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Atomistry » Zinc » PDB 4pog-4q1l » 4puk » |
Zinc in PDB 4puk: Trna-Guanine Transglycosylase (Tgt) in Complex with 6-Amino-2- (Methylamino)-1H,7H,8H-Imidazo[4,5-G]Quinazolin-8-OneEnzymatic activity of Trna-Guanine Transglycosylase (Tgt) in Complex with 6-Amino-2- (Methylamino)-1H,7H,8H-Imidazo[4,5-G]Quinazolin-8-One
All present enzymatic activity of Trna-Guanine Transglycosylase (Tgt) in Complex with 6-Amino-2- (Methylamino)-1H,7H,8H-Imidazo[4,5-G]Quinazolin-8-One:
2.4.2.29; Protein crystallography data
The structure of Trna-Guanine Transglycosylase (Tgt) in Complex with 6-Amino-2- (Methylamino)-1H,7H,8H-Imidazo[4,5-G]Quinazolin-8-One, PDB code: 4puk
was solved by
M.Neeb,
A.Heine,
G.Klebe,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Trna-Guanine Transglycosylase (Tgt) in Complex with 6-Amino-2- (Methylamino)-1H,7H,8H-Imidazo[4,5-G]Quinazolin-8-One
(pdb code 4puk). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Trna-Guanine Transglycosylase (Tgt) in Complex with 6-Amino-2- (Methylamino)-1H,7H,8H-Imidazo[4,5-G]Quinazolin-8-One, PDB code: 4puk: Zinc binding site 1 out of 1 in 4pukGo back to Zinc Binding Sites List in 4puk
Zinc binding site 1 out
of 1 in the Trna-Guanine Transglycosylase (Tgt) in Complex with 6-Amino-2- (Methylamino)-1H,7H,8H-Imidazo[4,5-G]Quinazolin-8-One
Mono view Stereo pair view
Reference:
M.Neeb,
P.Czodrowski,
A.Heine,
L.J.Barandun,
C.Hohn,
F.Diederich,
G.Klebe.
Chasing Protons: How Isothermal Titration Calorimetry, Mutagenesis, and Pka Calculations Trace the Locus of Charge in Ligand Binding to A Trna-Binding Enzyme. J.Med.Chem. V. 57 5554 2014.
Page generated: Sun Oct 27 06:05:13 2024
ISSN: ISSN 0022-2623 PubMed: 24955548 DOI: 10.1021/JM500401X |
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