Zinc in PDB 4zd4: Catalytic Domain of SST2 F403W Mutant

The structure of Catalytic Domain of SST2 F403W Mutant, PDB code: 4zd4 was solved by A.N.Bueno, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.17 / 1.63
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	58.636, 73.697, 64.633, 90.00, 113.15, 90.00
R / Rfree (%)	18.4 / 20.9

The binding sites of Zinc atom in the Catalytic Domain of SST2 F403W Mutant (pdb code 4zd4). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Catalytic Domain of SST2 F403W Mutant, PDB code: 4zd4:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Catalytic Domain of SST2 F403W Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Catalytic Domain of SST2 F403W Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn507 b:17.5 occ:1.00 O A:HOH603 2.0 20.8 1.0 OD2 A:ASP354 2.0 15.1 1.0 NE2 A:HIS343 2.0 15.5 1.0 NE2 A:HIS341 2.0 13.8 1.0 CG A:ASP354 2.7 14.3 1.0 OD1 A:ASP354 2.7 17.1 1.0 CD2 A:HIS343 2.9 17.5 1.0 CE1 A:HIS341 3.0 18.1 1.0 CE1 A:HIS343 3.1 15.3 1.0 CD2 A:HIS341 3.1 16.0 1.0 OE2 A:GLU286 3.8 24.2 1.0 O A:HOH622 4.0 28.6 1.0 C1 A:EDO504 4.0 35.7 1.0 OG A:SER351 4.0 18.1 1.0 CG A:HIS343 4.1 16.8 1.0 ND1 A:HIS341 4.1 13.2 1.0 ND1 A:HIS343 4.1 18.6 1.0 CB A:ASP354 4.1 14.1 1.0 O1 A:EDO504 4.1 40.9 1.0 CG A:HIS341 4.2 13.9 1.0 CB A:SER351 4.4 18.6 1.0 O1 A:EDO501 4.4 23.2 1.0 N A:SER351 4.4 15.6 1.0 O A:PHE349 4.5 24.1 1.0 CD A:GLU286 4.6 19.1 1.0 OE1 A:GLU286 4.6 20.3 1.0 C1 A:EDO501 4.8 21.2 1.0 CG1 A:VAL372 4.8 15.9 1.0

Zinc binding site 2 out of 4 in the Catalytic Domain of SST2 F403W Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Catalytic Domain of SST2 F403W Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn508 b:22.3 occ:1.00 NE2 A:HIS406 1.9 20.7 1.0 NE2 A:HIS404 2.0 27.5 1.0 NE2 A:HIS356 2.0 19.2 1.0 SG A:CYS397 2.3 21.9 1.0 CE1 A:HIS406 2.9 25.5 1.0 CD2 A:HIS406 2.9 22.7 1.0 CD2 A:HIS404 3.0 27.2 1.0 CE1 A:HIS356 3.0 20.3 1.0 CE1 A:HIS404 3.0 27.9 1.0 CD2 A:HIS356 3.1 22.1 1.0 CB A:CYS397 3.2 22.1 1.0 O B:HOH615 3.8 32.6 1.0 ND1 A:HIS406 4.0 26.9 1.0 CG A:HIS406 4.0 25.6 1.0 CG A:HIS404 4.1 29.4 1.0 ND1 A:HIS356 4.1 21.2 1.0 ND1 A:HIS404 4.1 29.4 1.0 CG A:HIS356 4.2 19.4 1.0 OG A:SER352 4.3 29.0 1.0 CD1 A:ILE394 4.6 22.6 1.0 CA A:CYS397 4.6 21.8 1.0 NH2 B:ARG398 4.9 35.5 1.0 C A:CYS397 4.9 26.9 1.0

Zinc binding site 3 out of 4 in the Catalytic Domain of SST2 F403W Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Catalytic Domain of SST2 F403W Mutant within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn508 b:17.4 occ:1.00 O B:HOH608 1.9 23.9 1.0 OD2 B:ASP354 2.0 17.1 1.0 NE2 B:HIS343 2.0 14.8 1.0 NE2 B:HIS341 2.1 13.8 1.0 CG B:ASP354 2.7 16.6 1.0 OD1 B:ASP354 2.7 15.7 1.0 CD2 B:HIS343 2.9 18.7 1.0 CE1 B:HIS341 3.0 19.4 1.0 CE1 B:HIS343 3.1 15.6 1.0 CD2 B:HIS341 3.1 16.5 1.0 OE2 B:GLU286 3.9 20.6 1.0 OG B:SER351 3.9 20.0 1.0 O B:HOH611 4.0 30.6 1.0 CG B:HIS343 4.1 14.2 1.0 ND1 B:HIS343 4.1 17.1 1.0 C1 B:EDO503 4.1 32.0 1.0 CB B:ASP354 4.1 16.6 1.0 ND1 B:HIS341 4.1 13.4 1.0 CG B:HIS341 4.2 14.1 1.0 CB B:SER351 4.4 18.9 1.0 N B:SER351 4.4 15.7 1.0 OE1 B:GLU286 4.5 22.0 1.0 O B:PHE349 4.5 20.9 1.0 CD B:GLU286 4.5 17.3 1.0 CG1 B:VAL372 4.8 18.6 1.0

Zinc binding site 4 out of 4 in the Catalytic Domain of SST2 F403W Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Catalytic Domain of SST2 F403W Mutant within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn509 b:22.7 occ:1.00 NE2 B:HIS406 1.9 23.7 1.0 NE2 B:HIS356 2.0 21.1 1.0 NE2 B:HIS404 2.1 25.1 1.0 SG B:CYS397 2.3 22.1 1.0 CE1 B:HIS406 2.7 30.2 1.0 CD2 B:HIS406 3.0 20.7 1.0 CE1 B:HIS356 3.0 20.3 1.0 CE1 B:HIS404 3.0 26.2 1.0 CD2 B:HIS356 3.0 23.4 1.0 CD2 B:HIS404 3.0 31.7 1.0 CB B:CYS397 3.3 25.2 1.0 O A:HOH602 3.9 38.6 1.0 ND1 B:HIS406 3.9 30.1 1.0 CG B:HIS406 4.0 31.3 1.0 ND1 B:HIS356 4.1 21.4 1.0 ND1 B:HIS404 4.1 35.2 1.0 CG B:HIS356 4.2 19.2 1.0 CG B:HIS404 4.2 33.1 1.0 OG B:SER352 4.4 29.5 1.0 CD1 B:ILE394 4.6 21.4 1.0 CA B:CYS397 4.7 25.5 1.0 C B:CYS397 4.9 31.3 1.0 NH1 A:ARG398 4.9 41.1 1.0 O B:CYS397 5.0 32.1 1.0

A.N.Bueno, A.N.Bueno. N/A N/A.