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Atomistry » Zinc » PDB 4ufy-4upt » 4uh8 » |
Zinc in PDB 4uh8: Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N1-(5-(2-(6-Amino-4-Methylpyridin-2- Yl)Ethyl)Pyridin-3-Yl)-N1,N2-Dimethylethane-1,2-DiamineEnzymatic activity of Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N1-(5-(2-(6-Amino-4-Methylpyridin-2- Yl)Ethyl)Pyridin-3-Yl)-N1,N2-Dimethylethane-1,2-Diamine
All present enzymatic activity of Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N1-(5-(2-(6-Amino-4-Methylpyridin-2- Yl)Ethyl)Pyridin-3-Yl)-N1,N2-Dimethylethane-1,2-Diamine:
1.14.13.39; Protein crystallography data
The structure of Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N1-(5-(2-(6-Amino-4-Methylpyridin-2- Yl)Ethyl)Pyridin-3-Yl)-N1,N2-Dimethylethane-1,2-Diamine, PDB code: 4uh8
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4uh8:
The structure of Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N1-(5-(2-(6-Amino-4-Methylpyridin-2- Yl)Ethyl)Pyridin-3-Yl)-N1,N2-Dimethylethane-1,2-Diamine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N1-(5-(2-(6-Amino-4-Methylpyridin-2- Yl)Ethyl)Pyridin-3-Yl)-N1,N2-Dimethylethane-1,2-Diamine
(pdb code 4uh8). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N1-(5-(2-(6-Amino-4-Methylpyridin-2- Yl)Ethyl)Pyridin-3-Yl)-N1,N2-Dimethylethane-1,2-Diamine, PDB code: 4uh8: Zinc binding site 1 out of 1 in 4uh8Go back to Zinc Binding Sites List in 4uh8
Zinc binding site 1 out
of 1 in the Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with N1-(5-(2-(6-Amino-4-Methylpyridin-2- Yl)Ethyl)Pyridin-3-Yl)-N1,N2-Dimethylethane-1,2-Diamine
Mono view Stereo pair view
Reference:
S.Kang,
H.Li,
W.Tang,
P.Martasek,
L.J.Roman,
T.L.Poulos,
R.B.Silverman.
2-Aminopyridines with A Truncated Side Chain to Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity. J.Med.Chem. V. 58 5548 2015.
Page generated: Sun Oct 27 09:09:32 2024
ISSN: ISSN 0022-2623 PubMed: 26120733 DOI: 10.1021/ACS.JMEDCHEM.5B00573 |
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