Atomistry » Zinc » PDB 4y8a-4ylo » 4yf6
Atomistry »
  Zinc »
    PDB 4y8a-4ylo »
      4yf6 »

Zinc in PDB 4yf6: Crystal Structure of Oxidised RV1284

Enzymatic activity of Crystal Structure of Oxidised RV1284

All present enzymatic activity of Crystal Structure of Oxidised RV1284:
4.2.1.1;

Protein crystallography data

The structure of Crystal Structure of Oxidised RV1284, PDB code: 4yf6 was solved by A.Hofmann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 24.39 / 3.00
Space group F 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 101.068, 153.947, 157.174, 90.00, 90.00, 90.00
R / Rfree (%) 16.7 / 26

Other elements in 4yf6:

The structure of Crystal Structure of Oxidised RV1284 also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms
Chlorine (Cl) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Oxidised RV1284 (pdb code 4yf6). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of Oxidised RV1284, PDB code: 4yf6:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in 4yf6

Go back to Zinc Binding Sites List in 4yf6
Zinc binding site 1 out of 4 in the Crystal Structure of Oxidised RV1284


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Oxidised RV1284 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn200

b:37.0
occ:0.59
NE2 A:HIS88 2.2 40.4 1.0
SG A:CYS91 2.3 37.8 1.0
SG A:CYS35 2.4 2.4 0.7
CD2 A:HIS88 3.1 40.4 1.0
CE1 A:HIS88 3.2 40.4 1.0
CB A:CYS35 3.6 2.4 0.7
CB A:CYS35 3.7 2.4 0.3
CB A:CYS91 3.7 37.8 1.0
CB A:ASP37 3.7 10.4 1.0
OD2 A:ASP37 3.7 10.4 1.0
N A:GLY92 3.8 69.0 1.0
CA A:CYS91 4.0 71.4 1.0
CG A:ASP37 4.2 10.4 1.0
SG A:CYS35 4.3 2.4 0.3
CG A:HIS88 4.3 40.4 1.0
ND1 A:HIS88 4.3 40.4 1.0
CA A:GLY60 4.3 5.5 1.0
N A:GLY60 4.3 5.5 1.0
C A:CYS91 4.4 71.4 1.0
N A:ASP37 4.5 20.7 1.0
CA A:ASP37 4.6 20.7 1.0
SG A:CYS61 4.8 5.4 0.3
CA A:GLY92 4.8 69.0 1.0
C A:GLY60 5.0 5.5 1.0

Zinc binding site 2 out of 4 in 4yf6

Go back to Zinc Binding Sites List in 4yf6
Zinc binding site 2 out of 4 in the Crystal Structure of Oxidised RV1284


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Oxidised RV1284 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn200

b:37.0
occ:0.55
SG B:CYS91 2.2 52.1 1.0
SG B:CYS35 2.3 10.8 0.6
NE2 B:HIS88 2.4 25.9 1.0
CE1 B:HIS88 3.4 25.9 1.0
CD2 B:HIS88 3.4 25.9 1.0
CB B:ASP37 3.6 17.6 1.0
OD2 B:ASP37 3.6 17.6 1.0
CB B:CYS35 3.7 10.8 0.6
CB B:CYS35 3.7 10.8 0.4
CB B:CYS91 3.8 52.1 1.0
CG B:ASP37 4.1 17.6 1.0
N B:GLY60 4.1 37.1 1.0
N B:GLY92 4.2 64.4 1.0
N B:ASP37 4.2 3.9 1.0
CA B:CYS91 4.2 92.6 1.0
CA B:GLY60 4.2 37.1 1.0
CA B:ASP37 4.3 3.9 1.0
SG B:CYS35 4.5 10.8 0.4
ND1 B:HIS88 4.5 25.9 1.0
CG B:HIS88 4.6 25.9 1.0
C B:CYS91 4.7 92.6 1.0
N B:MET36 4.9 14.5 1.0

Zinc binding site 3 out of 4 in 4yf6

Go back to Zinc Binding Sites List in 4yf6
Zinc binding site 3 out of 4 in the Crystal Structure of Oxidised RV1284


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of Oxidised RV1284 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn200

b:37.0
occ:0.60
NE2 C:HIS88 2.1 44.3 1.0
SG C:CYS91 2.5 51.0 1.0
SG C:CYS35 2.5 5.4 0.6
CE1 C:HIS88 2.9 44.3 1.0
CD2 C:HIS88 3.2 44.3 1.0
CB C:CYS35 3.4 5.4 0.6
CB C:CYS35 3.5 5.4 0.4
CB C:ASP37 3.7 38.8 1.0
O C:HOH301 3.9 32.4 1.0
OD2 C:ASP37 4.0 38.8 1.0
CB C:CYS91 4.0 51.0 1.0
ND1 C:HIS88 4.1 44.3 1.0
CA C:GLY60 4.1 19.6 1.0
N C:GLY60 4.1 19.6 1.0
CG C:HIS88 4.2 44.3 1.0
SG C:CYS35 4.3 5.4 0.4
N C:GLY92 4.3 79.2 1.0
CG C:ASP37 4.3 38.8 1.0
CA C:CYS91 4.5 97.4 1.0
N C:ASP37 4.5 18.1 1.0
CA C:ASP37 4.5 18.1 1.0
SG C:CYS61 4.5 11.2 0.4
CG C:MET93 4.8 77.5 1.0
C C:GLY60 4.8 19.6 1.0
CA C:CYS35 4.8 23.8 0.4
CA C:CYS35 4.9 23.8 0.6
C C:CYS91 4.9 97.4 1.0

Zinc binding site 4 out of 4 in 4yf6

Go back to Zinc Binding Sites List in 4yf6
Zinc binding site 4 out of 4 in the Crystal Structure of Oxidised RV1284


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of Oxidised RV1284 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn200

b:37.0
occ:0.58
NE2 D:HIS88 2.2 36.4 1.0
SG D:CYS35 2.4 3.4 0.5
SG D:CYS91 2.6 58.7 1.0
CE1 D:HIS88 2.8 36.4 1.0
CD2 D:HIS88 3.4 36.4 1.0
N D:GLY92 3.5 82.9 1.0
CB D:CYS35 3.9 3.4 0.5
OD2 D:ASP37 3.9 32.8 1.0
CB D:CYS35 4.0 3.4 0.5
CB D:ASP37 4.0 32.8 1.0
CB D:CYS91 4.0 58.7 1.0
ND1 D:HIS88 4.1 36.4 1.0
N D:GLY60 4.1 18.7 1.0
CA D:GLY60 4.1 18.7 1.0
CA D:CYS91 4.2 66.4 1.0
CA D:GLY92 4.3 82.9 1.0
CG D:HIS88 4.3 36.4 1.0
C D:CYS91 4.4 66.4 1.0
CG D:ASP37 4.4 32.8 1.0
N D:ASP37 4.7 17.0 1.0
CA D:ASP37 4.7 17.0 1.0
SG D:CYS35 4.8 3.4 0.5
N D:MET93 5.0 52.0 1.0
CG D:MET93 5.0 37.3 1.0

Reference:

L.Nienaber, E.Cave-Freeman, M.Cross, L.Mason, U.M.Bailey, P.Amani, R.Davis, P.Taylor, A.Hofmann. Chemical Probing Suggests Redox-Regulation of the Carbonic Anhydrase Activity of Mycobacterial RV1284. Febs J. 2015.
ISSN: ISSN 1742-464X
PubMed: 25929542
DOI: 10.1111/FEBS.13313
Page generated: Wed Dec 16 05:56:37 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy