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Atomistry » Zinc » PDB 5jez-5jmx » 5jgt » |
Zinc in PDB 5jgt: Human Carbonic Anhydrase II (F131Y/L198A) Complexed with 1,3-Thiazole- 2-SulfonamideEnzymatic activity of Human Carbonic Anhydrase II (F131Y/L198A) Complexed with 1,3-Thiazole- 2-Sulfonamide
All present enzymatic activity of Human Carbonic Anhydrase II (F131Y/L198A) Complexed with 1,3-Thiazole- 2-Sulfonamide:
4.2.1.1; Protein crystallography data
The structure of Human Carbonic Anhydrase II (F131Y/L198A) Complexed with 1,3-Thiazole- 2-Sulfonamide, PDB code: 5jgt
was solved by
J.M.Fox,
K.Kang,
M.Sastry,
W.Sherman,
B.Sankaran,
P.H.Zwart,
G.M.Whitesides,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Human Carbonic Anhydrase II (F131Y/L198A) Complexed with 1,3-Thiazole- 2-Sulfonamide
(pdb code 5jgt). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human Carbonic Anhydrase II (F131Y/L198A) Complexed with 1,3-Thiazole- 2-Sulfonamide, PDB code: 5jgt: Zinc binding site 1 out of 1 in 5jgtGo back to Zinc Binding Sites List in 5jgt
Zinc binding site 1 out
of 1 in the Human Carbonic Anhydrase II (F131Y/L198A) Complexed with 1,3-Thiazole- 2-Sulfonamide
Mono view Stereo pair view
Reference:
J.M.Fox,
K.Kang,
M.Sastry,
W.Sherman,
B.Sankaran,
P.H.Zwart,
G.M.Whitesides.
Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase. Angew. Chem. Int. Ed. Engl. V. 56 3833 2017.
Page generated: Wed Dec 16 06:25:11 2020
ISSN: ESSN 1521-3773 PubMed: 28252841 DOI: 10.1002/ANIE.201609409 |
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