Zinc in PDB 4nl4: Pria Helicase Bound to Adp

The structure of Pria Helicase Bound to Adp, PDB code: 4nl4 was solved by B.Bhattacharyya, N.P.George, J.L.Keck, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.14 / 2.65
Space group	P 32
Cell size a, b, c (Å), α, β, γ (°)	85.433, 85.433, 111.682, 90.00, 90.00, 120.00
R / Rfree (%)	21.8 / 25.4

The binding sites of Zinc atom in the Pria Helicase Bound to Adp (pdb code 4nl4). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Pria Helicase Bound to Adp, PDB code: 4nl4:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Pria Helicase Bound to Adp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Pria Helicase Bound to Adp within 5.0Å range: probe atom residue distance (Å) B Occ H:Zn802 b:93.2 occ:1.00 SG H:CYS444 2.3 65.1 1.0 SG H:CYS465 2.3 78.2 1.0 SG H:CYS462 2.3 60.4 1.0 SG H:CYS447 2.4 64.4 1.0 CB H:CYS444 3.2 60.4 1.0 CB H:CYS465 3.3 73.8 1.0 CB H:CYS462 3.4 60.1 1.0 CB H:CYS447 3.7 65.1 1.0 N H:CYS465 3.8 71.0 1.0 N H:CYS447 3.9 64.6 1.0 CA H:CYS465 4.0 71.1 1.0 O H:CYS447 4.1 69.8 1.0 CA H:CYS447 4.3 65.8 1.0 OG H:SER467 4.3 75.0 1.0 C H:CYS465 4.4 70.0 1.0 C H:CYS447 4.6 68.2 1.0 CB H:ARG446 4.6 61.8 1.0 CA H:CYS444 4.7 54.8 1.0 CB H:SER449 4.7 55.3 1.0 O H:CYS465 4.8 69.3 1.0 C H:HIS464 4.8 70.7 1.0 CA H:CYS462 4.8 57.5 1.0 CB H:SER467 5.0 72.8 1.0 C H:ARG446 5.0 63.5 1.0

Zinc binding site 2 out of 2 in the Pria Helicase Bound to Adp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Pria Helicase Bound to Adp within 5.0Å range: probe atom residue distance (Å) B Occ H:Zn803 b:50.2 occ:1.00 SG H:CYS438 2.3 42.7 1.0 SG H:CYS478 2.3 37.0 1.0 SG H:CYS475 2.3 40.3 1.0 SG H:CYS435 2.3 43.1 1.0 CB H:CYS435 3.1 40.7 1.0 CB H:CYS475 3.2 41.1 1.0 CB H:CYS438 3.3 40.5 1.0 CB H:CYS478 3.3 34.4 1.0 N H:CYS478 3.7 31.2 1.0 N H:CYS438 3.8 36.9 1.0 CA H:CYS478 4.0 32.2 1.0 CA H:CYS438 4.1 37.8 1.0 CB H:SER480 4.4 34.7 1.0 CB H:TRP440 4.5 35.6 1.0 CA H:CYS435 4.6 39.0 1.0 C H:CYS478 4.6 32.4 1.0 CB H:SER477 4.6 31.6 1.0 CA H:CYS475 4.6 39.5 1.0 C H:SER477 4.7 31.7 1.0 N H:GLY479 4.7 33.8 1.0 C H:CYS438 4.8 37.4 1.0 N H:SER480 4.8 35.2 1.0 N H:GLY439 4.9 38.0 1.0 C H:ASP437 4.9 36.4 1.0 CB H:ASP437 4.9 37.5 1.0 N H:TRP440 5.0 37.6 1.0

B.Bhattacharyya, N.P.George, T.M.Thurmes, R.Zhou, N.Jani, S.R.Wessel, S.J.Sandler, T.Ha, J.L.Keck. Structural Mechanisms of Pria-Mediated Dna Replication Restart. Proc.Natl.Acad.Sci.Usa V. 111 1373 2014.
ISSN: ISSN 0027-8424
PubMed: 24379377
DOI: 10.1073/PNAS.1318001111