Zinc in PDB 5fs0: Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr with 2,4-Dichlorophenol

The structure of Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr with 2,4-Dichlorophenol, PDB code: 5fs0 was solved by V.V.Patil, E.J.Woo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.35 / 2.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	46.693, 70.872, 104.852, 90.00, 90.00, 90.00
R / Rfree (%)	18.1 / 25.8

The structure of Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr with 2,4-Dichlorophenol also contains other interesting chemical elements:

Chlorine

(Cl)

4 atoms

The binding sites of Zinc atom in the Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr with 2,4-Dichlorophenol (pdb code 5fs0). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr with 2,4-Dichlorophenol, PDB code: 5fs0:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr with 2,4-Dichlorophenol


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr with 2,4-Dichlorophenol within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1210 b:42.4 occ:1.00 OE1 A:GLU174 2.1 42.5 1.0 SG A:CYS185 2.2 46.0 1.0 SG A:CYS151 2.3 39.8 1.0 SG A:CYS177 2.4 47.7 1.0 CD A:GLU174 3.1 40.4 1.0 CB A:CYS151 3.2 35.8 1.0 OE2 A:GLU174 3.4 41.5 1.0 CB A:CYS177 3.4 47.6 1.0 CB A:CYS185 3.5 52.3 1.0 CA A:CYS177 3.7 51.5 1.0 N A:CYS151 4.0 37.0 1.0 N A:VAL178 4.2 57.7 1.0 CA A:CYS151 4.2 34.1 1.0 C A:CYS177 4.4 58.1 1.0 CG A:GLU174 4.4 36.2 1.0 CG2 A:VAL178 4.5 57.6 1.0 CA A:CYS185 4.6 52.5 1.0 O A:GLU176 4.6 57.6 1.0 N A:VAL150 4.7 38.9 1.0 CE3 A:TRP130 4.7 35.4 1.0 N A:GLY179 4.8 59.2 1.0 N A:CYS177 5.0 60.5 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr with 2,4-Dichlorophenol


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr with 2,4-Dichlorophenol within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1209 b:42.9 occ:1.00 OE2 B:GLU174 1.9 40.1 1.0 SG B:CYS185 2.3 44.9 1.0 SG B:CYS151 2.4 34.6 1.0 SG B:CYS177 2.5 44.3 1.0 CD B:GLU174 3.0 44.9 1.0 CB B:CYS177 3.3 45.8 1.0 OE1 B:GLU174 3.4 43.8 1.0 CB B:CYS185 3.4 44.9 1.0 CB B:CYS151 3.5 36.8 1.0 CA B:CYS177 3.6 46.7 1.0 N B:VAL178 4.0 51.2 1.0 N B:CYS151 4.2 38.3 1.0 C B:CYS177 4.2 52.5 1.0 CG B:GLU174 4.3 39.8 1.0 CG2 B:VAL178 4.4 46.6 1.0 CA B:CYS151 4.5 37.5 1.0 CE3 B:TRP130 4.5 36.7 1.0 CA B:CYS185 4.5 41.8 1.0 O B:GLU176 4.6 46.3 1.0 OG B:SER133 4.7 46.4 1.0 CB B:SER133 4.7 36.7 1.0 N B:VAL150 4.7 45.6 1.0 N B:GLY179 4.7 53.4 1.0 CG2 B:VAL150 4.8 43.7 1.0 N B:CYS177 4.8 46.1 1.0 CZ3 B:TRP130 4.8 41.5 1.0

V.V.Patil, K.Park, S.Lee, E.Woo. Structural Analysis of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr Structure V. 624 24 2016.
ISSN: ISSN 0969-2126
PubMed: 27050690
DOI: 10.1016/J.STR.2016.03.006