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Atomistry » Zinc » PDB 5fvu-5fz5 » 5fvy » |
Zinc in PDB 5fvy: Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with 4-Methyl-6-(2-(5-(4-Methylpiperazin- 1-Yl)Pyridin-3-Yl)Ethyl)Pyridin-2-AmineEnzymatic activity of Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with 4-Methyl-6-(2-(5-(4-Methylpiperazin- 1-Yl)Pyridin-3-Yl)Ethyl)Pyridin-2-Amine
All present enzymatic activity of Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with 4-Methyl-6-(2-(5-(4-Methylpiperazin- 1-Yl)Pyridin-3-Yl)Ethyl)Pyridin-2-Amine:
1.14.13.39; Protein crystallography data
The structure of Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with 4-Methyl-6-(2-(5-(4-Methylpiperazin- 1-Yl)Pyridin-3-Yl)Ethyl)Pyridin-2-Amine, PDB code: 5fvy
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5fvy:
The structure of Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with 4-Methyl-6-(2-(5-(4-Methylpiperazin- 1-Yl)Pyridin-3-Yl)Ethyl)Pyridin-2-Amine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with 4-Methyl-6-(2-(5-(4-Methylpiperazin- 1-Yl)Pyridin-3-Yl)Ethyl)Pyridin-2-Amine
(pdb code 5fvy). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with 4-Methyl-6-(2-(5-(4-Methylpiperazin- 1-Yl)Pyridin-3-Yl)Ethyl)Pyridin-2-Amine, PDB code: 5fvy: Zinc binding site 1 out of 1 in 5fvyGo back to Zinc Binding Sites List in 5fvy
Zinc binding site 1 out
of 1 in the Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with 4-Methyl-6-(2-(5-(4-Methylpiperazin- 1-Yl)Pyridin-3-Yl)Ethyl)Pyridin-2-Amine
Mono view Stereo pair view
Reference:
H.Wang,
Y.Qin,
H.Li,
L.J.Roman,
P.Martasek,
T.L.Poulos,
R.B.Silverman.
Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition By Optimization of the 2-Aminopyridine-Based Scaffold with A Pyridine Linker. J.Med.Chem. V. 59 4913 2016.
Page generated: Sun Oct 27 16:34:57 2024
ISSN: ISSN 0022-2623 PubMed: 27050842 DOI: 10.1021/ACS.JMEDCHEM.6B00273 |
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