Zinc in PDB 5w57: Structure of Holo Aztc

The structure of Structure of Holo Aztc, PDB code: 5w57 was solved by D.Avalos, E.T.Yukl, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.92 / 2.30
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	104.840, 72.373, 105.613, 90.00, 96.55, 90.00
R / Rfree (%)	21.7 / 24.1

The binding sites of Zinc atom in the Structure of Holo Aztc (pdb code 5w57). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Holo Aztc, PDB code: 5w57:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of Holo Aztc


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Holo Aztc within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:44.7 occ:1.00 OD1 A:ASP279 2.0 53.5 1.0 NE2 A:HIS61 2.1 54.7 1.0 NE2 A:HIS138 2.2 53.0 1.0 NE2 A:HIS204 2.3 51.2 1.0 CG A:ASP279 2.8 46.2 1.0 CD2 A:HIS61 3.0 55.9 1.0 OD2 A:ASP279 3.0 40.7 1.0 CD2 A:HIS138 3.1 43.8 1.0 CD2 A:HIS204 3.1 42.6 1.0 CE1 A:HIS61 3.1 58.7 1.0 CE1 A:HIS138 3.3 52.1 1.0 CE1 A:HIS204 3.5 55.4 1.0 O A:VAL224 3.6 56.0 1.0 CB A:ALA206 4.0 37.4 1.0 CG A:HIS61 4.2 58.3 1.0 ND1 A:HIS61 4.2 56.5 1.0 O A:HOH501 4.2 51.9 1.0 CB A:ASP279 4.3 40.7 1.0 CG A:HIS138 4.3 49.9 1.0 CE1 A:PHE86 4.3 44.3 1.0 CG A:HIS204 4.3 45.4 1.0 ND1 A:HIS138 4.3 52.6 1.0 ND1 A:HIS204 4.5 54.3 1.0 C A:VAL224 4.7 49.0 1.0 CA A:ALA206 4.8 42.4 1.0

Zinc binding site 2 out of 2 in the Structure of Holo Aztc


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Holo Aztc within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn401 b:46.2 occ:1.00 OD1 B:ASP279 2.0 52.5 1.0 NE2 B:HIS61 2.0 55.2 1.0 NE2 B:HIS138 2.3 65.0 1.0 NE2 B:HIS204 2.3 45.2 1.0 CG B:ASP279 2.9 50.8 1.0 CD2 B:HIS61 2.9 52.5 1.0 CD2 B:HIS138 3.0 54.4 1.0 CE1 B:HIS61 3.0 52.8 1.0 OD2 B:ASP279 3.1 56.6 1.0 CD2 B:HIS204 3.2 47.6 1.0 CE1 B:HIS138 3.4 68.3 1.0 CE1 B:HIS204 3.4 47.8 1.0 O B:VAL224 3.6 51.5 1.0 CG B:HIS61 4.1 48.0 1.0 ND1 B:HIS61 4.1 52.5 1.0 CB B:ALA206 4.2 43.1 1.0 CG B:HIS138 4.2 59.5 1.0 CB B:ASP279 4.2 50.5 1.0 ND1 B:HIS138 4.3 69.8 1.0 CE1 B:PHE86 4.3 48.0 1.0 CG B:HIS204 4.4 48.0 1.0 O B:HOH512 4.4 48.9 1.0 ND1 B:HIS204 4.5 51.6 1.0 C B:VAL224 4.7 58.2 1.0 CA B:ALA206 4.9 53.0 1.0

D.P.Neupane, D.Avalos, S.Fullam, H.Roychowdhury, E.T.Yukl. Mechanisms of Zinc Binding to the Solute-Binding Protein Aztc and Transfer From the Metallochaperone Aztd. J. Biol. Chem. V. 292 17496 2017.
ISSN: ESSN 1083-351X
PubMed: 28887302
DOI: 10.1074/JBC.M117.804799