Atomistry » Zinc » PDB 4rvd-4toi » 4tli
Atomistry »
  Zinc »
    PDB 4rvd-4toi »
      4tli »

Zinc in PDB 4tli: Thermolysin (25% Isopropanol Soaked Crystals)

Enzymatic activity of Thermolysin (25% Isopropanol Soaked Crystals)

All present enzymatic activity of Thermolysin (25% Isopropanol Soaked Crystals):
3.4.24.27;

Protein crystallography data

The structure of Thermolysin (25% Isopropanol Soaked Crystals), PDB code: 4tli was solved by A.C.English, S.H.Done, C.R.Groom, R.E.Hubbard, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 1.95
Space group P 61 2 2
Cell size a, b, c (Å), α, β, γ (°) 94.140, 94.140, 130.800, 90.00, 90.00, 120.00
R / Rfree (%) 16.4 / 20.6

Other elements in 4tli:

The structure of Thermolysin (25% Isopropanol Soaked Crystals) also contains other interesting chemical elements:

Calcium (Ca) 4 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Thermolysin (25% Isopropanol Soaked Crystals) (pdb code 4tli). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Thermolysin (25% Isopropanol Soaked Crystals), PDB code: 4tli:

Zinc binding site 1 out of 1 in 4tli

Go back to Zinc Binding Sites List in 4tli
Zinc binding site 1 out of 1 in the Thermolysin (25% Isopropanol Soaked Crystals)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Thermolysin (25% Isopropanol Soaked Crystals) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn401

b:23.9
occ:1.00
O A:HOH1002 1.8 33.1 1.0
NE2 A:HIS146 2.0 21.0 1.0
NE2 A:HIS142 2.1 22.4 1.0
OE2 A:GLU166 2.2 28.6 1.0
OE1 A:GLU166 2.3 30.8 1.0
CD A:GLU166 2.8 28.6 1.0
CE1 A:HIS146 3.0 21.7 1.0
CE1 A:HIS142 3.0 19.0 1.0
CD2 A:HIS146 3.1 20.0 1.0
CD2 A:HIS142 3.1 20.4 1.0
O A:HOH1001 3.2 51.6 1.0
OE2 A:GLU143 3.7 25.3 1.0
OH A:TYR157 4.0 34.1 0.4
ND1 A:HIS146 4.1 22.5 1.0
CG A:HIS146 4.2 19.5 1.0
ND1 A:HIS142 4.2 19.5 1.0
O A:HOH1067 4.2 43.7 1.0
CG A:HIS142 4.2 18.7 1.0
CG A:GLU166 4.3 20.0 1.0
CB A:SER169 4.3 18.4 1.0
CD A:GLU143 4.5 24.2 1.0
O2 A:IPA2002 4.5 58.8 1.0
OE1 A:GLU143 4.5 22.4 1.0
CA A:GLU166 4.6 20.5 1.0
OG A:SER169 4.6 19.4 1.0
O A:HOH1087 4.7 47.9 1.0
CB A:GLU166 4.8 21.1 1.0
NE2 A:HIS231 4.9 27.8 1.0

Reference:

A.C.English, S.H.Done, L.S.Caves, C.R.Groom, R.E.Hubbard. Locating Interaction Sites on Proteins: the Crystal Structure of Thermolysin Soaked in 2% to 100% Isopropanol. Proteins V. 37 628 1999.
ISSN: ISSN 0887-3585
PubMed: 10651278
DOI: 10.1002/(SICI)1097-0134(19991201)37:4<628::AID-PROT13>3.3.CO;2-7
Page generated: Wed Dec 16 05:46:56 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy