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Atomistry » Zinc » PDB 5v37-5vdu » 5v8o | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 5v37-5vdu » 5v8o » |
Zinc in PDB 5v8o: Discovery of A High Affinity Inhibitor of CgasEnzymatic activity of Discovery of A High Affinity Inhibitor of Cgas
All present enzymatic activity of Discovery of A High Affinity Inhibitor of Cgas:
2.7.7.86; Protein crystallography data
The structure of Discovery of A High Affinity Inhibitor of Cgas, PDB code: 5v8o
was solved by
J.Hall,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Discovery of A High Affinity Inhibitor of Cgas
(pdb code 5v8o). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Discovery of A High Affinity Inhibitor of Cgas, PDB code: 5v8o: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 5v8oGo back to Zinc Binding Sites List in 5v8o
Zinc binding site 1 out
of 2 in the Discovery of A High Affinity Inhibitor of Cgas
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 5v8oGo back to Zinc Binding Sites List in 5v8o
Zinc binding site 2 out
of 2 in the Discovery of A High Affinity Inhibitor of Cgas
Mono view Stereo pair view
Reference:
J.Hall,
A.Brault,
F.Vincent,
S.Weng,
H.Wang,
D.Dumlao,
A.Aulabaugh,
D.Aivazian,
D.Castro,
M.Chen,
J.Culp,
K.Dower,
J.Gardner,
S.Hawrylik,
D.Golenbock,
D.Hepworth,
M.Horn,
L.Jones,
P.Jones,
E.Latz,
J.Li,
L.L.Lin,
W.Lin,
D.Lin,
F.Lovering,
N.Niljanskul,
R.Nistler,
B.Pierce,
O.Plotnikova,
D.Schmitt,
S.Shanker,
J.Smith,
W.Snyder,
T.Subashi,
J.Trujillo,
E.Tyminski,
G.Wang,
J.Wong,
B.Lefker,
L.Dakin,
K.Leach.
Discovery of Pf-06928215 As A High Affinity Inhibitor of Cgas Enabled By A Novel Fluorescence Polarization Assay. Plos One V. 12 84843 2017.
Page generated: Mon Oct 28 12:38:26 2024
ISSN: ESSN 1932-6203 PubMed: 28934246 DOI: 10.1371/JOURNAL.PONE.0184843 |
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