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Zinc in PDB 4oiq: Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077 and Rifampicin
Enzymatic activity of Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077 and Rifampicin
All present enzymatic activity of Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077 and Rifampicin:
2.7.7.6;
2.7.7.6;
Protein crystallography data
The structure of Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077 and Rifampicin, PDB code: 4oiq
was solved by
Y.Zhang,
R.H.Ebright,
E.Arnold,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 48.68 / 3.62 |
| Space group | C 1 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 184.840, 104.183, 295.319, 90.00, 98.52, 90.00 |
| R / Rfree (%) | 19.9 / 24.8 |
Other elements in 4oiq:
The structure of Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077 and Rifampicin also contains other interesting chemical elements:
| Magnesium | (Mg) | 4 atoms |
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077 and Rifampicin
(pdb code 4oiq). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077 and Rifampicin, PDB code: 4oiq:
Jump to Zinc binding site number: 1; 2;
In total 2 binding sites of Zinc where determined in the Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077 and Rifampicin, PDB code: 4oiq:
Jump to Zinc binding site number: 1; 2;
Zinc binding site 1 out of 2 in 4oiq
Go back to
Zinc Binding Sites List in 4oiq
Zinc binding site 1 out
of 2 in the Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077 and Rifampicin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077 and Rifampicin within 5.0Å range:
|
Zinc binding site 2 out of 2 in 4oiq
Go back to
Zinc Binding Sites List in 4oiq
Zinc binding site 2 out
of 2 in the Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077 and Rifampicin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Crystal Structure of Thermus Thermophilus Transcription Initiation Complex Soaked with GE23077 and Rifampicin within 5.0Å range:
|
Reference:
Y.Zhang,
D.Degen,
M.X.Ho,
E.Sineva,
K.Y.Ebright,
Y.W.Ebright,
V.Mekler,
H.Vahedian-Movahed,
Y.Feng,
R.Yin,
S.Tuske,
H.Irschik,
R.Jansen,
S.Maffioli,
S.Donadio,
E.Arnold,
R.H.Ebright.
GE23077 Binds to the Rna Polymerase 'I' and 'I+1' Sites and Prevents the Binding of Initiating Nucleotides. Elife V. 3 02450 2014.
ISSN: ESSN 2050-084X
PubMed: 24755292
Page generated: Sun Oct 27 03:45:48 2024
ISSN: ESSN 2050-084X
PubMed: 24755292
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