Atomistry » Zinc » PDB 5tmh-5ty2 » 5tpw
Atomistry »
  Zinc »
    PDB 5tmh-5ty2 »
      5tpw »

Zinc in PDB 5tpw: Crystal Structure of Amino Terminal Domains of the Nmda Receptor Subunit GLUN1 and GLUN2A in Complex with Zinc at the GLUN2A

Protein crystallography data

The structure of Crystal Structure of Amino Terminal Domains of the Nmda Receptor Subunit GLUN1 and GLUN2A in Complex with Zinc at the GLUN2A, PDB code: 5tpw was solved by A.Romero-Hernandez, N.Simorowski, E.Karakas, H.Furukawa, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.56 / 2.91
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 79.560, 118.401, 155.812, 90.00, 90.00, 90.00
R / Rfree (%) 20 / 24.5

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Amino Terminal Domains of the Nmda Receptor Subunit GLUN1 and GLUN2A in Complex with Zinc at the GLUN2A (pdb code 5tpw). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Amino Terminal Domains of the Nmda Receptor Subunit GLUN1 and GLUN2A in Complex with Zinc at the GLUN2A, PDB code: 5tpw:

Zinc binding site 1 out of 1 in 5tpw

Go back to Zinc Binding Sites List in 5tpw
Zinc binding site 1 out of 1 in the Crystal Structure of Amino Terminal Domains of the Nmda Receptor Subunit GLUN1 and GLUN2A in Complex with Zinc at the GLUN2A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Amino Terminal Domains of the Nmda Receptor Subunit GLUN1 and GLUN2A in Complex with Zinc at the GLUN2A within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn401

b:58.1
occ:0.49
OE2 B:GLU266 2.0 46.6 1.0
OD2 B:ASP282 2.0 74.8 1.0
NE2 B:HIS128 2.0 65.3 1.0
OD1 B:ASP282 2.0 91.6 1.0
NE2 B:HIS44 2.1 58.3 1.0
CG B:ASP282 2.3 72.4 1.0
CE1 B:HIS44 2.8 66.9 1.0
CD2 B:HIS128 2.9 63.4 1.0
CE1 B:HIS128 3.2 51.6 1.0
CD B:GLU266 3.2 64.7 1.0
CD2 B:HIS44 3.3 84.2 1.0
CB B:ASP282 3.9 59.0 1.0
ND1 B:HIS44 4.0 72.7 1.0
CG B:GLU266 4.1 64.0 1.0
CG B:HIS128 4.1 44.7 1.0
OE1 B:GLU266 4.1 68.1 1.0
ND1 B:HIS128 4.2 51.5 1.0
CG B:HIS44 4.3 80.0 1.0
O B:ASP282 4.4 74.9 1.0
CA B:ASP282 4.7 67.9 1.0
C B:ASP282 4.7 63.0 1.0

Reference:

A.Romero-Hernandez, N.Simorowski, E.Karakas, H.Furukawa. Molecular Basis For Subtype Specificity and High-Affinity Zinc Inhibition in the GLUN1-GLUN2A Nmda Receptor Amino-Terminal Domain. Neuron V. 92 1324 2016.
ISSN: ISSN 1097-4199
PubMed: 27916457
DOI: 10.1016/J.NEURON.2016.11.006
Page generated: Wed Dec 16 10:56:33 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy