Zinc in PDB 4l6o: Crystal Structure of the Candida Albicans Methionine Synthase in Complex with Glutamine

All present enzymatic activity of Crystal Structure of the Candida Albicans Methionine Synthase in Complex with Glutamine:
2.1.1.14;

The structure of Crystal Structure of the Candida Albicans Methionine Synthase in Complex with Glutamine, PDB code: 4l6o was solved by D.Ubhi, J.D.Robertus, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.75 / 1.88
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	77.300, 97.175, 97.894, 90.00, 90.00, 90.00
R / Rfree (%)	17.8 / 22.5

The binding sites of Zinc atom in the Crystal Structure of the Candida Albicans Methionine Synthase in Complex with Glutamine (pdb code 4l6o). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Candida Albicans Methionine Synthase in Complex with Glutamine, PDB code: 4l6o:

Zinc binding site 1 out of 1 in the Crystal Structure of the Candida Albicans Methionine Synthase in Complex with Glutamine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Candida Albicans Methionine Synthase in Complex with Glutamine within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn801 b:53.4 occ:1.00 O A:HOH1279 1.9 38.5 1.0 SG A:CYS739 2.3 52.8 1.0 NE2 A:HIS657 2.3 49.9 1.0 SG A:CYS659 2.5 50.7 1.0 CB A:CYS739 3.0 53.5 1.0 CE1 A:HIS657 3.3 48.1 1.0 CD2 A:HIS657 3.3 45.9 1.0 CB A:CYS659 3.3 55.1 1.0 O A:ASP738 3.7 52.9 1.0 CA A:CYS659 3.7 57.8 1.0 CA A:CYS739 3.8 54.2 1.0 CD A:GLN802 3.9 45.4 1.0 OE1 A:GLN802 4.0 45.3 1.0 OE2 A:GLU679 4.1 77.0 1.0 NE2 A:GLN802 4.2 50.6 1.0 N A:CYS659 4.3 55.9 1.0 ND1 A:HIS657 4.4 43.8 1.0 CG A:GLN802 4.4 48.7 1.0 CG A:HIS657 4.4 45.5 1.0 C A:ASP738 4.5 52.7 1.0 O A:PHE658 4.6 50.5 1.0 N A:CYS739 4.6 52.0 1.0 C A:PHE658 4.6 52.8 1.0 CG A:GLU679 4.7 73.0 1.0 O A:HOH1021 4.8 33.2 1.0 CD A:GLU679 4.9 75.7 1.0 C A:CYS739 5.0 49.1 1.0 N A:GLY740 5.0 51.6 1.0

D.Ubhi, G.Kago, A.F.Monzingo, J.D.Robertus. Structural Analysis of A Fungal Methionine Synthase with Substrates and Inhibitors. J.Mol.Biol. V. 426 1839 2014.
ISSN: ISSN 0022-2836
PubMed: 24524835
DOI: 10.1016/J.JMB.2014.02.006