Zinc in PDB 5hkx: Crystal Structure of C-Cbl Tkbd-Ring Domains (Y371E Mutant) Refined to 1.85 A Resolution

The structure of Crystal Structure of C-Cbl Tkbd-Ring Domains (Y371E Mutant) Refined to 1.85 A Resolution, PDB code: 5hkx was solved by S.Lovell, K.P.Battaile, N.Mehzabeen, N.Zhang, A.Cooper, P.Gao, R.P.Perez, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.47 / 1.85
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	44.075, 108.737, 49.304, 90.00, 115.31, 90.00
R / Rfree (%)	16.7 / 21.4

The structure of Crystal Structure of C-Cbl Tkbd-Ring Domains (Y371E Mutant) Refined to 1.85 A Resolution also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Zinc atom in the Crystal Structure of C-Cbl Tkbd-Ring Domains (Y371E Mutant) Refined to 1.85 A Resolution (pdb code 5hkx). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of C-Cbl Tkbd-Ring Domains (Y371E Mutant) Refined to 1.85 A Resolution, PDB code: 5hkx:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of C-Cbl Tkbd-Ring Domains (Y371E Mutant) Refined to 1.85 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of C-Cbl Tkbd-Ring Domains (Y371E Mutant) Refined to 1.85 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn502 b:21.8 occ:1.00 ND1 A:HIS398 2.0 17.6 1.0 SG A:CYS396 2.3 24.2 1.0 SG A:CYS416 2.3 19.8 1.0 SG A:CYS419 2.4 22.2 1.0 CE1 A:HIS398 2.9 22.0 1.0 CB A:CYS416 3.1 19.4 1.0 CG A:HIS398 3.1 20.5 1.0 CB A:CYS396 3.1 29.9 1.0 CB A:HIS398 3.5 19.8 1.0 CB A:CYS419 3.5 22.8 1.0 N A:CYS419 3.9 27.4 1.0 NE2 A:HIS398 4.1 25.2 1.0 CD2 A:HIS398 4.2 22.0 1.0 CA A:CYS419 4.3 26.0 1.0 CB A:PHE418 4.4 20.9 1.0 CA A:CYS396 4.5 22.8 1.0 CA A:CYS416 4.6 21.3 1.0 N A:HIS398 4.6 21.7 1.0 CA A:HIS398 4.7 27.0 1.0 O A:HOH795 4.7 37.5 1.0 CB A:CYS421 4.8 35.2 1.0 C A:PHE418 4.9 27.7 1.0 N A:PHE418 4.9 19.6 1.0 C A:CYS396 4.9 25.8 1.0 C A:CYS419 4.9 20.5 1.0 CA A:PHE418 5.0 19.9 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of C-Cbl Tkbd-Ring Domains (Y371E Mutant) Refined to 1.85 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of C-Cbl Tkbd-Ring Domains (Y371E Mutant) Refined to 1.85 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn503 b:19.9 occ:1.00 SG A:CYS401 2.3 20.8 1.0 SG A:CYS404 2.3 21.0 1.0 SG A:CYS381 2.3 18.7 1.0 SG A:CYS384 2.4 19.1 1.0 CB A:CYS381 3.1 20.7 1.0 CB A:CYS404 3.3 23.5 1.0 CB A:CYS384 3.3 25.7 1.0 CB A:CYS401 3.5 21.2 1.0 N A:CYS384 3.7 21.2 1.0 N A:CYS401 4.0 19.5 1.0 CA A:CYS384 4.1 22.1 1.0 N A:CYS404 4.2 26.1 1.0 CA A:CYS401 4.3 23.0 1.0 CA A:CYS404 4.3 25.9 1.0 CB A:ILE383 4.5 17.6 1.0 CA A:CYS381 4.5 20.5 1.0 ND2 A:ASN387 4.6 25.9 1.0 O A:CYS401 4.6 20.6 1.0 O A:HOH689 4.6 29.6 1.0 CB A:ASN387 4.6 22.5 1.0 C A:ILE383 4.7 30.3 1.0 C A:CYS381 4.7 19.2 1.0 O A:CYS381 4.7 20.1 1.0 C A:CYS401 4.8 21.8 1.0 N A:ILE383 4.8 17.1 1.0 CA A:ILE383 4.9 19.3 1.0 O A:ASN387 5.0 21.3 1.0

N.Zhang, D.Ferris, S.Lovell, A.Smalter-Hall, K.P.Battaile, A.Anbanandam, P.Gao, R.Hanzlik, R.P.Perez. Crystal Structure of C-Cbl Tkbd-Ring Domains (Y371E Mutant) Refined to 1.85 A Resolution To Be Published.