Atomistry » Zinc » PDB 5hou-5i3a » 5i2d
Atomistry »
  Zinc »
    PDB 5hou-5i3a »
      5i2d »

Zinc in PDB 5i2d: Crystal Structure of T. Thermophilus TTHB099 Class II Transcription Activation Complex: Tap-Rpo

Enzymatic activity of Crystal Structure of T. Thermophilus TTHB099 Class II Transcription Activation Complex: Tap-Rpo

All present enzymatic activity of Crystal Structure of T. Thermophilus TTHB099 Class II Transcription Activation Complex: Tap-Rpo:
2.7.7.6;

Protein crystallography data

The structure of Crystal Structure of T. Thermophilus TTHB099 Class II Transcription Activation Complex: Tap-Rpo, PDB code: 5i2d was solved by Y.Feng, Y.Zhang, R.H.Ebright, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 49.31 / 4.41
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 171.487, 105.446, 374.585, 90.00, 102.39, 90.00
R / Rfree (%) 24.1 / 28.4

Other elements in 5i2d:

The structure of Crystal Structure of T. Thermophilus TTHB099 Class II Transcription Activation Complex: Tap-Rpo also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of T. Thermophilus TTHB099 Class II Transcription Activation Complex: Tap-Rpo (pdb code 5i2d). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of T. Thermophilus TTHB099 Class II Transcription Activation Complex: Tap-Rpo, PDB code: 5i2d:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in 5i2d

Go back to Zinc Binding Sites List in 5i2d
Zinc binding site 1 out of 4 in the Crystal Structure of T. Thermophilus TTHB099 Class II Transcription Activation Complex: Tap-Rpo


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of T. Thermophilus TTHB099 Class II Transcription Activation Complex: Tap-Rpo within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn2001

b:52.6
occ:1.00
SG D:CYS1112 2.3 63.2 1.0
SG D:CYS1201 2.3 77.4 1.0
SG D:CYS1194 2.3 74.2 1.0
SG D:CYS1204 2.3 0.8 1.0
CB D:CYS1204 3.2 0.6 1.0
CB D:CYS1194 3.2 74.8 1.0
CA D:CYS1194 3.5 73.9 1.0
CB D:CYS1112 3.6 62.8 1.0
CB D:CYS1201 3.6 89.3 1.0
OG1 D:THR1196 3.8 0.2 1.0
N D:GLN1195 3.9 60.8 1.0
C D:CYS1194 4.2 76.3 1.0
N D:CYS1112 4.2 68.6 1.0
N D:CYS1201 4.2 87.1 1.0
CG2 D:THR1114 4.2 78.4 1.0
CA D:CYS1204 4.4 0.4 1.0
N D:CYS1204 4.5 0.2 1.0
CA D:CYS1201 4.5 85.4 1.0
CA D:CYS1112 4.5 69.1 1.0
N D:THR1196 4.6 98.5 1.0
NH2 D:ARG1189 4.7 0.9 1.0
N D:CYS1194 4.7 69.7 1.0
CB D:THR1196 4.9 0.8 1.0

Zinc binding site 2 out of 4 in 5i2d

Go back to Zinc Binding Sites List in 5i2d
Zinc binding site 2 out of 4 in the Crystal Structure of T. Thermophilus TTHB099 Class II Transcription Activation Complex: Tap-Rpo


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of T. Thermophilus TTHB099 Class II Transcription Activation Complex: Tap-Rpo within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn2002

b:49.2
occ:1.00
SG D:CYS73 2.3 62.6 1.0
SG D:CYS76 2.3 86.4 1.0
SG D:CYS60 2.3 51.0 1.0
SG D:CYS58 2.3 57.6 1.0
CB D:CYS73 2.8 53.5 1.0
CB D:CYS58 3.2 60.1 1.0
CB D:CYS76 3.4 84.7 1.0
N D:CYS60 3.7 54.0 1.0
CB D:CYS60 3.7 50.8 1.0
N D:CYS76 4.0 92.9 1.0
N D:GLY61 4.1 73.0 1.0
N D:LYS62 4.1 81.1 1.0
CA D:CYS60 4.1 54.9 1.0
N D:ALA59 4.2 72.4 1.0
CB D:LYS62 4.2 77.3 1.0
CA D:CYS76 4.3 84.1 1.0
CA D:CYS73 4.3 55.0 1.0
CA D:CYS58 4.4 60.2 1.0
C D:CYS58 4.5 58.6 1.0
C D:CYS60 4.5 63.5 1.0
C D:ALA59 4.7 80.5 1.0
CA D:LYS62 4.8 74.3 1.0
CD1 D:TYR63 4.8 72.9 1.0
CB D:ARG75 4.8 94.0 1.0
C D:CYS73 4.9 61.8 1.0
CA D:ALA59 4.9 72.3 1.0

Zinc binding site 3 out of 4 in 5i2d

Go back to Zinc Binding Sites List in 5i2d
Zinc binding site 3 out of 4 in the Crystal Structure of T. Thermophilus TTHB099 Class II Transcription Activation Complex: Tap-Rpo


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of T. Thermophilus TTHB099 Class II Transcription Activation Complex: Tap-Rpo within 5.0Å range:
probe atom residue distance (Å) B Occ
O:Zn2001

b:53.9
occ:1.00
SG O:CYS1112 2.3 59.7 1.0
SG O:CYS1194 2.3 42.1 1.0
SG O:CYS1201 2.3 39.3 1.0
SG O:CYS1204 2.3 77.4 1.0
CB O:CYS1194 3.2 42.7 1.0
CB O:CYS1204 3.2 77.1 1.0
CA O:CYS1194 3.4 41.8 1.0
CB O:CYS1112 3.5 59.2 1.0
CB O:CYS1201 3.6 51.2 1.0
OG1 O:THR1196 3.7 0.5 1.0
N O:GLN1195 3.8 58.1 1.0
C O:CYS1194 4.1 44.1 1.0
N O:CYS1112 4.2 65.1 1.0
CG2 O:THR1114 4.2 51.2 1.0
N O:CYS1201 4.3 49.0 1.0
CA O:CYS1204 4.4 78.9 1.0
N O:CYS1204 4.4 79.7 1.0
CA O:CYS1112 4.5 65.6 1.0
CA O:CYS1201 4.5 47.3 1.0
NH2 O:ARG1189 4.5 88.5 1.0
N O:THR1196 4.6 0.8 1.0
N O:CYS1194 4.7 37.6 1.0
CB O:THR1196 4.9 0.1 1.0
OD1 O:ASP1111 5.0 84.4 1.0

Zinc binding site 4 out of 4 in 5i2d

Go back to Zinc Binding Sites List in 5i2d
Zinc binding site 4 out of 4 in the Crystal Structure of T. Thermophilus TTHB099 Class II Transcription Activation Complex: Tap-Rpo


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of T. Thermophilus TTHB099 Class II Transcription Activation Complex: Tap-Rpo within 5.0Å range:
probe atom residue distance (Å) B Occ
O:Zn2002

b:65.6
occ:1.00
SG O:CYS60 2.3 93.0 1.0
SG O:CYS73 2.3 56.6 1.0
SG O:CYS76 2.3 0.4 1.0
SG O:CYS58 2.3 69.5 1.0
CB O:CYS73 3.1 47.4 1.0
CB O:CYS58 3.2 72.1 1.0
CB O:CYS76 3.3 0.7 1.0
N O:CYS60 3.6 96.1 1.0
CB O:CYS60 3.6 92.9 1.0
N O:CYS76 3.9 0.9 1.0
N O:GLY61 4.0 89.5 1.0
CA O:CYS60 4.0 96.9 1.0
N O:LYS62 4.1 88.2 1.0
N O:ALA59 4.1 57.5 1.0
CA O:CYS76 4.2 0.1 1.0
CB O:LYS62 4.2 84.4 1.0
C O:CYS60 4.4 0.6 1.0
C O:CYS58 4.4 70.5 1.0
CA O:CYS58 4.4 72.1 1.0
CA O:CYS73 4.5 48.9 1.0
C O:ALA59 4.6 65.6 1.0
CB O:ARG75 4.7 89.3 1.0
CA O:LYS62 4.7 81.4 1.0
CA O:ALA59 4.8 57.4 1.0
CD1 O:TYR63 4.9 50.0 1.0
C O:ARG75 4.9 97.3 1.0
CA O:GLY61 5.0 93.4 1.0

Reference:

Y.Feng, Y.Zhang, R.H.Ebright. Structural Basis of Transcription Activation. Science V. 352 1330 2016.
ISSN: ESSN 1095-9203
PubMed: 27284196
DOI: 10.1126/SCIENCE.AAF4417
Page generated: Sun Oct 27 17:47:45 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy