Zinc in PDB 4nzg: Crystal Structure of the N-Terminal Domain of Moloney Murine Leukemia Virus Integrase, Northeast Structural Genomics Consortium Target OR3

The structure of Crystal Structure of the N-Terminal Domain of Moloney Murine Leukemia Virus Integrase, Northeast Structural Genomics Consortium Target OR3, PDB code: 4nzg was solved by R.Guan, M.Jiang, H.Janjua, M.Maglaqui, L.Zhao, R.Xiao, T.B.Acton, J.K.Everett, M.Roth, G.T.Montelione, Northeast Structural Genomicsconsortium (Nesg), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.07 / 2.15
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	44.659, 38.440, 135.275, 90.00, 91.70, 90.00
R / Rfree (%)	23.4 / 26.5

The binding sites of Zinc atom in the Crystal Structure of the N-Terminal Domain of Moloney Murine Leukemia Virus Integrase, Northeast Structural Genomics Consortium Target OR3 (pdb code 4nzg). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of the N-Terminal Domain of Moloney Murine Leukemia Virus Integrase, Northeast Structural Genomics Consortium Target OR3, PDB code: 4nzg:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Crystal Structure of the N-Terminal Domain of Moloney Murine Leukemia Virus Integrase, Northeast Structural Genomics Consortium Target OR3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the N-Terminal Domain of Moloney Murine Leukemia Virus Integrase, Northeast Structural Genomics Consortium Target OR3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:45.0 occ:1.00 ND1 A:HIS62 2.0 38.3 1.0 NE2 A:HIS58 2.1 51.8 1.0 SG A:CYS98 2.2 42.6 1.0 SG A:CYS95 2.3 45.5 1.0 CE1 A:HIS62 2.9 38.4 1.0 CD2 A:HIS58 3.0 50.6 1.0 CE1 A:HIS58 3.0 50.4 1.0 CG A:HIS62 3.1 40.2 1.0 CB A:CYS95 3.1 41.6 1.0 CB A:CYS98 3.4 50.4 1.0 CB A:HIS62 3.5 41.7 1.0 N A:CYS98 3.8 44.6 1.0 CA A:HIS62 3.9 44.4 1.0 CG A:HIS58 4.1 52.0 1.0 ND1 A:HIS58 4.1 51.8 1.0 NE2 A:HIS62 4.1 40.4 1.0 CA A:CYS98 4.1 45.8 1.0 CD2 A:HIS62 4.2 34.8 1.0 CA A:CYS95 4.6 41.9 1.0 C A:HIS62 4.6 41.3 1.0 O A:HIS62 4.7 45.6 1.0 O A:HIS58 4.7 43.2 1.0 CB A:ALA97 4.8 44.6 1.0 C A:ALA97 4.9 46.0 1.0 C A:CYS95 5.0 48.2 1.0

Zinc binding site 2 out of 4 in the Crystal Structure of the N-Terminal Domain of Moloney Murine Leukemia Virus Integrase, Northeast Structural Genomics Consortium Target OR3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the N-Terminal Domain of Moloney Murine Leukemia Virus Integrase, Northeast Structural Genomics Consortium Target OR3 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:41.9 occ:1.00 ND1 B:HIS62 2.0 37.8 1.0 NE2 B:HIS58 2.1 51.6 1.0 SG B:CYS98 2.3 42.1 1.0 SG B:CYS95 2.3 39.5 1.0 CD2 B:HIS58 2.9 41.0 1.0 CE1 B:HIS62 2.9 43.5 1.0 CE1 B:HIS58 3.1 49.2 1.0 CG B:HIS62 3.1 38.9 1.0 CB B:CYS95 3.3 37.3 1.0 CB B:CYS98 3.3 40.4 1.0 CB B:HIS62 3.5 43.2 1.0 N B:CYS98 3.7 42.1 1.0 CA B:HIS62 3.9 44.2 1.0 CG B:HIS58 4.1 47.8 1.0 CA B:CYS98 4.1 40.0 1.0 NE2 B:HIS62 4.1 42.8 1.0 ND1 B:HIS58 4.1 50.9 1.0 CD2 B:HIS62 4.2 38.3 1.0 CB B:ALA97 4.6 34.1 1.0 C B:HIS62 4.6 49.2 1.0 CA B:CYS95 4.7 39.9 1.0 O B:HIS62 4.7 53.1 1.0 O B:HIS58 4.7 41.7 1.0 C B:ALA97 4.7 39.9 1.0 N B:HIS62 5.0 38.4 1.0

Zinc binding site 3 out of 4 in the Crystal Structure of the N-Terminal Domain of Moloney Murine Leukemia Virus Integrase, Northeast Structural Genomics Consortium Target OR3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of the N-Terminal Domain of Moloney Murine Leukemia Virus Integrase, Northeast Structural Genomics Consortium Target OR3 within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn201 b:46.4 occ:1.00 CE1 C:HIS58 1.8 57.3 1.0 ND1 C:HIS62 2.0 37.5 1.0 NE2 C:HIS58 2.1 52.5 1.0 SG C:CYS98 2.2 46.9 1.0 SG C:CYS95 2.3 44.1 1.0 CE1 C:HIS62 2.9 42.4 1.0 ND1 C:HIS58 3.0 54.0 1.0 CG C:HIS62 3.1 40.0 1.0 CB C:CYS95 3.3 48.7 1.0 CB C:CYS98 3.3 50.0 1.0 CD2 C:HIS58 3.4 47.6 1.0 CB C:HIS62 3.5 44.3 1.0 CA C:HIS62 3.8 48.4 1.0 N C:CYS98 3.8 47.1 1.0 CG C:HIS58 3.8 50.9 1.0 NE2 C:HIS62 4.1 41.2 1.0 CA C:CYS98 4.1 49.0 1.0 CD2 C:HIS62 4.2 37.1 1.0 C C:HIS62 4.5 52.9 1.0 O C:HIS62 4.6 53.9 1.0 CA C:CYS95 4.7 52.0 1.0 CB C:ALA97 4.7 49.8 1.0 O C:HIS58 4.7 51.5 1.0 C C:ALA97 4.9 49.1 1.0 N C:HIS62 4.9 46.4 1.0

Zinc binding site 4 out of 4 in the Crystal Structure of the N-Terminal Domain of Moloney Murine Leukemia Virus Integrase, Northeast Structural Genomics Consortium Target OR3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of the N-Terminal Domain of Moloney Murine Leukemia Virus Integrase, Northeast Structural Genomics Consortium Target OR3 within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn201 b:48.7 occ:1.00 ND1 D:HIS62 2.0 39.8 1.0 NE2 D:HIS58 2.0 48.1 1.0 SG D:CYS95 2.3 48.3 1.0 SG D:CYS98 2.3 48.8 1.0 CD2 D:HIS58 2.9 45.7 1.0 CE1 D:HIS62 2.9 48.5 1.0 CE1 D:HIS58 3.1 53.7 1.0 CG D:HIS62 3.1 43.2 1.0 CB D:CYS95 3.2 53.3 1.0 CB D:CYS98 3.4 46.2 1.0 CB D:HIS62 3.5 47.4 1.0 N D:CYS98 3.8 52.7 1.0 CA D:HIS62 3.8 51.4 1.0 CG D:HIS58 4.0 51.2 1.0 NE2 D:HIS62 4.1 52.0 1.0 ND1 D:HIS58 4.1 52.1 1.0 CA D:CYS98 4.1 50.7 1.0 CD2 D:HIS62 4.2 45.1 1.0 C D:HIS62 4.6 52.3 1.0 CB D:ALA97 4.6 50.9 1.0 CA D:CYS95 4.6 53.3 1.0 O D:HIS62 4.7 61.4 1.0 O D:HIS58 4.7 53.3 1.0 C D:ALA97 4.8 50.8 1.0 N D:HIS62 5.0 52.0 1.0

R.Guan, M.Jiang, H.Janjua, M.Maglaqui, L.Zhao, R.Xiao, T.B.Acton, J.K.Everett, M.Roth, G.T.Montelione. Northeast Structural Genomics Consortium Target OR3 To Be Published.