Zinc in PDB 5w0z: Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid)

All present enzymatic activity of Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid):
3.5.4.38;

The structure of Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid), PDB code: 5w0z was solved by Q.Qiao, L.Wang, H.Wu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.00 / 3.61
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	38.680, 167.650, 188.300, 90.00, 90.00, 90.00
R / Rfree (%)	27.4 / 30.7

The binding sites of Zinc atom in the Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid) (pdb code 5w0z). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid), PDB code: 5w0z:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn2001 b:80.3 occ:1.00 SG B:CYS1087 1.9 97.8 1.0 SG B:CYS1090 2.4 71.3 1.0 ND1 B:HIS1056 2.4 74.3 1.0 CB B:CYS1087 2.8 95.7 1.0 CB B:CYS1090 3.0 76.0 1.0 CE1 B:HIS1056 3.1 74.0 1.0 CG B:HIS1056 3.1 75.1 1.0 N B:CYS1087 3.6 93.1 1.0 CB B:HIS1056 3.6 76.8 1.0 CA B:CYS1087 3.7 95.1 1.0 NE2 B:HIS1056 3.9 74.0 1.0 CD2 B:HIS1056 3.9 74.2 1.0 N B:CYS1090 4.0 84.7 1.0 OE2 B:GLU1058 4.1 58.6 1.0 CA B:CYS1090 4.1 79.6 1.0 O B:CYS1087 4.3 94.0 1.0 C B:CYS1087 4.3 96.1 1.0 CD B:GLU1058 4.6 60.9 1.0 OE1 B:GLU1058 4.6 60.6 1.0 C B:PRO1086 4.8 88.0 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Mbp Fused Activation-Induced Cytidine Deaminase (Aid) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2001 b:43.4 occ:1.00 SG A:CYS1087 1.9 59.2 1.0 SG A:CYS1090 2.2 47.7 1.0 ND1 A:HIS1056 2.3 59.4 1.0 CB A:CYS1087 2.9 59.1 1.0 CB A:CYS1090 3.0 50.8 1.0 CE1 A:HIS1056 3.1 59.9 1.0 CG A:HIS1056 3.1 57.9 1.0 CB A:HIS1056 3.5 57.7 1.0 N A:CYS1087 3.8 59.9 1.0 CA A:CYS1087 3.9 59.9 1.0 N A:CYS1090 3.9 58.9 1.0 CA A:CYS1090 4.0 53.3 1.0 NE2 A:HIS1056 4.1 59.0 1.0 CD2 A:HIS1056 4.1 58.0 1.0 OE2 A:GLU1058 4.3 47.5 1.0 O A:CYS1087 4.3 62.8 1.0 C A:CYS1087 4.4 62.0 1.0 CD A:GLU1058 4.7 48.7 1.0 OE1 A:GLU1058 4.7 49.4 1.0 CA A:HIS1056 5.0 58.7 1.0

Q.Qiao, L.Wang, F.L.Meng, J.K.Hwang, F.W.Alt, H.Wu. Aid Recognizes Structured Dna For Class Switch Recombination. Mol. Cell V. 67 361 2017.
ISSN: ISSN 1097-4164
PubMed: 28757211
DOI: 10.1016/J.MOLCEL.2017.06.034