Zinc in PDB 5oa3: Human 40S-EIF2D-Re-Initiation Complex

All present enzymatic activity of Human 40S-EIF2D-Re-Initiation Complex:
4.2.99.18;

The binding sites of Zinc atom in the Human 40S-EIF2D-Re-Initiation Complex (pdb code 5oa3). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Human 40S-EIF2D-Re-Initiation Complex, PDB code: 5oa3:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Human 40S-EIF2D-Re-Initiation Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human 40S-EIF2D-Re-Initiation Complex within 5.0Å range: probe atom residue distance (Å) B Occ a:Zn201 b:44.9 occ:1.00 SG a:CYS77 2.3 29.4 1.0 SG a:CYS26 2.3 32.5 1.0 CB a:CYS26 2.4 32.5 1.0 SG a:CYS74 2.4 31.5 1.0 SG a:CYS23 2.6 30.7 1.0 CB a:CYS77 3.2 29.4 1.0 CA a:CYS26 3.5 30.9 1.0 CB a:CYS74 3.6 31.5 1.0 N a:CYS26 3.6 30.9 1.0 CB a:CYS23 3.9 30.7 1.0 N a:CYS74 4.1 28.5 1.0 N a:CYS77 4.3 26.1 1.0 CA a:CYS77 4.3 26.1 1.0 CA a:CYS74 4.3 28.5 1.0 O a:CYS74 4.5 28.5 1.0 CB a:ARG28 4.5 27.5 1.0 C a:ASN25 4.7 32.7 1.0 CB a:ASN25 4.7 37.2 1.0 C a:CYS26 4.7 30.9 1.0 C a:CYS74 4.8 28.5 1.0

Zinc binding site 2 out of 3 in the Human 40S-EIF2D-Re-Initiation Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Human 40S-EIF2D-Re-Initiation Complex within 5.0Å range: probe atom residue distance (Å) B Occ d:Zn201 b:0.4 occ:1.00 SG d:CYS39 2.3 0.3 1.0 SG d:CYS24 2.3 0.7 1.0 SG d:CYS21 2.4 0.5 1.0 SG d:CYS42 2.4 0.4 1.0 CB d:CYS21 3.2 0.5 1.0 CB d:CYS24 3.5 0.7 1.0 CB d:CYS42 3.7 0.4 1.0 N d:CYS24 3.9 0.7 1.0 CB d:CYS39 4.0 0.3 1.0 N d:CYS39 4.1 0.8 1.0 O2' 2:G1495 4.2 0.4 1.0 CA d:CYS24 4.3 0.7 1.0 CA d:CYS39 4.6 0.8 1.0 CB d:VAL23 4.6 0.3 1.0 O d:CYS39 4.6 0.8 1.0 N d:CYS42 4.7 0.8 1.0 CA d:CYS21 4.7 0.8 1.0 CA d:CYS42 4.8 0.8 1.0 C d:CYS24 4.9 0.7 1.0 C d:CYS39 5.0 0.8 1.0

Zinc binding site 3 out of 3 in the Human 40S-EIF2D-Re-Initiation Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Human 40S-EIF2D-Re-Initiation Complex within 5.0Å range: probe atom residue distance (Å) B Occ f:Zn500 b:0.2 occ:1.00 SG f:CYS126 2.3 0.2 1.0 SG f:CYS144 2.3 0.5 1.0 SG f:CYS121 2.4 0.9 1.0 SG f:CYS141 2.4 1.0 1.0 CB f:CYS141 3.3 1.0 1.0 CB f:CYS121 3.4 0.9 1.0 CB f:CYS144 3.8 0.5 1.0 CB f:CYS126 3.8 0.2 1.0 CB f:SER123 3.9 0.8 1.0 N f:CYS144 4.1 0.2 1.0 OG f:SER123 4.2 0.8 1.0 CA f:CYS144 4.5 0.2 1.0 CB f:LYS143 4.7 0.3 1.0 CA f:CYS141 4.7 0.3 1.0 CB f:LEU146 4.8 0.6 1.0 CA f:CYS121 4.9 0.3 1.0 N f:SER123 5.0 0.8 1.0

M.Weisser, T.Schafer, M.Leibundgut, D.Bohringer, C.H.S.Aylett, N.Ban. Structural and Functional Insights Into Human Re-Initiation Complexes. Mol. Cell V. 67 447 2017.
ISSN: ISSN 1097-4164
PubMed: 28732596
DOI: 10.1016/J.MOLCEL.2017.06.032