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Atomistry » Zinc » PDB 4x3p-4xfw » 4xct | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 4x3p-4xfw » 4xct » |
Zinc in PDB 4xct: Crystal Structure of A Hydroxamate Based Inhibitor ARP101 (EN73) in Complex with the Mmp-9 Catalytic Domain.Enzymatic activity of Crystal Structure of A Hydroxamate Based Inhibitor ARP101 (EN73) in Complex with the Mmp-9 Catalytic Domain.
All present enzymatic activity of Crystal Structure of A Hydroxamate Based Inhibitor ARP101 (EN73) in Complex with the Mmp-9 Catalytic Domain.:
3.4.24.35; Protein crystallography data
The structure of Crystal Structure of A Hydroxamate Based Inhibitor ARP101 (EN73) in Complex with the Mmp-9 Catalytic Domain., PDB code: 4xct
was solved by
E.A.Stura,
L.Tepshi,
E.Nuti,
V.Dive,
E.Cassar-Lajeunesse,
L.Vera,
A.Rossello,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4xct:
The structure of Crystal Structure of A Hydroxamate Based Inhibitor ARP101 (EN73) in Complex with the Mmp-9 Catalytic Domain. also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of A Hydroxamate Based Inhibitor ARP101 (EN73) in Complex with the Mmp-9 Catalytic Domain.
(pdb code 4xct). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of A Hydroxamate Based Inhibitor ARP101 (EN73) in Complex with the Mmp-9 Catalytic Domain., PDB code: 4xct: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 4xctGo back to Zinc Binding Sites List in 4xct
Zinc binding site 1 out
of 2 in the Crystal Structure of A Hydroxamate Based Inhibitor ARP101 (EN73) in Complex with the Mmp-9 Catalytic Domain.
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 4xctGo back to Zinc Binding Sites List in 4xct
Zinc binding site 2 out
of 2 in the Crystal Structure of A Hydroxamate Based Inhibitor ARP101 (EN73) in Complex with the Mmp-9 Catalytic Domain.
Mono view Stereo pair view
Reference:
E.Nuti,
C.Camodeca,
A.R.Cantelmo,
T.Tuccinardi,
L.Vera,
L.Tepshi,
E.Orlandini,
S.Nencetti,
E.A.Stura,
A.Albini,
A.Martinelli,
V.Dive,
A.Rossello.
N-O-Isopropyl Sulphonamido-Based Hydroxamates As Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity. Journal of Medicinalchemistry.
Page generated: Sun Oct 27 10:27:15 2024
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