Zinc in PDB 4z3u: Prv Nuclear Egress Complex

The structure of Prv Nuclear Egress Complex, PDB code: 4z3u was solved by J.M.Bigalke, E.E.Heldwein, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.91 / 2.71
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	125.456, 125.456, 109.235, 90.00, 90.00, 90.00
R / Rfree (%)	21.2 / 27.3

The structure of Prv Nuclear Egress Complex also contains other interesting chemical elements:

Chlorine	(Cl)	5 atoms
Sodium	(Na)	1 atom

The binding sites of Zinc atom in the Prv Nuclear Egress Complex (pdb code 4z3u). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Prv Nuclear Egress Complex, PDB code: 4z3u:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Prv Nuclear Egress Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Prv Nuclear Egress Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn301 b:67.4 occ:1.00 NE2 B:HIS188 2.4 73.5 1.0 SG B:CYS89 2.6 78.6 1.0 CE1 B:HIS188 2.6 74.8 1.0 SG B:CYS73 2.6 45.5 1.0 SG B:CYS92 2.6 58.5 1.0 CB B:CYS73 3.0 46.0 1.0 CB B:CYS89 3.2 40.2 1.0 CB B:CYS92 3.6 42.4 1.0 CD2 B:HIS188 3.8 60.6 1.0 ND1 B:HIS188 3.9 64.0 1.0 N B:CYS92 4.0 53.2 1.0 CA B:CYS92 4.3 63.1 1.0 CG B:HIS188 4.5 55.4 1.0 CA B:CYS73 4.5 38.8 1.0 CA B:CYS89 4.7 49.6 1.0 CB B:THR91 4.8 59.0 1.0 CA B:GLY86 4.9 47.4 1.0 O B:VAL189 5.0 56.1 1.0 C B:THR91 5.0 54.0 1.0

Zinc binding site 2 out of 2 in the Prv Nuclear Egress Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Prv Nuclear Egress Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn301 b:53.0 occ:1.00 NE2 D:HIS188 2.4 60.5 1.0 SG D:CYS73 2.6 47.0 1.0 CE1 D:HIS188 2.6 67.9 1.0 SG D:CYS92 2.6 66.2 1.0 SG D:CYS89 2.6 59.4 1.0 CB D:CYS73 2.8 46.7 1.0 CB D:CYS89 3.1 43.1 1.0 CD2 D:HIS188 3.8 64.2 1.0 CB D:CYS92 3.8 54.4 1.0 ND1 D:HIS188 3.9 70.4 1.0 N D:CYS92 4.1 67.2 1.0 CA D:CYS73 4.3 45.8 1.0 CA D:CYS92 4.4 61.8 1.0 CG D:HIS188 4.5 66.5 1.0 CA D:CYS89 4.6 42.0 1.0 CA D:GLY86 4.8 51.3 1.0 O D:VAL189 4.8 56.1 1.0 CB D:THR91 4.8 63.9 1.0 C D:CYS73 4.9 50.5 1.0

J.M.Bigalke, E.E.Heldwein. Structural Basis of Membrane Budding By the Nuclear Egress Complex of Herpesviruses. Embo J. V. 34 2921 2015.
ISSN: ESSN 1460-2075
PubMed: 26511020
DOI: 10.15252/EMBJ.201592359