIS488
|
4.2
|
41.6
|
1.0
|
CB
|
A:CYS48
|
4.3
|
42.1
|
1.0
|
C
|
B:MET481
|
4.5
|
47.1
|
1.0
|
CA
|
B:CYS479
|
4.6
|
55.0
|
1.0
|
CB
|
B:MET481
|
4.7
|
46.3
|
1.0
|
C
|
B:CYS479
|
4.9
|
52.6
|
1.0
|
O
|
B:CYS479
|
4.9
|
52.6
|
1.0
|
|
Zinc binding site 2 out
of 4 in 5we0
Go back to
Zinc Binding Sites List in 5we0
Zinc binding site 2 out
of 4 in the Structural Basis For Shelterin Bridge Assembly
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Structural Basis For Shelterin Bridge Assembly within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn601
b:73.5
occ:1.00
|
NE2
|
E:HIS488
|
2.0
|
59.6
|
1.0
|
NE2
|
D:HIS49
|
2.1
|
64.0
|
1.0
|
SG
|
E:CYS482
|
2.5
|
73.1
|
1.0
|
SG
|
E:CYS479
|
2.6
|
79.8
|
1.0
|
CE1
|
E:HIS488
|
2.6
|
59.0
|
1.0
|
CB
|
E:CYS479
|
2.9
|
81.8
|
1.0
|
CE1
|
D:HIS49
|
2.9
|
64.7
|
1.0
|
CD2
|
E:HIS488
|
3.2
|
52.9
|
1.0
|
CD2
|
D:HIS49
|
3.2
|
58.2
|
1.0
|
CB
|
E:CYS482
|
3.5
|
81.7
|
1.0
|
N
|
E:CYS482
|
3.6
|
80.5
|
1.0
|
ND1
|
E:HIS488
|
3.8
|
56.8
|
1.0
|
CA
|
E:CYS482
|
4.0
|
81.9
|
1.0
|
ND1
|
D:HIS49
|
4.1
|
61.4
|
1.0
|
CG
|
E:HIS488
|
4.1
|
52.8
|
1.0
|
CG
|
D:HIS49
|
4.2
|
57.0
|
1.0
|
CA
|
E:CYS479
|
4.3
|
87.4
|
1.0
|
CB
|
D:CYS48
|
4.4
|
55.3
|
1.0
|
C
|
E:MET481
|
4.5
|
79.6
|
1.0
|
CB
|
E:MET481
|
4.5
|
72.9
|
1.0
|
C
|
E:CYS479
|
4.7
|
87.0
|
1.0
|
CA
|
E:MET481
|
4.9
|
79.0
|
1.0
|
N
|
E:MET481
|
5.0
|
87.8
|
1.0
|
|
Zinc binding site 3 out
of 4 in 5we0
Go back to
Zinc Binding Sites List in 5we0
Zinc binding site 3 out
of 4 in the Structural Basis For Shelterin Bridge Assembly
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Structural Basis For Shelterin Bridge Assembly within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Zn601
b:48.7
occ:1.00
|
NE2
|
G:HIS49
|
2.1
|
49.1
|
1.0
|
NE2
|
H:HIS488
|
2.1
|
43.4
|
1.0
|
SG
|
H:CYS479
|
2.4
|
47.0
|
1.0
|
SG
|
H:CYS482
|
2.4
|
51.2
|
1.0
|
CE1
|
G:HIS49
|
2.8
|
48.3
|
1.0
|
CD2
|
H:HIS488
|
3.0
|
44.0
|
1.0
|
CD2
|
G:HIS49
|
3.1
|
43.7
|
1.0
|
CE1
|
H:HIS488
|
3.2
|
42.6
|
1.0
|
CB
|
H:CYS479
|
3.2
|
52.1
|
1.0
|
CB
|
H:CYS482
|
3.4
|
47.7
|
1.0
|
N
|
H:CYS482
|
3.6
|
47.5
|
1.0
|
CA
|
H:CYS482
|
3.9
|
50.2
|
1.0
|
ND1
|
G:HIS49
|
4.0
|
48.9
|
1.0
|
CG
|
G:HIS49
|
4.1
|
45.9
|
1.0
|
CG
|
H:HIS488
|
4.2
|
42.0
|
1.0
|
ND1
|
H:HIS488
|
4.2
|
41.0
|
1.0
|
CB
|
G:CYS48
|
4.3
|
40.5
|
1.0
|
C
|
H:MET481
|
4.5
|
47.6
|
1.0
|
CA
|
H:CYS479
|
4.6
|
56.0
|
1.0
|
CB
|
H:MET481
|
4.7
|
48.4
|
1.0
|
C
|
H:CYS479
|
4.9
|
55.4
|
1.0
|
|
Zinc binding site 4 out
of 4 in 5we0
Go back to
Zinc Binding Sites List in 5we0
Zinc binding site 4 out
of 4 in the Structural Basis For Shelterin Bridge Assembly
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Structural Basis For Shelterin Bridge Assembly within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
J:Zn601
b:72.0
occ:1.00
|
NE2
|
K:HIS488
|
1.9
|
57.5
|
1.0
|
NE2
|
J:HIS49
|
2.2
|
62.8
|
1.0
|
SG
|
K:CYS482
|
2.4
|
69.7
|
1.0
|
SG
|
K:CYS479
|
2.5
|
75.2
|
1.0
|
CE1
|
K:HIS488
|
2.7
|
56.8
|
1.0
|
CE1
|
J:HIS49
|
2.9
|
62.5
|
1.0
|
CD2
|
K:HIS488
|
3.1
|
53.8
|
1.0
|
CB
|
K:CYS479
|
3.2
|
77.4
|
1.0
|
CD2
|
J:HIS49
|
3.2
|
58.3
|
1.0
|
CB
|
K:CYS482
|
3.4
|
79.0
|
1.0
|
N
|
K:CYS482
|
3.6
|
75.5
|
1.0
|
ND1
|
K:HIS488
|
3.9
|
58.1
|
1.0
|
CA
|
K:CYS482
|
3.9
|
78.5
|
1.0
|
ND1
|
J:HIS49
|
4.1
|
58.6
|
1.0
|
CG
|
K:HIS488
|
4.1
|
54.2
|
1.0
|
CG
|
J:HIS49
|
4.2
|
55.5
|
1.0
|
CB
|
J:CYS48
|
4.4
|
50.6
|
1.0
|
C
|
K:MET481
|
4.4
|
75.9
|
1.0
|
CB
|
K:MET481
|
4.5
|
70.8
|
1.0
|
CA
|
K:CYS479
|
4.7
|
83.6
|
1.0
|
CA
|
K:MET481
|
4.9
|
75.4
|
1.0
|
N
|
K:MET481
|
4.9
|
82.9
|
1.0
|
C
|
K:CYS479
|
5.0
|
82.0
|
1.0
|
|
Reference:
J.K.Kim,
J.Liu,
X.Hu,
C.Yu,
K.Roskamp,
B.Sankaran,
L.Huang,
E.A.Komives,
F.Qiao.
Structural Basis For Shelterin Bridge Assembly. Mol. Cell V. 68 698 2017.
ISSN: ISSN 1097-4164
PubMed: 29149597
DOI: 10.1016/J.MOLCEL.2017.10.032
Page generated: Mon Oct 28 14:07:30 2024
|