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Atomistry » Zinc » PDB 5hou-5i3a » 5i12 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 5hou-5i3a » 5i12 » |
Zinc in PDB 5i12: Crystal Structure of the Catalytic Domain of Mmp-9 in Complex with A Selective Sugar-Conjugated Arylsulfonamide Carboxylate Water-Soluble Inhibitor (DC27).Enzymatic activity of Crystal Structure of the Catalytic Domain of Mmp-9 in Complex with A Selective Sugar-Conjugated Arylsulfonamide Carboxylate Water-Soluble Inhibitor (DC27).
All present enzymatic activity of Crystal Structure of the Catalytic Domain of Mmp-9 in Complex with A Selective Sugar-Conjugated Arylsulfonamide Carboxylate Water-Soluble Inhibitor (DC27).:
3.4.24.35; Protein crystallography data
The structure of Crystal Structure of the Catalytic Domain of Mmp-9 in Complex with A Selective Sugar-Conjugated Arylsulfonamide Carboxylate Water-Soluble Inhibitor (DC27)., PDB code: 5i12
was solved by
E.A.Stura,
L.Rosalia,
D.Cuffaro,
L.Tepshi,
L.Ciccone,
A.Rossello,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5i12:
The structure of Crystal Structure of the Catalytic Domain of Mmp-9 in Complex with A Selective Sugar-Conjugated Arylsulfonamide Carboxylate Water-Soluble Inhibitor (DC27). also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of the Catalytic Domain of Mmp-9 in Complex with A Selective Sugar-Conjugated Arylsulfonamide Carboxylate Water-Soluble Inhibitor (DC27).
(pdb code 5i12). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Catalytic Domain of Mmp-9 in Complex with A Selective Sugar-Conjugated Arylsulfonamide Carboxylate Water-Soluble Inhibitor (DC27)., PDB code: 5i12: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 5i12Go back to Zinc Binding Sites List in 5i12
Zinc binding site 1 out
of 2 in the Crystal Structure of the Catalytic Domain of Mmp-9 in Complex with A Selective Sugar-Conjugated Arylsulfonamide Carboxylate Water-Soluble Inhibitor (DC27).
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 5i12Go back to Zinc Binding Sites List in 5i12
Zinc binding site 2 out
of 2 in the Crystal Structure of the Catalytic Domain of Mmp-9 in Complex with A Selective Sugar-Conjugated Arylsulfonamide Carboxylate Water-Soluble Inhibitor (DC27).
Mono view Stereo pair view
Reference:
E.Nuti,
D.Cuffaro,
F.D'andrea,
L.Rosalia,
L.Tepshi,
M.Fabbi,
G.Carbotti,
S.Ferrini,
S.Santamaria,
C.Camodeca,
L.Ciccone,
E.Orlandini,
S.Nencetti,
E.A.Stura,
V.Dive,
A.Rossello.
Sugar-Based Arylsulfonamide Carboxylates As Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors. Chemmedchem V. 11 1626 2016.
Page generated: Sun Oct 27 17:44:56 2024
ISSN: ESSN 1860-7187 PubMed: 27356908 DOI: 10.1002/CMDC.201600235 |
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