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Atomistry » Zinc » PDB 5fpb-5fvt » 5fpl » |
Zinc in PDB 5fpl: Crystal Structure of Human JARID1B in Complex with CCT363901Protein crystallography data
The structure of Crystal Structure of Human JARID1B in Complex with CCT363901, PDB code: 5fpl
was solved by
V.Srikannathasan,
L.B.Yann-Vai,
R.Nowak,
C.Johansson,
C.Gileadi,
F.Vondelft,
C.H.Arrowsmith,
C.Bountra,
A.Edwards,
P.Brennan,
K.Huber,
U.Oppermann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5fpl:
The structure of Crystal Structure of Human JARID1B in Complex with CCT363901 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human JARID1B in Complex with CCT363901
(pdb code 5fpl). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human JARID1B in Complex with CCT363901, PDB code: 5fpl: Zinc binding site 1 out of 1 in 5fplGo back to Zinc Binding Sites List in 5fpl
Zinc binding site 1 out
of 1 in the Crystal Structure of Human JARID1B in Complex with CCT363901
Mono view Stereo pair view
Reference:
V.Bavetsias,
R.M.Lanigan,
G.F.Ruda,
B.Atrash,
M.G.Mclaughlin,
A.Tumber,
N.Y.Mok,
Y.Le Bihan,
S.Dempster,
K.J.Boxall,
F.Jeganathan,
S.B.Hatch,
P.Savitsky,
S.Velupillai,
T.Krojer,
K.S.England,
J.Sejberg,
C.Thai,
A.Donovan,
A.Pal,
G.Scozzafava,
J.M.Bennett,
A.Kawamura,
C.Johansson,
A.Szykowska,
C.Gileadi,
N.A.Burgess-Brown,
F.Von Delft,
U.Oppermann,
Z.Walters,
J.Shipley,
F.I.Raynaud,
S.M.Westaway,
R.K.Prinjha,
O.Fedorov,
R.Burke,
C.J.Schofield,
I.M.Westwood,
C.Bountra,
S.Muller,
R.L.M.Van Montfort,
P.E.Brennan,
J.Blagg.
8-Substituted Pyrido[3,4-D]Pyrimidin-4(3H)-One Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. J.Med.Chem. V. 59 1388 2016.
Page generated: Wed Dec 16 06:15:44 2020
ISSN: ISSN 0022-2623 PubMed: 26741168 DOI: 10.1021/ACS.JMEDCHEM.5B01635 |
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