Zinc in PDB 4mt2: Comparison of the uc(Nmr) Solution Structure and the X-Ray Crystal Structure of Rat Metallothionein-2

The structure of Comparison of the uc(Nmr) Solution Structure and the X-Ray Crystal Structure of Rat Metallothionein-2, PDB code: 4mt2 was solved by A.H.Robbins, C.D.Stout, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	5.00 / 2.00
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	30.900, 30.900, 120.400, 90.00, 90.00, 90.00
R / Rfree (%)	19.7 / n/a

The structure of Comparison of the uc(Nmr) Solution Structure and the X-Ray Crystal Structure of Rat Metallothionein-2 also contains other interesting chemical elements:

Cadmium	(Cd)	5 atoms
Sodium	(Na)	1 atom

The binding sites of Zinc atom in the Comparison of the uc(Nmr) Solution Structure and the X-Ray Crystal Structure of Rat Metallothionein-2 (pdb code 4mt2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Comparison of the uc(Nmr) Solution Structure and the X-Ray Crystal Structure of Rat Metallothionein-2, PDB code: 4mt2:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Comparison of the uc(Nmr) Solution Structure and the X-Ray Crystal Structure of Rat Metallothionein-2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Comparison of the uc(Nmr) Solution Structure and the X-Ray Crystal Structure of Rat Metallothionein-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn67 b:18.6 occ:1.00 SG A:CYS19 2.3 20.3 1.0 SG A:CYS29 2.4 19.2 1.0 SG A:CYS24 2.4 20.9 1.0 SG A:CYS15 2.5 21.8 1.0 CB A:CYS29 3.2 20.5 1.0 CB A:CYS19 3.4 21.4 1.0 CB A:CYS24 3.4 19.9 1.0 CB A:CYS15 3.6 21.2 1.0 CD A:CD66 3.9 21.9 1.0 ZN A:ZN68 3.9 22.6 1.0 N A:GLY17 4.3 23.1 1.0 N A:CYS19 4.6 22.8 1.0 SG A:CYS7 4.6 22.5 1.0 CA A:CYS19 4.6 22.3 1.0 CA A:CYS29 4.6 21.0 1.0 CB A:CYS26 4.7 20.8 1.0 C A:CYS15 4.8 22.0 1.0 CA A:CYS15 4.8 21.9 1.0 N A:ALA16 4.8 22.1 1.0 O A:HOH71 4.8 19.3 1.0 CA A:GLY17 4.8 24.2 1.0 CA A:CYS24 4.8 19.6 1.0 SG A:CYS21 4.9 22.5 1.0 CB A:CYS21 5.0 22.6 1.0 SG A:CYS26 5.0 23.0 1.0

Zinc binding site 2 out of 2 in the Comparison of the uc(Nmr) Solution Structure and the X-Ray Crystal Structure of Rat Metallothionein-2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Comparison of the uc(Nmr) Solution Structure and the X-Ray Crystal Structure of Rat Metallothionein-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn68 b:22.6 occ:1.00 SG A:CYS7 2.3 22.5 1.0 SG A:CYS13 2.4 23.3 1.0 SG A:CYS15 2.4 21.8 1.0 SG A:CYS26 2.4 23.0 1.0 CB A:CYS7 3.2 21.9 1.0 CB A:CYS15 3.3 21.2 1.0 CB A:CYS13 3.3 22.8 1.0 CB A:CYS26 3.4 20.8 1.0 CD A:CD66 3.8 21.9 1.0 ZN A:ZN67 3.9 18.6 1.0 SG A:CYS24 3.9 20.9 1.0 N A:CYS15 4.1 21.4 1.0 CA A:CYS15 4.3 21.9 1.0 CA A:CYS7 4.5 21.8 1.0 CA A:CYS13 4.6 23.5 1.0 CA A:CYS26 4.7 20.4 1.0 C A:CYS13 4.7 23.4 1.0 N A:CYS26 4.9 19.4 1.0 OG A:SER28 4.9 21.6 1.0 O A:CYS13 5.0 23.5 1.0

W.Braun, M.Vasak, A.H.Robbins, C.D.Stout, G.Wagner, J.H.Kagi, K.Wuthrich. Comparison of the uc(Nmr) Solution Structure and the X-Ray Crystal Structure of Rat Metallothionein-2. Proc.Natl.Acad.Sci.Usa V. 89 10124 1992.
ISSN: ISSN 0027-8424
PubMed: 1438200
DOI: 10.1073/PNAS.89.21.10124