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Zinc in PDB 5fp7: Crystal Structure of Human KDM4D in Complex with 3-4-Methylthiophen-2- Yl Methylaminopyridine-4-Carboxylic AcidProtein crystallography data
The structure of Crystal Structure of Human KDM4D in Complex with 3-4-Methylthiophen-2- Yl Methylaminopyridine-4-Carboxylic Acid, PDB code: 5fp7
was solved by
C.Chung,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5fp7:
The structure of Crystal Structure of Human KDM4D in Complex with 3-4-Methylthiophen-2- Yl Methylaminopyridine-4-Carboxylic Acid also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human KDM4D in Complex with 3-4-Methylthiophen-2- Yl Methylaminopyridine-4-Carboxylic Acid
(pdb code 5fp7). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human KDM4D in Complex with 3-4-Methylthiophen-2- Yl Methylaminopyridine-4-Carboxylic Acid, PDB code: 5fp7: Zinc binding site 1 out of 1 in 5fp7Go back to![]() ![]()
Zinc binding site 1 out
of 1 in the Crystal Structure of Human KDM4D in Complex with 3-4-Methylthiophen-2- Yl Methylaminopyridine-4-Carboxylic Acid
![]() Mono view ![]() Stereo pair view
Reference:
S.M.Westaway,
A.G.Preston,
M.D.Barker,
F.Brown,
J.A.Brown,
M.Campbell,
C.W.Chung,
G.Drewes,
R.Eagle,
N.Garton,
L.Gordon,
C.Haslam,
T.G.Hayhow,
P.G.Humphreys,
G.Joberty,
R.Katso,
L.Kruidenier,
M.Leveridge,
M.Pemberton,
I.Rioja,
G.A.Seal,
T.Shipley,
O.Singh,
C.J.Suckling,
J.Taylor,
P.Thomas,
D.M.Wilson,
K.Lee,
R.K.Prinjha.
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-D]Pyrimidin-4(3H)-One Derivatives. J. Med. Chem. V. 59 1370 2016.
Page generated: Wed Dec 16 06:15:33 2020
ISSN: ISSN 1520-4804 PubMed: 26771203 DOI: 10.1021/ACS.JMEDCHEM.5B01538 |
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