Zinc in PDB 5abs: Crystal Structure of the C-Terminal Coiled-Coil Domain of CIN85 in Space Group P321

The structure of Crystal Structure of the C-Terminal Coiled-Coil Domain of CIN85 in Space Group P321, PDB code: 5abs was solved by L.Wong, M.Habeck, C.Griesinger, S.Becker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.02 / 1.74
Space group	P 3 2 1
Cell size a, b, c (Å), α, β, γ (°)	40.968, 40.968, 90.036, 90.00, 90.00, 120.00
R / Rfree (%)	24.4 / 28.3

The binding sites of Zinc atom in the Crystal Structure of the C-Terminal Coiled-Coil Domain of CIN85 in Space Group P321 (pdb code 5abs). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of the C-Terminal Coiled-Coil Domain of CIN85 in Space Group P321, PDB code: 5abs:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Crystal Structure of the C-Terminal Coiled-Coil Domain of CIN85 in Space Group P321


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the C-Terminal Coiled-Coil Domain of CIN85 in Space Group P321 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:62.9 occ:1.00 OE2 A:GLU643 2.2 58.8 1.0 NZ A:LYS646 2.3 53.1 1.0 O A:HOH2012 2.6 63.2 1.0 OE1 A:GLU643 2.8 42.2 1.0 CD A:GLU643 2.9 47.7 1.0 CE A:LYS646 3.0 46.8 1.0 CG A:GLU643 4.3 41.1 1.0 CD A:LYS646 4.4 44.7 1.0 NH2 A:ARG650 4.7 60.5 1.0 CG1 A:ILE647 5.0 34.9 1.0

Zinc binding site 2 out of 4 in the Crystal Structure of the C-Terminal Coiled-Coil Domain of CIN85 in Space Group P321


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the C-Terminal Coiled-Coil Domain of CIN85 in Space Group P321 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1002 b:37.9 occ:1.00 OD1 A:ASP642 2.0 34.3 1.0 CG A:ASP642 2.8 38.5 1.0 OD2 A:ASP642 2.9 35.9 1.0 CD1 A:LEU638 3.9 44.4 1.0 NZ A:LYS645 4.0 32.2 1.0 CB A:ASP642 4.1 32.8 1.0 CD A:LYS645 4.5 31.6 1.0 CE A:LYS645 4.6 33.0 1.0 CA A:ASP642 4.6 29.7 1.0 CG A:LEU638 5.0 39.6 1.0 N A:ASP642 5.0 27.3 1.0

Zinc binding site 3 out of 4 in the Crystal Structure of the C-Terminal Coiled-Coil Domain of CIN85 in Space Group P321


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of the C-Terminal Coiled-Coil Domain of CIN85 in Space Group P321 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1003 b:41.8 occ:0.50 OE2 A:GLU624 2.0 37.5 1.0 OD2 A:ASP628 2.0 34.9 1.0 CG A:ASP628 2.8 33.8 1.0 CD A:GLU624 2.9 42.1 1.0 OD1 A:ASP628 3.0 37.1 1.0 CG A:GLU624 3.1 38.9 1.0 OE1 A:GLU624 4.0 40.8 1.0 CB A:ASP628 4.2 34.6 1.0 O A:GLU624 4.3 35.5 1.0 NZ A:LYS627 4.3 63.1 1.0 CB A:GLU624 4.6 39.7 1.0 C A:GLU624 4.8 38.0 1.0

Zinc binding site 4 out of 4 in the Crystal Structure of the C-Terminal Coiled-Coil Domain of CIN85 in Space Group P321


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of the C-Terminal Coiled-Coil Domain of CIN85 in Space Group P321 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1004 b:79.6 occ:0.50 OD1 A:ASP657 2.7 56.0 1.0 OD2 A:ASP657 2.8 60.6 1.0 CG A:ASP657 3.1 56.7 1.0 CE A:MSE653 4.0 68.1 0.5 SE A:MSE653 4.1 85.0 0.5 CB A:ASP657 4.6 48.4 1.0 CG A:MSE653 5.0 60.9 0.5

J.Kuhn, L.E.Wong, S.Pirkuliyeva, K.Schulz, C.Schwiegk, K.G.Funfgeld, S.Keppler, F.D.Batista, H.Urlaub, M.Habeck, S.Becker, C.Griesinger, J.Wienands. The Adaptor Protein CIN85 Assembles Intracellular Signaling Clusters For B Cell Activation. Sci.Signal. V. 9 RA66 2016.
ISSN: ESSN 1937-9145
PubMed: 27353366
DOI: 10.1126/SCISIGNAL.AAD6275