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Zinc in PDB 5n1r: Crystal Structure of Human Carbonic Anhydrase II in Complex with the Inhibitor 4'-Pyrazol-1-Ylmethyl-Biphenyl-4-SulfonamideEnzymatic activity of Crystal Structure of Human Carbonic Anhydrase II in Complex with the Inhibitor 4'-Pyrazol-1-Ylmethyl-Biphenyl-4-Sulfonamide
All present enzymatic activity of Crystal Structure of Human Carbonic Anhydrase II in Complex with the Inhibitor 4'-Pyrazol-1-Ylmethyl-Biphenyl-4-Sulfonamide:
4.2.1.1; Protein crystallography data
The structure of Crystal Structure of Human Carbonic Anhydrase II in Complex with the Inhibitor 4'-Pyrazol-1-Ylmethyl-Biphenyl-4-Sulfonamide, PDB code: 5n1r
was solved by
M.Ferraroni,
C.T.Supuran,
A.Scozzafava,
F.Carta,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Carbonic Anhydrase II in Complex with the Inhibitor 4'-Pyrazol-1-Ylmethyl-Biphenyl-4-Sulfonamide
(pdb code 5n1r). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Carbonic Anhydrase II in Complex with the Inhibitor 4'-Pyrazol-1-Ylmethyl-Biphenyl-4-Sulfonamide, PDB code: 5n1r: Zinc binding site 1 out of 1 in 5n1rGo back to Zinc Binding Sites List in 5n1r
Zinc binding site 1 out
of 1 in the Crystal Structure of Human Carbonic Anhydrase II in Complex with the Inhibitor 4'-Pyrazol-1-Ylmethyl-Biphenyl-4-Sulfonamide
Mono view Stereo pair view
Reference:
M.Ferraroni,
B.Cornelio,
J.Sapi,
C.T.Supuran,
A.Scozzafava.
Sulfonamide Carbonic Anhydrase Inhibitors: Zinc Coordination and Tail Effects Influence Inhibitory Efficacy and Selectivity For Different Isoforms Inorg.Chim.Acta. V. 470 128 2018.
Page generated: Wed Dec 16 06:34:10 2020
ISSN: ISSN 0020-1693 DOI: 10.1016/J.ICA.2017.03.038 |
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